Prime Medicine's top three insider shareholders as of May 14, 2026 are David R. Liu (TenPercentOwner, 20.24Mn shares), Robert Nelsen (Director, 12.27Mn shares), Venture Partners X, Llc Arch (TenPercentOwner, 12.26Mn shares).
| Holder | Position | Shares (Direct) | Shares (Indirect) | Report Date |
|---|---|---|---|---|
| David R. Liu | - | 20,240,945 | 0 | 01 Jul, 2025 |
| Robert Nelsen | - | 0 | 12,272,674 | 26 Oct, 2022 |
| Venture Partners X, Llc Arch | - | 0 | 12,256,594 | 26 Oct, 2022 |
| Venture Partners X, Llc Arch | - | 0 | 12,256,594 | 26 Oct, 2022 |
| 2019 Gp, L.L.C. Gv | - | 0 | 10,100,058 | 22 Jun, 2023 |
| 2019 Gp, L.L.C. Gv | - | 0 | 10,100,058 | 22 Jun, 2023 |
| 2019 Gp, L.L.C. Gv | - | 0 | 10,100,058 | 22 Jun, 2023 |
| 2019 Gp, L.L.C. Gv | - | 0 | 10,100,058 | 22 Jun, 2023 |
| 2019 Gp, L.L.C. Gv | - | 0 | 10,100,058 | 22 Jun, 2023 |
| Llc Fmr | - | 0 | 8,462,946 | 26 Oct, 2022 |
| Robert Nelsen | - | 0 | 6,230,300 | 01 Aug, 2025 |
| Venture Partners X, Llc Arch | - | 0 | 6,230,300 | 01 Aug, 2025 |
| Venture Partners Xii, Llc Arch | - | 0 | 6,230,300 | 01 Aug, 2025 |
| Venture Partners Xii, Llc Arch | - | 0 | 6,230,300 | 01 Aug, 2025 |
| Venture Partners Xii, Llc Arch | - | 0 | 6,230,300 | 01 Aug, 2025 |
| Venture Partners X, Llc Arch | - | 0 | 6,230,300 | 01 Aug, 2025 |
| Venture Partners Xii, Llc Arch | - | 0 | 6,230,300 | 01 Aug, 2025 |
| Thomas Cahill | - | 0 | 5,305,679 | 26 Oct, 2022 |
| 2021 Gp, L.L.C. Gv | - | 0 | 3,262,440 | 05 Aug, 2025 |
| 2021 Gp, L.L.C. Gv | - | 0 | 3,262,440 | 05 Aug, 2025 |
| 2021 Gp, L.L.C. Gv | - | 0 | 3,262,440 | 05 Aug, 2025 |
| 2021 Gp, L.L.C. Gv | - | 0 | 3,262,440 | 05 Aug, 2025 |
| 2021 Gp, L.L.C. Gv | - | 0 | 3,262,440 | 05 Aug, 2025 |
| Keith Michael Gottesdiener | - | 2,310,837 | 0 | 07 Jun, 2024 |
| 2019 Gp, L.L.C. Gv | - | 0 | 1,762,440 | 26 Oct, 2022 |
| 2019 Gp, L.L.C. Gv | - | 0 | 1,762,440 | 26 Oct, 2022 |
| 2019 Gp, L.L.C. Gv | - | 0 | 1,762,440 | 26 Oct, 2022 |
| 2019 Gp, L.L.C. Gv | - | 0 | 1,762,440 | 26 Oct, 2022 |
| 2019 Gp, L.L.C. Gv | - | 0 | 1,762,440 | 26 Oct, 2022 |
| Keith Michael Gottesdiener | - | 0 | 732,500 | 10 Oct, 2024 |
| Allan Reine | Chief Executive Officer | 125,000 | 0 | 22 May, 2025 |
| Allan Reine | Chief Executive Officer | 125,000 | 0 | 22 May, 2025 |
| Ann L. Lee | Chief Technical Officer | 100,000 | 0 | 22 May, 2025 |
| Richard Brudnick | Chief Business Officer | 20,000 | 0 | 22 May, 2025 |
* Please note that the shares above only reflect shares from the fund portfolio and the institutional portfolio. Shares from the personal portfolio are excluded from this Institutional Ownership Page. See these insiders' latest transactions here on Insider Page.
| Transaction Date | Insider Name | Security Class | Transaction Type | Shares Traded | Price | Shares Remaining | Ownership | Code |
|---|---|---|---|---|---|---|---|---|
| 16 Apr, 2026 | Svetlana Ni Makhni | Stock Option (right to buy) | A | 800,000 | $0.00 | 800,000 | D | A |
| 26 Feb, 2026 | Allan Reine | Stock Option (right to buy) | A | 1,300,000 | $0.00 | 1,300,000 | D | A |
| 26 Feb, 2026 | Allan Reine | Stock Option (right to buy) | A | 1,300,000 | $0.00 | 1,300,000 | D | A |
| 23 Feb, 2026 | Carman Alenson | Stock Option (right to buy) | A | 140,000 | $0.00 | 140,000 | D | A |
| 23 Feb, 2026 | Ann L. Lee | Stock Option (right to buy) | A | 375,000 | $0.00 | 375,000 | D | A |
| 01 Aug, 2025 | Allan Reine | Stock Option (right to buy) | D | 850,000 | - | 0 | D | D |
| 01 Aug, 2025 | David P Schenkein | Stock Option (right to buy) | D | 39,062 | - | 0 | D | D |
| 01 Aug, 2025 | Ann L. Lee | Stock Option (right to buy) | D | 180,995 | - | 0 | D | D |
| 01 Aug, 2025 | Jeffrey D Marrazzo | Stock Option (right to buy) | D | 92,000 | - | 0 | D | D |
| 01 Aug, 2025 | Kaye I Foster-Cheek | Stock Option (right to buy) | D | 13,510 | - | 0 | D | D |
| 01 Aug, 2025 | Thomas Cahill | Stock Option (right to buy) | D | 39,062 | - | 0 | D | D |
| 01 Aug, 2025 | 2021 Gp, L.L.C. Gv | Common Stock | A | 1,500,000 | $3.30 | 3,262,440 | I | P |
| 01 Aug, 2025 | Wendy Chung | Stock Option (right to buy) | D | 13,510 | - | 0 | D | D |
| 01 Aug, 2025 | Robert Nelsen | Stock Option (right to buy) | D | 39,062 | - | 0 | D | D |
| 01 Aug, 2025 | Michael Aaron Kelly | Stock Option (right to buy) | D | 13,510 | - | 0 | D | D |
| 01 Aug, 2025 | 2021 Gp, L.L.C. Gv | Common Stock | A | 1,500,000 | $3.30 | 3,262,440 | I | P |
| 01 Aug, 2025 | Carman Alenson | Stock Option (right to buy) | D | 16,083 | - | 0 | D | D |
| 01 Aug, 2025 | 2021 Gp, L.L.C. Gv | Common Stock | A | 1,500,000 | $3.30 | 3,262,440 | I | P |
| 01 Aug, 2025 | 2021 Gp, L.L.C. Gv | Common Stock | A | 1,500,000 | $3.30 | 3,262,440 | I | P |
| 01 Aug, 2025 | Allan Reine | Stock Option (right to buy) | D | 850,000 | - | 0 | D | D |