Karyopharm Therapeutics (KPTI) Change in Acquisitions & Divestments (2015 - 2025)
Karyopharm Therapeutics (KPTI) reported Change in Acquisitions & Divestments of $5.0 million for Q4 2025, down 69.23% on a YoY basis from $16.2 million in Q4 2024, and up 4.06% quarter-over-quarter from $4.8 million in Q3 2025.
Karyopharm Therapeutics (KPTI) Change in Acquisitions & Divestments (2015 - 2025) Analysis & Trends
Karyopharm Therapeutics has reported Change in Acquisitions & Divestments for 11 years, with the latest figure at $5.0 million in Q4 2025.
- For the quarter ending Q4 2025, Change in Acquisitions & Divestments fell 69.23% year-over-year to $5.0 million; the trailing twelve-month figure through Dec 2025 stood at $43.4 million (down 71.91% YoY), and the FY2025 full-year result was $43.4 million, down 71.91% from the prior year.
- Change in Acquisitions & Divestments for Q4 2025 stood at $5.0 million, up from $4.8 million in the prior quarter.
- The five-year high for Change in Acquisitions & Divestments was $69.0 million in Q1 2021, with the low at $4.8 million in Q3 2025.
- Historically, Change in Acquisitions & Divestments has averaged $34.0 million across 5 years, with a median of $31.1 million in 2021.
- Annual changes were most pronounced in 2023 — Change in Acquisitions & Divestments soared 113.38% — and 2025, when it plunged 83.01%.
- Karyopharm Therapeutics' Change in Acquisitions & Divestments stood at $30.5 million in 2021, then increased by 4.34% to $31.8 million in 2022, then surged by 36.49% to $43.4 million in 2023, then tumbled by 62.56% to $16.2 million in 2024, then tumbled by 69.23% to $5.0 million in 2025.
- The last three Change in Acquisitions & Divestments figures came in at $5.0 million (Q4 2025), $4.8 million (Q3 2025), and $18.3 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Alterity Therapeutics | 762,369.55 Bn | 762,369.51 Bn | - |
| 2 | Belite Bio | 55,096.00 Bn | 55,096.00 Bn | - |
| 3 | Quantum Biopharma | 17,755.80 Bn | 17,755.79 Bn | - |
| 4 | Legend Biotech | 3,486.00 Bn | 3,485.71 Bn | 242.10 Mn |
| 5 | Akari Therapeutics | 1,737.42 Bn | 1,737.41 Bn | - |
| 6 | Evaxion A | 1,551.28 Bn | 1,551.26 Bn | - |
| 7 | Psyence Biomedical | 227.32 Bn | 227.31 Bn | - |
| 8 | Vertex Pharmaceuticals | 110.84 Bn | 103.59 Bn | 2.59 Bn |
| 9 | Abivax | 91.71 Bn | 91.71 Bn | - |
| 10 | Karyopharm Therapeutics | 95.31 Mn | 31.56 Mn | 32.74 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 5.00 Mn |
| Dec 31, 2025 | 5.00 Mn |
| Sep 30, 2025 | 4.81 Mn |
| Sep 30, 2025 | 4.81 Mn |
| Jun 30, 2025 | 18.29 Mn |
| Jun 30, 2025 | 18.29 Mn |
| Mar 31, 2025 | 15.29 Mn |
| Mar 31, 2025 | 15.29 Mn |
| Dec 31, 2024 | 16.25 Mn |
| Dec 31, 2024 | 16.25 Mn |
| Sep 30, 2024 | 28.28 Mn |
| Sep 30, 2024 | 28.28 Mn |
| Jun 30, 2024 | 56.17 Mn |
| Jun 30, 2024 | 56.17 Mn |
| Mar 31, 2024 | 53.74 Mn |
| Mar 31, 2024 | 53.74 Mn |
| Dec 31, 2023 | 43.40 Mn |
| Dec 31, 2023 | 43.40 Mn |
| Sep 30, 2023 | 38.38 Mn |
| Sep 30, 2023 | 38.38 Mn |