Prime Medicine (PRME) EBIT Margin (2024 - 2026)
Prime Medicine posted quarterly EBIT Margin of 5917.52% for Q1 2026, down 231422.0% year-on-year from N/an in Q1 2025, and down 2.02% on a QoQ basis from 5800.48% in Q4 2025.
Prime Medicine (PRME) has 3 years of EBIT Margin data on file, last reported at 5917.52% in Q1 2026.
- For the quarter ending Q1 2026, EBIT Margin fell 231422.0% year-over-year to 5917.52%; the trailing twelve-month figure through Mar 2026 stood at 5121.76% (up 24792.0% YoY), and the FY2025 full-year result was 4498.06%, up 228930.0% from the prior year.
- EBIT Margin for Q1 2026 stood at 5917.52%, down from 5800.48% in the prior quarter.
- Across five years, EBIT Margin topped out at 2025.74% in Q4 2024 and bottomed at 25948.33% in Q3 2024.
- The 3-year median for EBIT Margin is 5293.83% (2025), against an average of 7583.5%.
- Peak annual rise in EBIT Margin reached 2154237 bps in 2025, while the deepest fall reached 377473 bps in 2025.
- A 3-year view of EBIT Margin shows it stood at 2025.74% in 2024, then sank by 186 bps to 5800.48% in 2025, then slipped by 2 bps to 5917.52% in 2026.
- The last three EBIT Margin figures came in at 5917.52% (Q1 2026), 5800.48% (Q4 2025), and 4405.96% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBIT Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | - |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | -6.43% |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | - |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 38.10% |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 17.83% |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 23.02% |
| 10 | Prime Medicine | 601.24 Mn | 601.24 Mn | - | -5,917.52% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -5,917.52% |
| Dec 31, 2025 | -5,800.48% |
| Sep 30, 2025 | -4,405.96% |
| Jun 30, 2025 | -4,787.17% |
| Mar 31, 2025 | -3,603.30% |
| Dec 31, 2024 | -2,025.74% |
| Sep 30, 2024 | -25,948.33% |
| Mar 31, 2024 | -8,179.53% |