Karyopharm Therapeutics KPTI
NASDAQ KPTI
$1.96 +0.14 (+7.69%)
At close: Aug 21, 2026 · 4:00 PM EDT

Karyopharm Therapeutics (KPTI) Cash & Equivalents (2012 - 2026)

Karyopharm Therapeutics' (KPTI) quarterly Cash & Equivalents came in at $47.7 million in Q4 2025, down 51.44% YoY from $98.3 million in Q4 2024, and up 35.07% on a QoQ basis from $35.3 million in Q3 2025.

Karyopharm Therapeutics (KPTI) Cash & Equivalents (2012 - 2026) Analysis & Trends

Karyopharm Therapeutics (KPTI) has 14 years of Cash & Equivalents data on file, last reported at $47.7 million in Q4 2025.

  • Quarterly Cash & Equivalents fell 51.44% year-over-year to $47.7 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was $47.7 million (down 51.44% YoY) and the FY2025 annual result came in at $47.7 million, down 51.44% from the prior year.
  • Cash & Equivalents advanced to $47.7 million in Q4 2025, from $35.3 million in the prior quarter.
  • In the past five years, Cash & Equivalents ranged from a high of $153.3 million in Q1 2022 to a low of $545000.0 in Q3 2023.
  • A 5-year average of $55.0 million and a median of $50.0 million in 2023 frame the typical range for Cash & Equivalents.
  • Annual changes were most pronounced in 2021 — Cash & Equivalents slumped 99.6% — and 2022, when it jumped 18704.42%.
  • Tracing KPTI's Cash & Equivalents over 5 years: stood at $6.3 million in 2021, then surged by 2029.28% to $135.2 million in 2022, then slumped by 61.36% to $52.2 million in 2023, then surged by 88.2% to $98.3 million in 2024, then slumped by 51.44% to $47.7 million in 2025.
  • The last three Cash & Equivalents figures came in at $47.7 million (Q4 2025), $35.3 million (Q3 2025), and $34.9 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cash & Equiv. (Qtr)
1 Vertex Pharmaceuticals 139.13 Bn 131.28 Bn 2.84 Bn 6.14 Bn
2 Regeneron Pharmaceuticals 85.77 Bn 77.77 Bn 3.93 Bn 2.46 Bn
3 Argenx Se 64.64 Bn 59.46 Bn 1.37 Bn 3.58 Bn
4 Moderna 58.29 Bn 53.16 Bn 52.00 Mn 1.72 Bn
5 BeOne Medicines 41.92 Bn 36.82 Bn 1.53 Bn 5.10 Bn
6 Alnylam Pharmaceuticals 31.58 Bn 28.28 Bn 992.69 Mn 1.71 Bn
7 BioNTech SE 28.12 Bn 9.73 Bn 668.28 Mn 8.93 Bn
8 Insmed 27.39 Bn 26.22 Bn 358.27 Mn 544.80 Mn
9 Royalty Pharma 27.27 Bn 26.43 Bn - 811.99 Mn
10 Karyopharm Therapeutics 56.72 Mn 56.72 Mn 32.35 Mn 54.98 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 54.98 Mn
Dec 31, 2025 47.73 Mn
Sep 30, 2025 35.34 Mn
Jun 30, 2025 34.90 Mn
Mar 31, 2025 54.28 Mn
Dec 31, 2024 98.30 Mn
Sep 30, 2024 72.83 Mn
Jun 30, 2024 84.77 Mn
Mar 31, 2024 30.63 Mn
Dec 31, 2023 52.23 Mn
Sep 30, 2023 545,000.00
Jun 30, 2023 80.89 Mn
Mar 31, 2023 846,000.00
Dec 31, 2022 135.19 Mn
Sep 30, 2022 71.35 Mn
Jun 30, 2022 1.15 Mn
Mar 31, 2022 153.26 Mn
Dec 31, 2021 6.35 Mn
Sep 30, 2021 137.40 Mn
Jun 30, 2021 762,000.00