Karyopharm Therapeutics (KPTI) Cash & Equivalents (2012 - 2025)

Karyopharm Therapeutics (KPTI) reported Cash & Equivalents of $60.5 million for Q4 2025, down 38.41% on a YoY basis from $98.3 million in Q4 2024, and up 60.7% quarter-over-quarter from $37.7 million in Q3 2025.

Karyopharm Therapeutics (KPTI) Cash & Equivalents (2012 - 2025) Analysis & Trends

Karyopharm Therapeutics has reported Cash & Equivalents for 14 years, with the latest figure at $60.5 million in Q4 2025.

  • For the quarter ending Q4 2025, Cash & Equivalents fell 38.41% year-over-year to $60.5 million; the trailing twelve-month figure through Dec 2025 stood at $60.5 million (down 38.41% YoY), and the FY2025 full-year result was $60.5 million, down 38.41% from the prior year.
  • Cash & Equivalents for Q4 2025 stood at $60.5 million, up from $37.7 million in the prior quarter.
  • The five-year high for Cash & Equivalents was $98.3 million in Q4 2024, with the low at $545000.0 in Q3 2023.
  • Historically, Cash & Equivalents has averaged $39.6 million across 5 years, with a median of $36.3 million in 2025.
  • Annual changes were most pronounced in 2021 — Cash & Equivalents slumped 99.26% — and 2024, when it soared 13262.94%.
  • Karyopharm Therapeutics' Cash & Equivalents stood at $6.3 million in 2021, then tumbled by 83.24% to $1.1 million in 2022, then jumped by 4808.93% to $52.2 million in 2023, then surged by 88.2% to $98.3 million in 2024, then tumbled by 38.41% to $60.5 million in 2025.
  • The last three Cash & Equivalents figures came in at $60.5 million (Q4 2025), $37.7 million (Q3 2025), and $34.9 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cash & Equiv. (Qtr)
1 Alterity Therapeutics 762,369.55 Bn 762,369.51 Bn - 32.30 Mn
2 Belite Bio 55,096.00 Bn 55,096.00 Bn - -
3 Quantum Biopharma 17,755.80 Bn 17,755.79 Bn - 1.91 Mn
4 Legend Biotech 3,486.00 Bn 3,485.71 Bn 242.10 Mn 286.70 Mn
5 Akari Therapeutics 1,737.42 Bn 1,737.41 Bn - 2.77 Mn
6 Evaxion A 1,551.28 Bn 1,551.26 Bn - 18.44 Mn
7 Psyence Biomedical 227.32 Bn 227.31 Bn - 7.15 Mn
8 Vertex Pharmaceuticals 110.84 Bn 103.59 Bn 2.59 Bn 5.49 Bn
9 Abivax 91.71 Bn 91.71 Bn - 558.94 Mn
10 Karyopharm Therapeutics 95.31 Mn 31.56 Mn 32.74 Mn 60.54 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 60.54 Mn
Sep 30, 2025 37.67 Mn
Jun 30, 2025 34.90 Mn
Mar 31, 2025 54.28 Mn
Dec 31, 2024 98.30 Mn
Sep 30, 2024 72.83 Mn
Jun 30, 2024 84.77 Mn
Mar 31, 2024 30.63 Mn
Dec 31, 2023 52.23 Mn
Sep 30, 2023 545,000.00
Jun 30, 2023 80.89 Mn
Mar 31, 2023 846,000.00
Dec 31, 2022 1.06 Mn
Sep 30, 2022 1.08 Mn
Jun 30, 2022 82.25 Mn
Mar 31, 2022 1.01 Mn
Dec 31, 2021 6.35 Mn
Sep 30, 2021 2.40 Mn
Jun 30, 2021 762,000.00
Mar 31, 2021 88.47 Mn