Prime Medicine (PRME) Cash from Operations (2021 - 2026)
Prime Medicine (PRME) posted Cash from Operations of 42710000.0 for Q1 2026, down 14.64% on a QoQ basis from 37256000.0 in Q4 2025, and up 12.58% year-over-year from 37936922.22 in Q1 2025.
Prime Medicine (PRME) Cash from Operations (2021 - 2026) Analysis & Trends
Prime Medicine's Cash from Operations history runs 6 years deep, the most recent figure standing at 42710000.0 for Q1 2026.
- Quarterly Cash from Operations rose 12.58% year-over-year to 42710000.0 in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 156417000.0 (down 50.38% YoY) and the FY2025 annual result came in at 162564000.0, down 32.31% from the prior year.
- Cash from Operations was 42710000.0 for Q1 2026 at Prime Medicine, down from 37256000.0 in the prior quarter.
- Across five years, Cash from Operations topped out at 16245000.0 in Q4 2024 and bottomed at 67707000.0 in Q1 2024.
- A 5-year average of 36786941.18 and a median of 40821000.0 in 2023 frame the typical range for Cash from Operations.
- Annual changes were most pronounced in 2024 — Cash from Operations surged 137.03% — and 2025, when it tumbled 329.34%.
- Prime Medicine's Cash from Operations stood at 30713000.0 in 2022, then slumped by 42.82% to 43864000.0 in 2023, then jumped by 137.03% to 16245000.0 in 2024, then sank by 329.34% to 37256000.0 in 2025, then slipped by 14.64% to 42710000.0 in 2026.
- Business Quant data shows PRME's Cash from Operations at 42710000.0 in Q1 2026, 37256000.0 in Q4 2025, and 35039000.0 in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Cash from Operations (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | -19.59 Mn |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 201.34 Mn |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | -1.53 Mn |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 1.43 Bn |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 1.08 Bn |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | - |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | -354.17 Mn |
| 10 | Prime Medicine | 525.98 Mn | 525.98 Mn | - | -42.71 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -42.71 Mn |
| Mar 31, 2026 | -42.71 Mn |
| Dec 31, 2025 | -37.26 Mn |
| Dec 31, 2025 | -37.26 Mn |
| Sep 30, 2025 | -35.04 Mn |
| Sep 30, 2025 | -35.04 Mn |
| Jun 30, 2025 | -41.41 Mn |
| Jun 30, 2025 | -41.41 Mn |
| Mar 31, 2025 | -48.86 Mn |
| Mar 31, 2025 | -48.86 Mn |
| Dec 31, 2024 | 16.25 Mn |
| Dec 31, 2024 | 16.25 Mn |
| Sep 30, 2024 | -25.91 Mn |
| Sep 30, 2024 | -25.91 Mn |
| Jun 30, 2024 | -45.49 Mn |
| Jun 30, 2024 | -45.49 Mn |
| Mar 31, 2024 | -67.71 Mn |
| Mar 31, 2024 | -67.71 Mn |
| Dec 31, 2023 | -43.86 Mn |
| Dec 31, 2023 | -43.86 Mn |