Prime Medicine PRME
NASDAQ PRME
$3.70 -0.01 (-0.27%)
As of: Sep 4, 2026 · 3:59 PM EDT

Prime Medicine (PRME) Cash from Operations (2021 - 2026)

Prime Medicine's (PRME) quarterly Cash from Operations came in at 42710000.0 in Q1 2026, up 12.58% YoY from 37936922.22 in Q1 2025, and down 14.64% on a QoQ basis from 37256000.0 in Q4 2025.

Analysis

Prime Medicine (PRME) Cash from Operations (2021 - 2026) Analysis & Trends

Prime Medicine (PRME) has 6 years of Cash from Operations data on file, last reported at 42710000.0 in Q1 2026.

  • Quarterly Cash from Operations rose 12.58% year-over-year to 42710000.0 in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 156417000.0 (down 50.38% YoY) and the FY2025 annual result came in at 162564000.0, down 32.31% from the prior year.
  • Cash from Operations declined to 42710000.0 in Q1 2026, from 37256000.0 in the prior quarter.
  • In the past five years, Cash from Operations ranged from a high of 16245000.0 in Q4 2024 to a low of 67707000.0 in Q1 2024.
  • A 5-year average of 36786941.18 and a median of 40821000.0 in 2023 frame the typical range for Cash from Operations.
  • Annual changes were most pronounced in 2024 — Cash from Operations surged 137.03% — and 2025, when it plunged 329.34%.
  • Tracing PRME's Cash from Operations over 5 years: stood at 30713000.0 in 2022, then plunged by 42.82% to 43864000.0 in 2023, then surged by 137.03% to 16245000.0 in 2024, then tumbled by 329.34% to 37256000.0 in 2025, then retreated by 14.64% to 42710000.0 in 2026.
  • The last three Cash from Operations figures came in at 42710000.0 (Q1 2026), 37256000.0 (Q4 2025), and 35039000.0 (Q3 2025), per Business Quant data.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cash from Operations (Qtr)
1 Vertex Pharmaceuticals 138.47 Bn 130.62 Bn 2.84 Bn 1.13 Bn
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn 813.00 Mn
3 Argenx Se 63.38 Bn 58.19 Bn 1.37 Bn -
4 Moderna 58.09 Bn 52.95 Bn 52.00 Mn -526.00 Mn
5 Revolution Medicines 44.33 Bn 44.33 Bn - -387.32 Mn
6 BeOne Medicines 40.02 Bn 34.92 Bn 1.53 Bn 462.82 Mn
7 Alnylam Pharmaceuticals 35.57 Bn 32.27 Bn 992.69 Mn 326.72 Mn
8 Royalty Pharma 28.45 Bn 27.61 Bn - 728.46 Mn
9 Insmed 27.48 Bn 26.32 Bn 358.27 Mn -88.83 Mn
10 Prime Medicine 653.96 Mn 653.96 Mn - -41.05 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -41.05 Mn
Mar 31, 2026 -42.71 Mn
Dec 31, 2025 -37.26 Mn
Sep 30, 2025 -35.04 Mn
Jun 30, 2025 -41.41 Mn
Mar 31, 2025 -48.86 Mn
Dec 31, 2024 16.25 Mn
Sep 30, 2024 -25.91 Mn
Jun 30, 2024 -45.49 Mn
Mar 31, 2024 -67.71 Mn
Dec 31, 2023 -43.86 Mn
Sep 30, 2023 -39.17 Mn
Jun 30, 2023 -40.82 Mn
Mar 31, 2023 -41.56 Mn
Dec 31, 2022 -30.71 Mn
Sep 30, 2022 -30.10 Mn
Jun 30, 2022 -20.22 Mn
Mar 31, 2022 -50.79 Mn
Dec 31, 2021 -13.19 Mn