Karyopharm Therapeutics (KPTI) Share-based Compensation (2012 - 2025)
Karyopharm Therapeutics (KPTI) reported Share-based Compensation of $3.9 million for Q4 2025, up 1.01% on a YoY basis from $3.9 million in Q4 2024, and up 39.24% quarter-over-quarter from $2.8 million in Q3 2025.
Karyopharm Therapeutics (KPTI) Share-based Compensation (2012 - 2025) Analysis & Trends
Karyopharm Therapeutics has reported Share-based Compensation for 14 years, with the latest figure at $3.9 million in Q4 2025.
- For the quarter ending Q4 2025, Share-based Compensation rose 1.01% year-over-year to $3.9 million; the trailing twelve-month figure through Dec 2025 stood at $14.0 million (down 25.53% YoY), and the FY2025 full-year result was $14.0 million, down 23.75% from the prior year.
- Share-based Compensation for Q4 2025 stood at $3.9 million, up from $2.8 million in the prior quarter.
- The five-year high for Share-based Compensation was $15.1 million in Q2 2022, with the low at $2.8 million in Q3 2025.
- Historically, Share-based Compensation has averaged $6.0 million across 5 years, with a median of $5.4 million in 2024.
- Annual changes were most pronounced in 2022 — Share-based Compensation surged 85.53% — and 2023, when it tumbled 59.85%.
- Karyopharm Therapeutics' Share-based Compensation stood at $6.9 million in 2021, then fell by 10.13% to $6.2 million in 2022, then fell by 16.05% to $5.2 million in 2023, then retreated by 25.43% to $3.9 million in 2024, then advanced by 1.01% to $3.9 million in 2025.
- The last three Share-based Compensation figures came in at $3.9 million (Q4 2025), $2.8 million (Q3 2025), and $3.6 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Stock Comp. (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 762,369.55 Bn | 762,369.51 Bn | - | - |
| 2 | Belite Bio | 55,096.00 Bn | 55,096.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,755.80 Bn | 17,755.79 Bn | - | - |
| 4 | Legend Biotech | 3,486.00 Bn | 3,485.71 Bn | 242.10 Mn | - |
| 5 | Akari Therapeutics | 1,737.42 Bn | 1,737.41 Bn | - | 305,000.00 |
| 6 | Evaxion A | 1,551.28 Bn | 1,551.26 Bn | - | - |
| 7 | Psyence Biomedical | 227.32 Bn | 227.31 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 110.84 Bn | 103.59 Bn | 2.59 Bn | 166.40 Mn |
| 9 | Abivax | 91.71 Bn | 91.71 Bn | - | 26.47 Mn |
| 10 | Karyopharm Therapeutics | 95.31 Mn | 31.56 Mn | 32.74 Mn | 3.90 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 3.90 Mn |
| Dec 31, 2025 | 3.90 Mn |
| Sep 30, 2025 | 2.80 Mn |
| Sep 30, 2025 | 2.80 Mn |
| Jun 30, 2025 | 3.56 Mn |
| Jun 30, 2025 | 3.56 Mn |
| Mar 31, 2025 | 3.78 Mn |
| Mar 31, 2025 | 3.78 Mn |
| Dec 31, 2024 | 3.86 Mn |
| Dec 31, 2024 | 3.86 Mn |
| Sep 30, 2024 | 4.18 Mn |
| Sep 30, 2024 | 4.18 Mn |
| Jun 30, 2024 | 5.41 Mn |
| Jun 30, 2024 | 5.41 Mn |
| Mar 31, 2024 | 5.41 Mn |
| Mar 31, 2024 | 5.41 Mn |
| Dec 31, 2023 | 5.18 Mn |
| Dec 31, 2023 | 5.18 Mn |
| Sep 30, 2023 | 5.08 Mn |
| Sep 30, 2023 | 5.08 Mn |