Prime Medicine (PRME) Change in Cash (2021 - 2026)

Prime Medicine (PRME) has 6 years of Change in Cash data on file, last reported at $1.1 million in Q1 2026.

• For the quarter ending Q1 2026, Change in Cash rose 101.19% year-over-year to $1.1 million; the trailing twelve-month figure through Mar 2026 stood at -$28.1 million (down 1537.11% YoY), and the FY2025 full-year result was -$119.8 million, down 184.69% from the prior year.
• Change in Cash for Q1 2026 stood at $1.1 million, up from -$8.4 million in the prior quarter.
• Across five years, Change in Cash topped out at $139.7 million in Q4 2022 and bottomed at -$90.6 million in Q1 2025.
• The 5-year median for Change in Cash is -$12.9 million (2023), against an average of -$7.1 million.
• The widest annual swing landed in 2022, when Change in Cash soared 6691.46%; it then tumbled 272.28% in 2025.
• A 5-year view of Change in Cash shows it stood at $139.7 million in 2022, then plunged by 101.71% to -$2.4 million in 2023, then surged by 2804.36% to $64.5 million in 2024, then tumbled by 112.97% to -$8.4 million in 2025, then jumped by 112.84% to $1.1 million in 2026.
• The last three Change in Cash figures came in at $1.1 million (Q1 2026), -$8.4 million (Q4 2025), and $17.6 million (Q3 2025), per Business Quant data.

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