Prime Medicine (PRME) Cash from Operations (2021 - 2026)
Prime Medicine's (PRME) quarterly Cash from Operations came in at 42710000.0 in Q1 2026, up 12.58% YoY from 37936922.22 in Q1 2025, and down 14.64% on a QoQ basis from 37256000.0 in Q4 2025.
Analysis
Prime Medicine (PRME) Cash from Operations (2021 - 2026) Analysis & Trends
Prime Medicine (PRME) has 6 years of Cash from Operations data on file, last reported at 42710000.0 in Q1 2026.
- Quarterly Cash from Operations rose 12.58% year-over-year to 42710000.0 in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 156417000.0 (down 50.38% YoY) and the FY2025 annual result came in at 162564000.0, down 32.31% from the prior year.
- Cash from Operations declined to 42710000.0 in Q1 2026, from 37256000.0 in the prior quarter.
- In the past five years, Cash from Operations ranged from a high of 16245000.0 in Q4 2024 to a low of 67707000.0 in Q1 2024.
- A 5-year average of 36786941.18 and a median of 40821000.0 in 2023 frame the typical range for Cash from Operations.
- Annual changes were most pronounced in 2024 — Cash from Operations surged 137.03% — and 2025, when it plunged 329.34%.
- Tracing PRME's Cash from Operations over 5 years: stood at 30713000.0 in 2022, then plunged by 42.82% to 43864000.0 in 2023, then surged by 137.03% to 16245000.0 in 2024, then tumbled by 329.34% to 37256000.0 in 2025, then retreated by 14.64% to 42710000.0 in 2026.
- The last three Cash from Operations figures came in at 42710000.0 (Q1 2026), 37256000.0 (Q4 2025), and 35039000.0 (Q3 2025), per Business Quant data.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Cash from Operations (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.47 Bn | 130.62 Bn | 2.84 Bn | 1.13 Bn |
| 2 | Regeneron Pharmaceuticals | 85.18 Bn | 77.19 Bn | 3.93 Bn | 813.00 Mn |
| 3 | Argenx Se | 63.38 Bn | 58.19 Bn | 1.37 Bn | - |
| 4 | Moderna | 58.09 Bn | 52.95 Bn | 52.00 Mn | -526.00 Mn |
| 5 | Revolution Medicines | 44.33 Bn | 44.33 Bn | - | -387.32 Mn |
| 6 | BeOne Medicines | 40.02 Bn | 34.92 Bn | 1.53 Bn | 462.82 Mn |
| 7 | Alnylam Pharmaceuticals | 35.57 Bn | 32.27 Bn | 992.69 Mn | 326.72 Mn |
| 8 | Royalty Pharma | 28.45 Bn | 27.61 Bn | - | 728.46 Mn |
| 9 | Insmed | 27.48 Bn | 26.32 Bn | 358.27 Mn | -88.83 Mn |
| 10 | Prime Medicine | 653.96 Mn | 653.96 Mn | - | -41.05 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -41.05 Mn |
| Mar 31, 2026 | -42.71 Mn |
| Dec 31, 2025 | -37.26 Mn |
| Sep 30, 2025 | -35.04 Mn |
| Jun 30, 2025 | -41.41 Mn |
| Mar 31, 2025 | -48.86 Mn |
| Dec 31, 2024 | 16.25 Mn |
| Sep 30, 2024 | -25.91 Mn |
| Jun 30, 2024 | -45.49 Mn |
| Mar 31, 2024 | -67.71 Mn |
| Dec 31, 2023 | -43.86 Mn |
| Sep 30, 2023 | -39.17 Mn |
| Jun 30, 2023 | -40.82 Mn |
| Mar 31, 2023 | -41.56 Mn |
| Dec 31, 2022 | -30.71 Mn |
| Sep 30, 2022 | -30.10 Mn |
| Jun 30, 2022 | -20.22 Mn |
| Mar 31, 2022 | -50.79 Mn |
| Dec 31, 2021 | -13.19 Mn |