Prime Medicine (PRME) EPS (Basic) (2021 - 2026)

Prime Medicine (PRME) reported EPS (Basic) of -$0.28 for Q1 2026, up 30.0% on a YoY basis from -$0.22 in Q1 2025, and down 16.67% quarter-over-quarter from -$0.24 in Q4 2025.

Prime Medicine (PRME) EPS (Basic) (2021 - 2026) Analysis & Trends

Prime Medicine has reported EPS (Basic) for 6 years, with the latest figure at -$0.28 in Q1 2026.

  • For the quarter ending Q1 2026, EPS (Basic) rose 30.0% year-over-year to -$0.28; the trailing twelve-month figure through Mar 2026 stood at -$1.25 (up 22.36% YoY), and the FY2025 full-year result was -$1.35, up 18.18% from the prior year.
  • EPS (Basic) for Q1 2026 stood at -$0.28, down from -$0.24 in the prior quarter.
  • The five-year high for EPS (Basic) was $0.72 in Q4 2022, with the low at -$1.76 in Q2 2022.
  • Historically, EPS (Basic) has averaged -$0.57 across 5 years, with a median of -$0.44 in 2023.
  • Annual changes were most pronounced in 2022 — EPS (Basic) surged 116.18% — and 2023, when it slumped 200.0%.
  • Prime Medicine's EPS (Basic) stood at $0.72 in 2022, then tumbled by 200.0% to -$0.72 in 2023, then jumped by 56.94% to -$0.31 in 2024, then grew by 22.58% to -$0.24 in 2025, then fell by 16.67% to -$0.28 in 2026.
  • The last three EPS (Basic) figures came in at -$0.28 (Q1 2026), -$0.24 (Q4 2025), and -$0.32 (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EPS (Basic) (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -0.68
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 3.06
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 0.00
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - 0.00
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - 0.00
7 Psyence Biomedical 212.16 Bn 212.16 Bn - 0.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 4.06
9 Abivax 91.96 Bn 91.96 Bn - -0.06
10 Prime Medicine 572.02 Mn 572.02 Mn - -0.28

Historic Data

Download Data
DateValue
Mar 31, 2026 -0.28
Dec 31, 2025 -0.24
Sep 30, 2025 -0.32
Jun 30, 2025 -0.41
Mar 31, 2025 -0.40
Dec 31, 2024 -0.31
Sep 30, 2024 -0.44
Jun 30, 2024 -0.46
Mar 31, 2024 -0.44
Dec 31, 2023 -0.72
Sep 30, 2023 -0.55
Jun 30, 2023 -0.47
Mar 31, 2023 -0.44
Dec 31, 2022 0.72
Sep 30, 2022 -1.61
Jun 30, 2022 -1.76
Mar 31, 2022 -1.58
Dec 31, 2021 -4.45
Sep 30, 2021 -1.52