Karyopharm Therapeutics (KPTI) Cash from Investing Activities (2013 - 2025)
Karyopharm Therapeutics (KPTI) reported Cash from Investing Activities of $5.0 million for Q4 2025, down 66.21% on a YoY basis from $14.8 million in Q4 2024, and up 4.06% quarter-over-quarter from $4.8 million in Q3 2025.
Karyopharm Therapeutics (KPTI) Cash from Investing Activities (2013 - 2025) Analysis & Trends
Karyopharm Therapeutics has reported Cash from Investing Activities for 13 years, with the latest figure at $5.0 million in Q4 2025.
- For the quarter ending Q4 2025, Cash from Investing Activities fell 66.21% year-over-year to $5.0 million; the trailing twelve-month figure through Dec 2025 stood at $43.4 million (down 54.57% YoY), and the FY2025 full-year result was $43.4 million, down 54.57% from the prior year.
- Cash from Investing Activities for Q4 2025 stood at $5.0 million, up from $4.8 million in the prior quarter.
- The five-year high for Cash from Investing Activities was $51.3 million in Q2 2024, with the low at -$65.3 million in Q4 2022.
- Historically, Cash from Investing Activities has averaged $9.2 million across 5 years, with a median of $15.0 million in 2024.
- Annual changes were most pronounced in 2022 — Cash from Investing Activities tumbled 312.21% — and 2024, when it jumped 197.25%.
- Karyopharm Therapeutics' Cash from Investing Activities stood at $30.8 million in 2021, then tumbled by 312.21% to -$65.3 million in 2022, then soared by 141.11% to $26.8 million in 2023, then tumbled by 44.88% to $14.8 million in 2024, then tumbled by 66.21% to $5.0 million in 2025.
- The last three Cash from Investing Activities figures came in at $5.0 million (Q4 2025), $4.8 million (Q3 2025), and $18.3 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Cash from Investing (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 762,369.55 Bn | 762,369.51 Bn | - | - |
| 2 | Belite Bio | 55,096.00 Bn | 55,096.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,755.80 Bn | 17,755.79 Bn | - | -2.89 Mn |
| 4 | Legend Biotech | 3,486.00 Bn | 3,485.71 Bn | 242.10 Mn | 638.50 Mn |
| 5 | Akari Therapeutics | 1,737.42 Bn | 1,737.41 Bn | - | - |
| 6 | Evaxion A | 1,551.28 Bn | 1,551.26 Bn | - | - |
| 7 | Psyence Biomedical | 227.32 Bn | 227.31 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 110.84 Bn | 103.59 Bn | 2.59 Bn | -431.90 Mn |
| 9 | Abivax | 91.71 Bn | 91.71 Bn | - | 579,519.10 |
| 10 | Karyopharm Therapeutics | 95.31 Mn | 31.56 Mn | 32.74 Mn | 5.00 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 5.00 Mn |
| Dec 31, 2025 | 5.00 Mn |
| Sep 30, 2025 | 4.81 Mn |
| Sep 30, 2025 | 4.81 Mn |
| Jun 30, 2025 | 18.29 Mn |
| Jun 30, 2025 | 18.29 Mn |
| Mar 31, 2025 | 15.29 Mn |
| Mar 31, 2025 | 15.29 Mn |
| Dec 31, 2024 | 14.80 Mn |
| Dec 31, 2024 | 14.80 Mn |
| Sep 30, 2024 | 7.47 Mn |
| Sep 30, 2024 | 7.47 Mn |
| Jun 30, 2024 | 51.26 Mn |
| Jun 30, 2024 | 51.26 Mn |
| Mar 31, 2024 | 21.94 Mn |
| Mar 31, 2024 | 21.94 Mn |
| Dec 31, 2023 | 26.84 Mn |
| Dec 31, 2023 | 26.84 Mn |
| Sep 30, 2023 | -7.69 Mn |
| Sep 30, 2023 | -7.69 Mn |