Prime Medicine (PRME) EPS (Basic) (2021 - 2026)
Prime Medicine posted quarterly EPS (Basic) of -$0.28 for Q1 2026, up 30.0% year-on-year from -$0.22 in Q1 2025, and down 16.67% on a QoQ basis from -$0.24 in Q4 2025.
Prime Medicine (PRME) has 6 years of EPS (Basic) data on file, last reported at -$0.28 in Q1 2026.
- For the quarter ending Q1 2026, EPS (Basic) rose 30.0% year-over-year to -$0.28; the trailing twelve-month figure through Mar 2026 stood at -$1.25 (up 22.36% YoY), and the FY2025 full-year result was -$1.35, up 18.18% from the prior year.
- EPS (Basic) for Q1 2026 stood at -$0.28, down from -$0.24 in the prior quarter.
- Across five years, EPS (Basic) topped out at $0.72 in Q4 2022 and bottomed at -$1.76 in Q2 2022.
- The 5-year median for EPS (Basic) is -$0.44 (2023), against an average of -$0.57.
- The widest annual swing landed in 2022, when EPS (Basic) surged 116.18%; it then plunged 200.0% in 2023.
- A 5-year view of EPS (Basic) shows it stood at $0.72 in 2022, then slumped by 200.0% to -$0.72 in 2023, then surged by 56.94% to -$0.31 in 2024, then increased by 22.58% to -$0.24 in 2025, then retreated by 16.67% to -$0.28 in 2026.
- The last three EPS (Basic) figures came in at -$0.28 (Q1 2026), -$0.24 (Q4 2025), and -$0.32 (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EPS (Basic) (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | 3.06 |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | 0.00 |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | 0.00 |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 4.06 |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | 0.00 |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 6.99 |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 1.55 |
| 10 | Prime Medicine | 601.24 Mn | 601.24 Mn | - | -0.28 |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -0.28 |
| Dec 31, 2025 | -0.24 |
| Sep 30, 2025 | -0.32 |
| Jun 30, 2025 | -0.41 |
| Mar 31, 2025 | -0.40 |
| Dec 31, 2024 | -0.31 |
| Sep 30, 2024 | -0.44 |
| Jun 30, 2024 | -0.46 |
| Mar 31, 2024 | -0.44 |
| Dec 31, 2023 | -0.72 |
| Sep 30, 2023 | -0.55 |
| Jun 30, 2023 | -0.47 |
| Mar 31, 2023 | -0.44 |
| Dec 31, 2022 | 0.72 |
| Sep 30, 2022 | -1.61 |
| Jun 30, 2022 | -1.76 |
| Mar 31, 2022 | -1.58 |
| Dec 31, 2021 | -4.45 |
| Sep 30, 2021 | -1.52 |