Prime Medicine (PRME) Other Gross PP&E Adjustments (2021 - 2026)

Prime Medicine posted quarterly Other Gross PP&E Adjustments of -$82.2 million for Q1 2026, down 347.28% year-on-year from $33.3 million in Q1 2025, and up 14.78% on a QoQ basis from -$96.5 million in Q4 2025.

Prime Medicine (PRME) has 6 years of Other Gross PP&E Adjustments data on file, last reported at -$82.2 million in Q1 2026.

  • For the quarter ending Q1 2026, Other Gross PP&E Adjustments fell 347.28% year-over-year to -$82.2 million; the trailing twelve-month figure through Mar 2026 stood at -$82.2 million (down 347.28% YoY), and the FY2025 full-year result was -$96.5 million, down 536.45% from the prior year.
  • Other Gross PP&E Adjustments for Q1 2026 stood at -$82.2 million, up from -$96.5 million in the prior quarter.
  • Across five years, Other Gross PP&E Adjustments topped out at $33.3 million in Q1 2025 and bottomed at -$96.5 million in Q4 2025.
  • The 5-year median for Other Gross PP&E Adjustments is -$12.2 million (2024), against an average of -$21.4 million.
  • Peak annual rise in Other Gross PP&E Adjustments reached 2515.33% in 2024, while the deepest fall reached 881.06% in 2024.
  • A 5-year view of Other Gross PP&E Adjustments shows it stood at -$7.8 million in 2022, then surged by 288.18% to $14.7 million in 2023, then plunged by 202.93% to -$15.2 million in 2024, then plunged by 536.45% to -$96.5 million in 2025, then grew by 14.78% to -$82.2 million in 2026.
  • The last three Other Gross PP&E Adjustments figures came in at -$82.2 million (Q1 2026), -$96.5 million (Q4 2025), and -$77.3 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Other Gross PP&E Adjustments (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -83,048.00
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -60,691.22
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -285.20 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -892,000.00
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn -1.69 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn -
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn -189.30 Mn
10 Prime Medicine 601.24 Mn 601.24 Mn - -82.23 Mn

Historic Data

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DateValue
Mar 31, 2026 -82.23 Mn
Mar 31, 2026 -82.23 Mn
Dec 31, 2025 -96.49 Mn
Dec 31, 2025 -96.49 Mn
Sep 30, 2025 -77.27 Mn
Sep 30, 2025 -77.27 Mn
Jun 30, 2025 -79.70 Mn
Jun 30, 2025 -79.70 Mn
Mar 31, 2025 33.25 Mn
Mar 31, 2025 33.25 Mn
Dec 31, 2024 -15.16 Mn
Dec 31, 2024 -15.16 Mn
Sep 30, 2024 -14.20 Mn
Sep 30, 2024 -14.20 Mn
Jun 30, 2024 22.85 Mn
Jun 30, 2024 22.85 Mn
Mar 31, 2024 -12.18 Mn
Mar 31, 2024 -12.18 Mn
Dec 31, 2023 14.73 Mn
Dec 31, 2023 14.73 Mn
Sep 30, 2023 11.00 Mn
Sep 30, 2023 11.00 Mn
Jun 30, 2023 -946,000.00
Jun 30, 2023 -946,000.00
Mar 31, 2023 -1.24 Mn
Mar 31, 2023 -1.24 Mn
Dec 31, 2022 -7.83 Mn
Dec 31, 2022 -7.83 Mn
Sep 30, 2022 -15.42 Mn
Sep 30, 2022 -15.42 Mn
Dec 31, 2021 -5.20 Mn
Dec 31, 2021 -5.20 Mn