Karyopharm Therapeutics (KPTI) Cash from Investing Activities (2013 - 2025)
Karyopharm Therapeutics' Cash from Investing Activities was $5 million in Q4 2025, down 66.2% from $14.8 million a year earlier but up 4.1% from the prior quarter.
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Analysis
Karyopharm Therapeutics (KPTI) Cash from Investing Activities (2013 - 2025) Analysis & Trends
For FY2025, Cash from Investing Activities at Karyopharm Therapeutics came in at $43.38 million, down 54.6% from FY2024.
- In earlier years, Cash from Investing Activities was $95.47 million in FY2024, $7.94 million in FY2023, -$104.26 million in FY2022 and $141.84 million in FY2021.
- Quarterly Cash from Investing Activities has moved between -$65.3 million (Q4 2022) and $51.26 million (Q2 2024) over five years.
- Compared with a year earlier, Cash from Investing Activities has declined for five straight quarters, with an average decline of 16.6% over the last six quarters.
- The best year-over-year quarter for Cash from Investing Activities over five years was Q2 2024 (growth of 142.1%); the worst was Q4 2025 (a decline of 66.2%).
- Per Business Quant data, KPTI's Cash from Investing Activities in the three quarters before Q4 2025 was $4.81 million (Q3 2025), $18.29 million (Q2 2025) and $15.29 million (Q1 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Cash from Investing (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,076.25 Bn | 1,044.84 Bn | 19.71 Bn | -15.40 Bn |
| 2 | Johnson & Johnson | 617.18 Bn | 535.70 Bn | 17.26 Bn | -1.11 Bn |
| 3 | AbbVie | 464.58 Bn | 437.73 Bn | 12.70 Bn | -1.20 Bn |
| 4 | Merck | 356.04 Bn | 310.47 Bn | 12.21 Bn | -5.60 Bn |
| 5 | Novartis Ag | 269.07 Bn | 224.94 Bn | 11.24 Bn | -3.11 Bn |
| 6 | Astrazeneca | 243.21 Bn | 216.77 Bn | 12.86 Bn | -2.91 Bn |
| 7 | Amgen | 217.88 Bn | 173.28 Bn | 7.24 Bn | -569.00 Mn |
| 8 | Gilead Sciences | 179.62 Bn | 153.74 Bn | 6.22 Bn | -10.35 Bn |
| 9 | Pfizer | 158.45 Bn | 105.40 Bn | 10.94 Bn | 2.11 Bn |
| 10 | Karyopharm Therapeutics | 23.15 Mn | -203.27 Mn | 32.35 Mn | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Dec 31, 2025 | 5.00 Mn |
| Sep 30, 2025 | 4.81 Mn |
| Jun 30, 2025 | 18.29 Mn |
| Mar 31, 2025 | 15.29 Mn |
| Dec 31, 2024 | 14.80 Mn |
| Sep 30, 2024 | 7.47 Mn |
| Jun 30, 2024 | 51.26 Mn |
| Mar 31, 2024 | 21.94 Mn |
| Dec 31, 2023 | 26.84 Mn |
| Sep 30, 2023 | -7.69 Mn |
| Jun 30, 2023 | 21.17 Mn |
| Mar 31, 2023 | -32.39 Mn |
| Dec 31, 2022 | -65.30 Mn |
| Sep 30, 2022 | 11.67 Mn |
| Jun 30, 2022 | -36.60 Mn |
| Mar 31, 2022 | -14.04 Mn |
| Dec 31, 2021 | 30.77 Mn |
| Sep 30, 2021 | 21.43 Mn |
| Jun 30, 2021 | 46.46 Mn |
| Mar 31, 2021 | 43.19 Mn |
API Access
Karyopharm Therapeutics Cash from Investing Activities API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=cash-from-investing-activities&ticker=KPTI&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "cash-from-investing-activities", "ticker": "KPTI", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=cash-from-investing-activities&ticker=KPTI&period=max&api_key=YOUR_API_KEY");
const data = await res.json();