Karyopharm Therapeutics (KPTI) Share-based Compensation (2012 - 2025)
Karyopharm Therapeutics (KPTI) recorded Share-based Compensation of $3.9 million in Q4 2025, up 1.0% from $3.86 million a year earlier and up 39.2% from the prior quarter.
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Analysis
Karyopharm Therapeutics (KPTI) Share-based Compensation (2012 - 2025) Analysis & Trends
For FY2025, Karyopharm Therapeutics reported Share-based Compensation of $14.05 million, down 23.7% from FY2024.
- Annual Share-based Compensation has declined for three straight years, with a five-year compound annual growth rate of -10.5% (FY2020 to FY2025).
- Across earlier years, Share-based Compensation came in at $18.43 million in FY2024 (-15.1%), $21.71 million in FY2023 (-38.7%), $35.4 million in FY2022 (+18.9%) and $29.78 million in FY2021 (+22.0%).
- The Q4 2025 figure is the highest quarterly Share-based Compensation since Q3 2024.
- On a year-over-year basis, Share-based Compensation rose in 1 of the last eight quarters, with an average decline of 19.0%.
- Peak year-over-year performance for Share-based Compensation in the last five years was growth of 85.5% in Q2 2022, against a decline of 59.8% in Q2 2023 at the low end.
- Per Business Quant, the preceding three quarters came in at $2.8 million (Q3 2025), $3.78 million (Q2 2025) and $3.56 million (Q1 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Stock Comp. (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 458.00 Mn |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 166.00 Mn |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | 298.00 Mn |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | - |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | - |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 165.00 Mn |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | 231.00 Mn |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 249.00 Mn |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 170.20 Mn |
| 10 | Karyopharm Therapeutics | 46.88 Mn | -179.54 Mn | 32.35 Mn | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Dec 31, 2025 | 3.90 Mn |
| Sep 30, 2025 | 2.80 Mn |
| Jun 30, 2025 | 3.78 Mn |
| Mar 31, 2025 | 3.56 Mn |
| Dec 31, 2024 | 3.86 Mn |
| Sep 30, 2024 | 4.18 Mn |
| Jun 30, 2024 | 5.41 Mn |
| Mar 31, 2024 | 4.97 Mn |
| Dec 31, 2023 | 5.18 Mn |
| Sep 30, 2023 | 5.08 Mn |
| Jun 30, 2023 | 6.06 Mn |
| Mar 31, 2023 | 5.39 Mn |
| Dec 31, 2022 | 6.17 Mn |
| Sep 30, 2022 | 6.80 Mn |
| Jun 30, 2022 | 15.09 Mn |
| Mar 31, 2022 | 7.34 Mn |
| Dec 31, 2021 | 6.87 Mn |
| Sep 30, 2021 | 7.42 Mn |
| Jun 30, 2021 | 8.14 Mn |
| Mar 31, 2021 | 7.36 Mn |
API Access
Karyopharm Therapeutics Share-based Compensation API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=share-based-compensation&ticker=KPTI&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "share-based-compensation", "ticker": "KPTI", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=share-based-compensation&ticker=KPTI&period=max&api_key=YOUR_API_KEY");
const data = await res.json();