Karyopharm Therapeutics (KPTI) Cash & Equivalents (2012 - 2026)
Karyopharm Therapeutics' (KPTI) quarterly Cash & Equivalents came in at $47.7 million in Q4 2025, down 51.44% YoY from $98.3 million in Q4 2024, and up 35.07% on a QoQ basis from $35.3 million in Q3 2025.
Karyopharm Therapeutics (KPTI) Cash & Equivalents (2012 - 2026) Analysis & Trends
Karyopharm Therapeutics (KPTI) has 14 years of Cash & Equivalents data on file, last reported at $47.7 million in Q4 2025.
- Quarterly Cash & Equivalents fell 51.44% year-over-year to $47.7 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was $47.7 million (down 51.44% YoY) and the FY2025 annual result came in at $47.7 million, down 51.44% from the prior year.
- Cash & Equivalents advanced to $47.7 million in Q4 2025, from $35.3 million in the prior quarter.
- In the past five years, Cash & Equivalents ranged from a high of $153.3 million in Q1 2022 to a low of $545000.0 in Q3 2023.
- A 5-year average of $55.0 million and a median of $50.0 million in 2023 frame the typical range for Cash & Equivalents.
- Annual changes were most pronounced in 2021 — Cash & Equivalents slumped 99.6% — and 2022, when it jumped 18704.42%.
- Tracing KPTI's Cash & Equivalents over 5 years: stood at $6.3 million in 2021, then surged by 2029.28% to $135.2 million in 2022, then slumped by 61.36% to $52.2 million in 2023, then surged by 88.2% to $98.3 million in 2024, then slumped by 51.44% to $47.7 million in 2025.
- The last three Cash & Equivalents figures came in at $47.7 million (Q4 2025), $35.3 million (Q3 2025), and $34.9 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Cash & Equiv. (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 139.13 Bn | 131.28 Bn | 2.84 Bn | 6.14 Bn |
| 2 | Regeneron Pharmaceuticals | 85.77 Bn | 77.77 Bn | 3.93 Bn | 2.46 Bn |
| 3 | Argenx Se | 64.64 Bn | 59.46 Bn | 1.37 Bn | 3.58 Bn |
| 4 | Moderna | 58.29 Bn | 53.16 Bn | 52.00 Mn | 1.72 Bn |
| 5 | BeOne Medicines | 41.92 Bn | 36.82 Bn | 1.53 Bn | 5.10 Bn |
| 6 | Alnylam Pharmaceuticals | 31.58 Bn | 28.28 Bn | 992.69 Mn | 1.71 Bn |
| 7 | BioNTech SE | 28.12 Bn | 9.73 Bn | 668.28 Mn | 8.93 Bn |
| 8 | Insmed | 27.39 Bn | 26.22 Bn | 358.27 Mn | 544.80 Mn |
| 9 | Royalty Pharma | 27.27 Bn | 26.43 Bn | - | 811.99 Mn |
| 10 | Karyopharm Therapeutics | 56.72 Mn | 56.72 Mn | 32.35 Mn | 54.98 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | 54.98 Mn |
| Dec 31, 2025 | 47.73 Mn |
| Sep 30, 2025 | 35.34 Mn |
| Jun 30, 2025 | 34.90 Mn |
| Mar 31, 2025 | 54.28 Mn |
| Dec 31, 2024 | 98.30 Mn |
| Sep 30, 2024 | 72.83 Mn |
| Jun 30, 2024 | 84.77 Mn |
| Mar 31, 2024 | 30.63 Mn |
| Dec 31, 2023 | 52.23 Mn |
| Sep 30, 2023 | 545,000.00 |
| Jun 30, 2023 | 80.89 Mn |
| Mar 31, 2023 | 846,000.00 |
| Dec 31, 2022 | 135.19 Mn |
| Sep 30, 2022 | 71.35 Mn |
| Jun 30, 2022 | 1.15 Mn |
| Mar 31, 2022 | 153.26 Mn |
| Dec 31, 2021 | 6.35 Mn |
| Sep 30, 2021 | 137.40 Mn |
| Jun 30, 2021 | 762,000.00 |