Prime Medicine (PRME) EBITDA (2021 - 2026)
Prime Medicine (PRME) posted EBITDA of -$41.5 million for Q2 2026, compared with -$51.51 million a year earlier.
Powered by 
Analysis
Prime Medicine (PRME) EBITDA (2021 - 2026) Analysis & Trends
For the trailing twelve months through Jun 30, 2026, EBITDA at Prime Medicine was -$189.12 million; for FY2025, it came in at -$201.03 million.
- In prior years, Prime Medicine's EBITDA was -$196.34 million in FY2024, -$200.14 million in FY2023, -$114.32 million in FY2022 and -$83.87 million in FY2021.
- The Q2 2026 figure stands as the highest quarterly EBITDA since Q1 2023.
- According to Business Quant data, EBITDA for the three prior quarters was -$48.8 million (Q1 2026), -$46.73 million (Q4 2025) and -$52.09 million (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 9.10 Bn |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 8.33 Bn |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | 999.00 Mn |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | - |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 5.09 Bn |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 4.63 Bn |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -9.70 Bn |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 5.89 Bn |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 1.30 Bn |
| 10 | Prime Medicine | 520.52 Mn | 520.52 Mn | - | -41.50 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -41.50 Mn |
| Mar 31, 2026 | -48.80 Mn |
| Dec 31, 2025 | -46.73 Mn |
| Sep 30, 2025 | -52.09 Mn |
| Jun 30, 2025 | -51.51 Mn |
| Mar 31, 2025 | -50.69 Mn |
| Dec 31, 2024 | -42.51 Mn |
| Sep 30, 2024 | -52.67 Mn |
| Jun 30, 2024 | -54.13 Mn |
| Mar 31, 2024 | -47.03 Mn |
| Dec 31, 2023 | -66.80 Mn |
| Sep 30, 2023 | -50.22 Mn |
| Jun 30, 2023 | -44.14 Mn |
| Mar 31, 2023 | -38.98 Mn |
| Dec 31, 2022 | -37.82 Mn |
| Sep 30, 2022 | -31.02 Mn |
| Jun 30, 2022 | -25.88 Mn |
| Mar 31, 2022 | -19.61 Mn |
| Dec 31, 2021 | -59.82 Mn |
| Sep 30, 2021 | -10.23 Mn |
API Access
Prime Medicine EBITDA API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebitda&ticker=PRME&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebitda", "ticker": "PRME", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=ebitda&ticker=PRME&period=max&api_key=YOUR_API_KEY");
const data = await res.json();