Prime Medicine (PRME) Return on Equity (2022 - 2025)

Prime Medicine (PRME) has disclosed Return on Equity for 4 consecutive years, with 1.45% as the latest value for Q4 2025.

  • For the quarter ending Q4 2025, Return on Equity fell 31.0% year-over-year to 1.45%, compared with a TTM value of 1.45% through Dec 2025, down 31.0%, and an annual FY2025 reading of 1.49%, down 12.0% over the prior year.
  • Return on Equity was 1.45% for Q4 2025 at Prime Medicine, up from 1.79% in the prior quarter.
  • Across five years, Return on Equity topped out at 0.7% in Q2 2022 and bottomed at 2.61% in Q4 2022.
  • Average Return on Equity over 4 years is 1.05%, with a median of 1.14% recorded in 2024.
  • Peak annual rise in Return on Equity hit 140bps in 2023, while the deepest fall reached -149bps in 2023.
  • Year by year, Return on Equity stood at 2.61% in 2022, then surged by 54bps to 1.21% in 2023, then increased by 6bps to 1.14% in 2024, then fell by -27bps to 1.45% in 2025.
  • Business Quant data shows Return on Equity for PRME at 1.45% in Q4 2025, 1.79% in Q3 2025, and 2.38% in Q2 2025.