Prime Medicine, Inc. (PRME) Insider Ownership

Historic Ownership Trends

Data spanning the past 90 days through December 12, 2025 reveals that Prime Medicine's three principal insider shareholders consist of Director Robert Nelsen (6.13Mn shares), TenPercentOwner Venture Partners X, Llc Arch (6.13Mn shares), TenPercentOwner Venture Partners Xii, Llc Arch (6.13Mn shares).

Top Direct Holders

Insider ownership data is derived from the last 60 months of Form 4 SEC filings.
Holder Position Shares Report Date
David R. Liu 20,240,945 01 Jul, 2025
Venture Partners X, Llc Arch 6,128,297 01 Aug, 2025
Robert Nelsen 6,128,297 01 Aug, 2025
Venture Partners Xii, Llc Arch 6,128,297 01 Aug, 2025
Thomas Cahill 5,305,679 26 Oct, 2022
Llc Fmr 4,228,589 26 Oct, 2022
2021 Gp, L.L.C. Gv 3,262,440 05 Aug, 2025
Keith Michael Gottesdiener 2,993,096 07 Jun, 2024
Allan Reine Chief Executive Officer 125,000 22 May, 2025
Ann L. Lee Chief Technical Officer 100,000 22 May, 2025
Richard Brudnick Chief Business Officer 20,000 22 May, 2025

* Please note that the shares above only reflect shares from the fund portfolio and the institutional portfolio. Shares from the personal portfolio are excluded from this Institutional Ownership Page. See these insiders' latest transactions here on Insider Page.

Recent Insider Transactions

Detailed insider trading activity based on Form 4 SEC filings.
Download Data
Transaction Date Insider Name Security Class Transaction Type Shares Traded Price Shares Remaining Ownership Code
01 Aug, 2025 Venture Partners X, Llc Arch Common Stock A 3,030,300 $3.30 6,128,297 I P
01 Aug, 2025 Venture Partners Xii, Llc Arch Common Stock A 3,030,300 $3.30 6,128,297 I P
01 Aug, 2025 Robert Nelsen Common Stock A 3,030,300 $3.30 6,128,297 I P
01 Aug, 2025 2021 Gp, L.L.C. Gv Common Stock A 1,500,000 $3.30 3,262,440 I P
30 Jun, 2025 David R. Liu Common Stock A 21,000 $2.52 20,240,945 D P
23 Jun, 2025 David R. Liu Common Stock A 21,000 $2.16 20,219,945 D P
16 Jun, 2025 David R. Liu Common Stock A 21,000 $1.49 20,198,945 D P
11 Jun, 2025 David R. Liu Common Stock A 21,000 $1.60 20,177,945 D P
11 Jun, 2025 David R. Liu - - 20,177,945 D
21 May, 2025 Ann L. Lee Common Stock A 100,000 $1.13 100,000 D P
21 May, 2025 Ann L. Lee - - 100,000 D
21 May, 2025 Allan Reine Common Stock A 125,000 $1.18 125,000 D P
20 May, 2025 Richard Brudnick Common Stock A 20,000 $1.19 20,000 D P
20 May, 2025 Richard Brudnick - - 20,000 D
08 Oct, 2024 Keith Michael Gottesdiener Common Stock D 226,925 $0.00 50,241 I G
08 Oct, 2024 Keith Michael Gottesdiener - - 50,241 I
08 Oct, 2024 Keith Michael Gottesdiener - - 682,259 I
08 Oct, 2024 Keith Michael Gottesdiener Common Stock A 226,925 $0.00 682,259 I G
05 Jun, 2024 Keith Michael Gottesdiener Common Stock D 250,000 $0.00 2,310,837 D G
05 Jun, 2024 Keith Michael Gottesdiener - - 2,310,837 D