Growth Metrics

Karyopharm Therapeutics (KPTI) Change in Cash (2016 - 2025)

Karyopharm Therapeutics (KPTI) has disclosed Change in Cash for 14 consecutive years, with $22.9 million as the latest value for Q4 2025.

  • For the quarter ending Q4 2025, Change in Cash rose 320.89% year-over-year to $22.9 million, compared with a TTM value of -$1.9 million through Dec 2025, down 119.99%, and an annual FY2025 reading of -$1.9 million, down 119.99% over the prior year.
  • Change in Cash was $22.9 million for Q4 2025 at Karyopharm Therapeutics, up from -$1.1 million in the prior quarter.
  • Across five years, Change in Cash topped out at $63.8 million in Q4 2022 and bottomed at -$70.9 million in Q2 2022.
  • Average Change in Cash over 5 years is -$1.4 million, with a median of -$3.0 million recorded in 2021.
  • The sharpest move saw Change in Cash crashed 4917.55% in 2022, then surged 1554.22% in 2024.
  • Year by year, Change in Cash stood at $57.0 million in 2021, then increased by 11.97% to $63.8 million in 2022, then tumbled by 86.51% to $8.6 million in 2023, then crashed by 220.23% to -$10.4 million in 2024, then surged by 320.89% to $22.9 million in 2025.
  • Business Quant data shows Change in Cash for KPTI at $22.9 million in Q4 2025, -$1.1 million in Q3 2025, and -$48000.0 in Q2 2025.