Prime Medicine PRME Institutional Ownership

NASDAQ PRME

$3.06 -0.03 (-0.97%)

At close: Sep 30, 2026 · 4:00 PM EDT

Institutions by Trading Activity

189 Institutions

Increased 89 47.1%

Unchanged 33 17.5%

Reduced 67 35.4%

Ownership Statistics

13F · as of 30 Jun, 2026

Institutional Ownership

60.70%

▲+5.16 pp QoQ

Shares Held by Institutions

107.58Mn

of 177.22Mn outstanding

▲+10.04% QoQ

Shares Outstanding

177.22Mn

69.64Mn held outside 13F filers

Institutional Investors

189

filed 13F for Jun 2026

▼-2 vs prior quarter

Net Shares Added (QoQ)

+9.82Mn

accumulated since last quarter

Value of Holdings

$329.20Mn

reported market value

Shares Owned by Institutions

Shares held % of outstanding

Latest —

Average ownership —

Peak ownership —

Shares Purchased/Sold by Institutions

Accumulated Distributed

Latest quarter —

Net over range —

Accumulating quarters —

Ownership Summary

Quarter ending 30 Jun, 2026

Prime Medicine, Inc. (NASDAQ:PRME) has 189 institutional investors with active 13F positions as of June 2026.

They owned 60.7% of outstanding stock in June 2026, up from 55.5% the prior quarter.
Their total shares held in PRME increased 10.04% from the prior quarter, while the number of investors in Prime Medicine increased 58.82% year over year.
Of these 189 funds, 89 grew their exposure to Prime Medicine, 67 cut back, and 33 maintained positions.
Institutional investors collectively held 107.58Mn shares in Prime Medicine as of June 2026, up by 9.82Mn shares quarter on quarter, and up 50.35Mn shares year over year.
As of June 30, 2026, Alphabet Inc. held the largest stake in Prime Medicine with 16.56Mn shares, accounting for 9.35% of total shares outstanding.
The biggest buyers of Prime Medicine for the quarter ending June 2026 included Goldman Sachs Group Inc (2.46Mn), ARK Investment Management LLC (2.1Mn), CITADEL ADVISORS LLC (1.72Mn), Jump Financial, LLC (1.24Mn), State Street Corp (1.23Mn).
Top sellers of PRME stock for the quarter ending June 2026 included D. E. Shaw & Co., Inc. (744.68K), RENAISSANCE TECHNOLOGIES LLC (623.63K), Amova Asset Management Americas, Inc. (533.78K), Sumitomo Mitsui Trust Group, Inc. (527.81K), HRT FINANCIAL LP (451.26K).
Prime Medicine's 10 largest shareholders as of June 2026 include Alphabet Inc. (16.56Mn), BlackRock, Inc. (9.6Mn), ARK Investment Management LLC (8.35Mn), State Street Corp (7.58Mn), T. Rowe Price Investment Management, Inc. (5.24Mn), VANGUARD CAPITAL MANAGEMENT LLC (4.52Mn), BALYASNY ASSET MANAGEMENT L.P. (3.97Mn), Goldman Sachs Group Inc (3.43Mn), Casdin Capital, LLC (3.17Mn), Woodline Partners LP (3.0Mn) per Business Quant data.

Form 13F Holdings

189 Institutional Holders

Report period 30 Jun, 2026

Total shares held 107.58Mn

Of outstanding 60.70%

#	Institution	CIK	Shares Held	% of Outstanding	Change (QoQ)	Change (%)	Value (USD)
1	Alphabet Inc.	0001652044	16,562,498	9.35%	0	0.00%	$61.12Mn
2	BlackRock, Inc.	0002012383	9,602,041	5.42%	▲1,100,333	+12.94%	$35.43Mn
3	ARK Investment Management LLC	0001697748	8,348,746	4.71%	▲2,101,919	+33.65%	$30.81Mn
4	State Street Corp	0000093751	7,576,460	4.28%	▲1,231,335	+19.41%	$27.96Mn
5	T. Rowe Price Investment Management, Inc.	0001897612	5,237,332	2.96%	▼244,561	-4.46%	$19.33K
6	VANGUARD CAPITAL MANAGEMENT LLC	0002100119	4,522,640	2.55%	▲48,478	+1.08%	$16.69Mn
7	BALYASNY ASSET MANAGEMENT L.P.	0001218710	3,969,082	2.24%	▼154,283	-3.74%	$14.65Mn
8	Goldman Sachs Group Inc	0000886982	3,430,518	1.94%	▲2,460,093	+253.51%	$12.66Mn
9	Casdin Capital, LLC	0001534261	3,167,175	1.79%	0	0.00%	$11.69Mn
10	Woodline Partners LP	0001784547	3,003,904	1.69%	▲591	+0.02%	$11.08Mn
11	UBS Group AG	0001610520	2,794,689	1.58%	▼93,729	-3.24%	$10.31Mn
12	GEODE CAPITAL MANAGEMENT, LLC	0001214717	2,712,446	1.53%	▼31,254	-1.14%	$10.01Mn
13	Sumitomo Mitsui Trust Group, Inc.	0001475365	2,412,984	1.36%	▼527,809	-17.95%	$8.90Mn
14	Amova Asset Management Americas, Inc.	0001480751	2,407,018	1.36%	▼533,775	-18.15%	$8.86Mn
15	CITADEL ADVISORS LLC	0001423053	2,054,543	1.16%	▲1,718,185	+510.82%	$7.58Mn
16	ADAR1 Capital Management, LLC	0001940272	1,997,552	1.13%	▲24,270	+1.23%	$7.37Mn
17	FMR LLC	0000315066	1,761,884	0.99%	▼7,592	-0.43%	$6.50Mn
18	TWO SIGMA INVESTMENTS, LP	0001179392	1,524,511	0.86%	▼48,300	-3.07%	$5.63Mn
19	Redmile Group, LLC	0001425738	1,389,632	0.78%	▼201,200	-12.65%	$5.13Mn
20	FARALLON CAPITAL MANAGEMENT, L.L.C.	0000909661	1,240,843	0.70%	0	0.00%	$4.58Mn

Showing 1 to 20 of 189 holders