Prime Medicine (PRME) Change in Accured Expenses (2021 - 2026)
Prime Medicine posted quarterly Change in Accured Expenses of -$4.5 million for Q1 2026, up 32.35% year-on-year from -$3.4 million in Q1 2025, and down 381.38% on a QoQ basis from $1.6 million in Q4 2025.
Prime Medicine (PRME) has 6 years of Change in Accured Expenses data on file, last reported at -$4.5 million in Q1 2026.
- For the quarter ending Q1 2026, Change in Accured Expenses rose 32.35% year-over-year to -$4.5 million; the trailing twelve-month figure through Mar 2026 stood at $993000.0 (up 394.66% YoY), and the FY2025 full-year result was -$1.2 million, down 162.94% from the prior year.
- Change in Accured Expenses for Q1 2026 stood at -$4.5 million, down from $1.6 million in the prior quarter.
- Across five years, Change in Accured Expenses topped out at $5.9 million in Q3 2024 and bottomed at -$33.3 million in Q1 2022.
- The 5-year median for Change in Accured Expenses is $608000.0 (2023), against an average of -$1.6 million.
- Peak annual rise in Change in Accured Expenses reached 1211.11% in 2025, while the deepest fall reached 118.06% in 2025.
- A 5-year view of Change in Accured Expenses shows it stood at $4.1 million in 2022, then slumped by 38.53% to $2.5 million in 2023, then plunged by 105.73% to -$144000.0 in 2024, then jumped by 1211.11% to $1.6 million in 2025, then plunged by 381.38% to -$4.5 million in 2026.
- The last three Change in Accured Expenses figures came in at -$4.5 million (Q1 2026), $1.6 million (Q4 2025), and -$1.1 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change in Accured Expenses (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | - |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | - |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | 931,000.00 |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 70.50 Mn |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 107.70 Mn |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | -176.03 Mn |
| 10 | Prime Medicine | 601.24 Mn | 601.24 Mn | - | -4.50 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -4.50 Mn |
| Mar 31, 2026 | -4.50 Mn |
| Dec 31, 2025 | 1.60 Mn |
| Dec 31, 2025 | 1.60 Mn |
| Sep 30, 2025 | -1.07 Mn |
| Sep 30, 2025 | -1.07 Mn |
| Jun 30, 2025 | 4.97 Mn |
| Jun 30, 2025 | 4.97 Mn |
| Mar 31, 2025 | -6.66 Mn |
| Mar 31, 2025 | -6.66 Mn |
| Dec 31, 2024 | -144,000.00 |
| Dec 31, 2024 | -144,000.00 |
| Sep 30, 2024 | 5.93 Mn |
| Sep 30, 2024 | 5.93 Mn |
| Jun 30, 2024 | 536,000.00 |
| Jun 30, 2024 | 536,000.00 |
| Mar 31, 2024 | -4.48 Mn |
| Mar 31, 2024 | -4.48 Mn |
| Dec 31, 2023 | 2.51 Mn |
| Dec 31, 2023 | 2.51 Mn |
| Sep 30, 2023 | 2.68 Mn |
| Sep 30, 2023 | 2.68 Mn |
| Jun 30, 2023 | 608,000.00 |
| Jun 30, 2023 | 608,000.00 |
| Mar 31, 2023 | -4.05 Mn |
| Mar 31, 2023 | -4.05 Mn |
| Dec 31, 2022 | 4.09 Mn |
| Dec 31, 2022 | 4.09 Mn |
| Sep 30, 2022 | 890,000.00 |
| Sep 30, 2022 | 890,000.00 |
| Jun 30, 2022 | 2.47 Mn |
| Jun 30, 2022 | 2.47 Mn |
| Mar 31, 2022 | -33.32 Mn |
| Mar 31, 2022 | -33.32 Mn |
| Dec 31, 2021 | 33.31 Mn |
| Dec 31, 2021 | 33.31 Mn |