Prime Medicine (PRME) Change in Cash (2021 - 2026)
Prime Medicine's Change in Cash was -$16.66 million in Q2 2026, compared with -$38.44 million a year earlier.
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Analysis
Prime Medicine (PRME) Change in Cash (2021 - 2026) Analysis & Trends
On a trailing twelve-month basis, Prime Medicine's Change in Cash was -$6.35 million through Jun 30, 2026; for FY2025, it was -$119.82 million.
- In earlier years, Change in Cash was $141.47 million in FY2024, -$146.05 million in FY2023, $2.57 million in FY2022 (-98.4%) and $161.57 million in FY2021 (+470.4%).
- Quarterly Change in Cash has moved between -$90.6 million (Q1 2025) and $139.67 million (Q4 2022) over five years.
- Per Business Quant data, PRME's Change in Cash in the three quarters before Q2 2026 was $1.07 million (Q1 2026), -$8.36 million (Q4 2025) and $17.59 million (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change in Cash (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 638.12 Bn | 556.64 Bn | 17.26 Bn | -1.27 Bn |
| 2 | AbbVie | 462.60 Bn | 435.75 Bn | 12.70 Bn | -2.82 Bn |
| 3 | Merck | 358.70 Bn | 313.13 Bn | 12.21 Bn | 1.49 Bn |
| 4 | Novartis Ag | 272.16 Bn | 228.03 Bn | 11.24 Bn | 739.00 Mn |
| 5 | Astrazeneca | 250.36 Bn | 223.92 Bn | 12.86 Bn | -2.64 Bn |
| 6 | Amgen | 227.87 Bn | 183.27 Bn | 7.24 Bn | 1.95 Bn |
| 7 | Gilead Sciences | 184.97 Bn | 159.08 Bn | 6.22 Bn | -4.45 Bn |
| 8 | Pfizer | 162.61 Bn | 109.56 Bn | 10.94 Bn | -727.00 Mn |
| 9 | Vertex Pharmaceuticals | 132.45 Bn | 104.46 Bn | 2.84 Bn | 649.20 Mn |
| 10 | Prime Medicine | 553.06 Mn | 553.06 Mn | - | -16.66 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -16.66 Mn |
| Mar 31, 2026 | 1.07 Mn |
| Dec 31, 2025 | -8.36 Mn |
| Sep 30, 2025 | 17.59 Mn |
| Jun 30, 2025 | -38.44 Mn |
| Mar 31, 2025 | -90.60 Mn |
| Dec 31, 2024 | 64.50 Mn |
| Sep 30, 2024 | 62.94 Mn |
| Jun 30, 2024 | -38.56 Mn |
| Mar 31, 2024 | 52.59 Mn |
| Dec 31, 2023 | -2.39 Mn |
| Sep 30, 2023 | -76.62 Mn |
| Jun 30, 2023 | -12.89 Mn |
| Mar 31, 2023 | -54.16 Mn |
| Dec 31, 2022 | 139.67 Mn |
| Sep 30, 2022 | -44.29 Mn |
| Jun 30, 2022 | -71.64 Mn |
| Mar 31, 2022 | -21.17 Mn |
| Dec 31, 2021 | -2.12 Mn |
API Access
Prime Medicine Change in Cash API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=change-in-cash&ticker=PRME&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "change-in-cash", "ticker": "PRME", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=change-in-cash&ticker=PRME&period=max&api_key=YOUR_API_KEY");
const data = await res.json();