Balance Sheet
Cash Flow Statement
Amortization of Deferred ChargesAmortizatization of IntangiblesCapital ExpendituresCash from Financing ActivitiesCash from Investing ActivitiesCash from OperationsChange in Account PayablesChange in Accured ExpensesChange in Acquisitions & DivestmentsChange in CashChange in InventoryChange in ReceivablesDepreciation & Amortization (CF)Depreciation and DepletionExchange Rate EffectFree Cash FlowGains from Investment SecuritiesGains from Sales and DivestituresLong-Term Debt RepaymentsNet Cash FlowNet IncomeNon-cash ItemsOther Working Capital ChangesShare-based CompensationShares Issued
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Karyopharm Therapeutics (KPTI) Net Cash Flow (2016 - 2025)

Karyopharm Therapeutics' Net Cash Flow history spans 14 years, with the latest figure at $22.9 million for Q4 2025.

  • For Q4 2025, Net Cash Flow rose 321.27% year-over-year to $22.9 million; the TTM value through Dec 2025 reached -$2.3 million, up 92.66%, while the annual FY2025 figure was -$1.9 million, 120.17% down from the prior year.
  • Net Cash Flow reached $22.9 million in Q4 2025 per KPTI's latest filing, up from -$1.1 million in the prior quarter.
  • In the past five years, Net Cash Flow ranged from a high of $63.7 million in Q4 2022 to a low of -$70.4 million in Q2 2022.
  • Average Net Cash Flow over 5 years is -$3.4 million, with a median of -$3.1 million recorded in 2021.
  • Peak YoY movement for Net Cash Flow: skyrocketed 1107.8% in 2021, then tumbled 4458.21% in 2022.
  • A 5-year view of Net Cash Flow shows it stood at $57.1 million in 2021, then increased by 11.48% to $63.7 million in 2022, then plummeted by 86.62% to $8.5 million in 2023, then crashed by 221.25% to -$10.3 million in 2024, then skyrocketed by 321.27% to $22.9 million in 2025.
  • Per Business Quant, the three most recent readings for KPTI's Net Cash Flow are $22.9 million (Q4 2025), -$1.1 million (Q3 2025), and -$412000.0 (Q2 2025).