Prime Medicine (PRME) EBITDA Margin (2024 - 2026)
Prime Medicine (PRME) posted EBITDA Margin of 5917.52% for Q1 2026, down 2.02% on a QoQ basis from 5800.48% in Q4 2025, and down 231422.0% year-over-year from N/an in Q1 2025.
Prime Medicine (PRME) EBITDA Margin (2024 - 2026) Analysis & Trends
Prime Medicine's EBITDA Margin history runs 3 years deep, the most recent figure standing at 5917.52% for Q1 2026.
- Quarterly EBITDA Margin fell 231422.0% year-over-year to 5917.52% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 5121.76% (up 24792.0% YoY) and the FY2025 annual result came in at 4498.06%, up 228930.0% from the prior year.
- EBITDA Margin was 5917.52% for Q1 2026 at Prime Medicine, down from 5800.48% in the prior quarter.
- Across five years, EBITDA Margin topped out at 2025.74% in Q4 2024 and bottomed at 25948.33% in Q3 2024.
- A 3-year average of 7583.5% and a median of 5293.83% in 2025 frame the typical range for EBITDA Margin.
- Peak annual rise in EBITDA Margin reached 2154237 bps in 2025, while the deepest fall reached 377473 bps in 2025.
- Prime Medicine's EBITDA Margin stood at 2025.74% in 2024, then plunged by 186 bps to 5800.48% in 2025, then dropped by 2 bps to 5917.52% in 2026.
- Business Quant data shows PRME's EBITDA Margin at 5917.52% in Q1 2026, 5800.48% in Q4 2025, and 4405.96% in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | - |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 16.51% |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | - |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 38.10% |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 17.83% |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 31.68% |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | - |
| 10 | Prime Medicine | 525.98 Mn | 525.98 Mn | - | -5,917.52% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -5,917.52% |
| Dec 31, 2025 | -5,800.48% |
| Sep 30, 2025 | -4,405.96% |
| Jun 30, 2025 | -4,787.17% |
| Mar 31, 2025 | -3,603.30% |
| Dec 31, 2024 | -2,025.74% |
| Sep 30, 2024 | -25,948.33% |
| Mar 31, 2024 | -8,179.53% |