Prime Medicine (PRME) Gains from Investment Securities (2022 - 2025)
Prime Medicine (PRME) reported Gains from Investment Securities of -$83.3 million for Q4 2025, down 138975.0% on a YoY basis from N/an in Q4 2024, and down 197.66% quarter-over-quarter from $85.3 million in Q3 2025.
Prime Medicine (PRME) Gains from Investment Securities (2022 - 2025) Analysis & Trends
Prime Medicine has reported Gains from Investment Securities for 4 years, with the latest figure at -$83.3 million in Q4 2025.
- For the quarter ending Q4 2025, Gains from Investment Securities fell 138975.0% year-over-year to -$83.3 million; the trailing twelve-month figure through Mar 2026 stood at $1.5 million (up 103.2% YoY), and the FY2025 full-year result was $432000.0, up 189.26% from the prior year.
- Gains from Investment Securities for Q4 2025 stood at -$83.3 million, down from $85.3 million in the prior quarter.
- The five-year high for Gains from Investment Securities was $85.3 million in Q3 2025, with the low at -$83.3 million in Q4 2025.
- Historically, Gains from Investment Securities has averaged -$586285.7 across 4 years, with a median of -$244000.0 in 2022.
- Annual changes were most pronounced in 2024 — Gains from Investment Securities soared 2741.68% — and 2025, when it sank 138975.0%.
- Prime Medicine's Gains from Investment Securities stood at -$36.7 million in 2022, then soared by 108.14% to $3.0 million in 2023, then slumped by 97.99% to $60000.0 in 2024, then slumped by 138975.0% to -$83.3 million in 2025.
- The last three Gains from Investment Securities figures came in at -$83.3 million (Q4 2025), $85.3 million (Q3 2025), and -$505000.0 (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - |
| 10 | Prime Medicine | 572.02 Mn | 572.02 Mn | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -83.33 Mn |
| Dec 31, 2025 | -83.33 Mn |
| Sep 30, 2025 | 85.32 Mn |
| Sep 30, 2025 | 85.32 Mn |
| Jun 30, 2025 | -505,000.00 |
| Jun 30, 2025 | -505,000.00 |
| Mar 31, 2025 | -1.06 Mn |
| Mar 31, 2025 | -1.06 Mn |
| Dec 31, 2024 | 60,000.00 |
| Dec 31, 2024 | 60,000.00 |
| Sep 30, 2024 | -45.48 Mn |
| Sep 30, 2024 | -45.48 Mn |
| Mar 31, 2024 | 44.94 Mn |
| Mar 31, 2024 | 44.94 Mn |
| Dec 31, 2023 | 2.99 Mn |
| Dec 31, 2023 | 2.99 Mn |
| Sep 30, 2023 | -6.28 Mn |
| Sep 30, 2023 | -6.28 Mn |
| Jun 30, 2023 | 4.97 Mn |
| Jun 30, 2023 | 4.97 Mn |