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Prime Medicine (PRME) Net Income (2021 - 2025)

Prime Medicine filings provide 5 years of Net Income readings, the most recent being -$47.5 million for Q4 2025.

  • On a quarterly basis, Net Income fell 12.42% to -$47.5 million in Q4 2025 year-over-year; TTM through Dec 2025 was -$204.8 million, a 4.57% decrease, with the full-year FY2025 number at -$204.2 million, down 4.25% from a year prior.
  • Net Income hit -$47.5 million in Q4 2025 for Prime Medicine, up from -$52.8 million in the prior quarter.
  • In the past five years, Net Income ranged from a high of -$16.4 million in Q3 2021 to a low of -$65.6 million in Q4 2023.
  • Median Net Income over the past 5 years was -$46.6 million (2024), compared with a mean of -$44.4 million.
  • The widest YoY moves for Net Income: up 37.56% in 2022, down 78.83% in 2022.
  • Prime Medicine's Net Income stood at -$62.9 million in 2021, then surged by 37.56% to -$39.3 million in 2022, then tumbled by 67.1% to -$65.6 million in 2023, then surged by 35.6% to -$42.3 million in 2024, then decreased by 12.42% to -$47.5 million in 2025.
  • The last three reported values for Net Income were -$47.5 million (Q4 2025), -$52.8 million (Q3 2025), and -$52.6 million (Q2 2025) per Business Quant data.