Prime Medicine (PRME) Return on Equity (2022 - 2026)

Prime Medicine posted quarterly Return on Equity of 0.02% for Q1 2026, little changed year-on-year from 0.02% in Q1 2025, and down 41.51% on a QoQ basis from 0.01% in Q4 2025.

Prime Medicine (PRME) has 5 years of Return on Equity data on file, last reported at 0.02% in Q1 2026.

  • For the quarter ending Q1 2026, Return on Equity changed 0.0% year-over-year to 0.02%; the trailing twelve-month figure through Mar 2026 stood at 0.02% (changed 0.0% YoY), and the FY2025 full-year result was 0.01%, changed 0.0% from the prior year.
  • Return on Equity for Q1 2026 stood at 0.02%, down from 0.01% in the prior quarter.
  • Across five years, Return on Equity topped out at 0.01% in Q2 2022 and bottomed at 0.03% in Q4 2022.
  • The 5-year median for Return on Equity is 0.01% (2024), against an average of 0.01%.
  • Peak annual rise in Return on Equity reached 1 bps in 2023, while the deepest fall reached 1 bps in 2023.
  • A 5-year view of Return on Equity shows it stood at 0.03% in 2022, then jumped by 54 bps to 0.01% in 2023, then climbed by 6 bps to 0.01% in 2024, then dropped by 27 bps to 0.01% in 2025, then sank by 42 bps to 0.02% in 2026.
  • The last three Return on Equity figures came in at 0.02% (Q1 2026), 0.01% (Q4 2025), and 0.02% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROE (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -0.04%
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -0.01%
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 0.00%
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 0.00%
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 0.01%
10 Prime Medicine 601.24 Mn 601.24 Mn - -0.02%

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 -0.02%
Dec 31, 2025 -0.01%
Sep 30, 2025 -0.02%
Jun 30, 2025 -0.02%
Mar 31, 2025 -0.02%
Dec 31, 2024 -0.01%
Sep 30, 2024 -0.01%
Jun 30, 2024 -0.01%
Mar 31, 2024 -0.01%
Dec 31, 2023 -0.01%
Sep 30, 2023 -0.01%
Jun 30, 2023 -0.01%
Mar 31, 2023 0.00%
Dec 31, 2022 -0.03%
Sep 30, 2022 0.01%
Jun 30, 2022 0.01%