Prime Medicine (PRME) EBIT Margin (2024 - 2026)

Prime Medicine (PRME) posted EBIT Margin of 5917.52% for Q1 2026, down 2.02% on a QoQ basis from 5800.48% in Q4 2025, and down 231422.0% year-over-year from N/an in Q1 2025.

Prime Medicine (PRME) EBIT Margin (2024 - 2026) Analysis & Trends

Prime Medicine's EBIT Margin history runs 3 years deep, the most recent figure standing at 5917.52% for Q1 2026.

  • Quarterly EBIT Margin fell 231422.0% year-over-year to 5917.52% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 5121.76% (up 24792.0% YoY) and the FY2025 annual result came in at 4498.06%, up 228930.0% from the prior year.
  • EBIT Margin was 5917.52% for Q1 2026 at Prime Medicine, down from 5800.48% in the prior quarter.
  • Across five years, EBIT Margin topped out at 2025.74% in Q4 2024 and bottomed at 25948.33% in Q3 2024.
  • A 3-year average of 7583.5% and a median of 5293.83% in 2025 frame the typical range for EBIT Margin.
  • Peak annual rise in EBIT Margin reached 2154237 bps in 2025, while the deepest fall reached 377473 bps in 2025.
  • Prime Medicine's EBIT Margin stood at 2025.74% in 2024, then plunged by 186 bps to 5800.48% in 2025, then dropped by 2 bps to 5917.52% in 2026.
  • Business Quant data shows PRME's EBIT Margin at 5917.52% in Q1 2026, 5800.48% in Q4 2025, and 4405.96% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIT Margin (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 16.51%
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 38.10%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 17.83%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 31.68%
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Prime Medicine 525.98 Mn 525.98 Mn - -5,917.52%

Historic Data

Download Data
DateValue
Mar 31, 2026 -5,917.52%
Dec 31, 2025 -5,800.48%
Sep 30, 2025 -4,405.96%
Jun 30, 2025 -4,787.17%
Mar 31, 2025 -3,603.30%
Dec 31, 2024 -2,025.74%
Sep 30, 2024 -25,948.33%
Mar 31, 2024 -8,179.53%