Karyopharm Therapeutics (KPTI) Cash & Current Investments (2012 - 2025)

Karyopharm Therapeutics (KPTI) reported Cash & Current Investments of $63.7 million for Q4 2025, down 55.9% on a YoY basis from $144.5 million in Q4 2024, and up 38.95% quarter-over-quarter from $45.9 million in Q3 2025.

Karyopharm Therapeutics (KPTI) Cash & Current Investments (2012 - 2025) Analysis & Trends

Karyopharm Therapeutics has reported Cash & Current Investments for 14 years, with the latest figure at $63.7 million in Q4 2025.

  • For the quarter ending Q4 2025, Cash & Current Investments fell 55.9% year-over-year to $63.7 million; the trailing twelve-month figure through Dec 2025 stood at $63.7 million (down 55.9% YoY), and the FY2025 full-year result was $63.7 million, down 55.9% from the prior year.
  • Cash & Current Investments for Q4 2025 stood at $63.7 million, up from $45.9 million in the prior quarter.
  • The five-year high for Cash & Current Investments was $236.8 million in Q2 2023, with the low at $44.5 million in Q4 2021.
  • Historically, Cash & Current Investments has averaged $123.6 million across 5 years, with a median of $138.7 million in 2022.
  • Annual changes were most pronounced in 2022 — Cash & Current Investments sank 76.35% — and 2023, when it soared 233.84%.
  • Karyopharm Therapeutics' Cash & Current Investments stood at $44.5 million in 2021, then jumped by 223.21% to $143.8 million in 2022, then jumped by 33.09% to $191.4 million in 2023, then fell by 24.5% to $144.5 million in 2024, then plunged by 55.9% to $63.7 million in 2025.
  • The last three Cash & Current Investments figures came in at $63.7 million (Q4 2025), $45.9 million (Q3 2025), and $47.9 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cash & Current Investments (Qtr)
1 Alterity Therapeutics 762,369.55 Bn 762,369.51 Bn - 32.30 Mn
2 Belite Bio 55,096.00 Bn 55,096.00 Bn - -
3 Quantum Biopharma 17,755.80 Bn 17,755.79 Bn - 2.13 Mn
4 Legend Biotech 3,486.00 Bn 3,485.71 Bn 242.10 Mn 286.70 Mn
5 Akari Therapeutics 1,737.42 Bn 1,737.41 Bn - 2.77 Mn
6 Evaxion A 1,551.28 Bn 1,551.26 Bn - 18.44 Mn
7 Psyence Biomedical 227.32 Bn 227.31 Bn - 7.20 Mn
8 Vertex Pharmaceuticals 110.84 Bn 103.59 Bn 2.59 Bn 7.25 Bn
9 Abivax 91.71 Bn 91.71 Bn - -
10 Karyopharm Therapeutics 95.31 Mn 31.56 Mn 32.74 Mn 63.74 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 63.74 Mn
Sep 30, 2025 45.88 Mn
Jun 30, 2025 47.88 Mn
Mar 31, 2025 85.43 Mn
Dec 31, 2024 144.53 Mn
Sep 30, 2024 133.53 Mn
Jun 30, 2024 152.12 Mn
Mar 31, 2024 148.58 Mn
Dec 31, 2023 191.44 Mn
Sep 30, 2023 165.21 Mn
Jun 30, 2023 236.77 Mn
Mar 31, 2023 177.17 Mn
Dec 31, 2022 143.84 Mn
Sep 30, 2022 78.11 Mn
Jun 30, 2022 170.85 Mn
Mar 31, 2022 53.07 Mn
Dec 31, 2021 44.51 Mn
Sep 30, 2021 69.21 Mn
Jun 30, 2021 95.34 Mn
Mar 31, 2021 224.37 Mn