Prime Medicine (PRME) Retained Earnings (2021 - 2026)

Prime Medicine posted quarterly Retained Earnings of -$1000.0 for Q1 2026, up 100.0% year-on-year from -$500.0 in Q1 2025, and down 101.22% on a QoQ basis from $82000.0 in Q4 2025.

Prime Medicine (PRME) has 6 years of Retained Earnings data on file, last reported at -$1000.0 in Q1 2026.

  • For the quarter ending Q1 2026, Retained Earnings rose 100.0% year-over-year to -$1000.0; the trailing twelve-month figure through Mar 2026 stood at -$1000.0 (up 100.0% YoY), and the FY2025 full-year result was $82000.0, up 8100.0% from the prior year.
  • Retained Earnings for Q1 2026 stood at -$1000.0, down from $82000.0 in the prior quarter.
  • Across five years, Retained Earnings topped out at $82000.0 in Q4 2025 and bottomed at -$842.3 million in Q3 2025.
  • The 5-year median for Retained Earnings is -$253.9 million (2022), against an average of -$312.6 million.
  • Peak annual rise in Retained Earnings reached 8100.0% in 2025, while the deepest fall reached 777900.0% in 2025.
  • A 5-year view of Retained Earnings shows it stood at -$384000.0 in 2022, then tumbled by 127850.52% to -$491.3 million in 2023, then jumped by 100.0% to $1000.0 in 2024, then surged by 8100.0% to $82000.0 in 2025, then slumped by 101.22% to -$1000.0 in 2026.
  • The last three Retained Earnings figures came in at -$1000.0 (Q1 2026), $82000.0 (Q4 2025), and -$842.3 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Retained Earnings (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -211.85 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -153.89 Mn
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 1.00 Bn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -438.66 Mn
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -279.00 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 14.59 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - 130.89 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 36.42 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn -24.89 Mn
10 Prime Medicine 601.24 Mn 601.24 Mn - -1,000.00

Historic Data

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DateValue
Mar 31, 2026 -1,000.00
Dec 31, 2025 82,000.00
Sep 30, 2025 -842.30 Mn
Jun 30, 2025 -791.70 Mn
Mar 31, 2025 -739.10 Mn
Dec 31, 2024 1,000.00
Sep 30, 2024 -644.94 Mn
Jun 30, 2024 -592.42 Mn
Mar 31, 2024 -95,000.00
Dec 31, 2023 -491.33 Mn
Sep 30, 2023 -149,000.00
Jun 30, 2023 -268,000.00
Mar 31, 2023 -332.60 Mn
Dec 31, 2022 -384,000.00
Sep 30, 2022 -253.91 Mn
Dec 31, 2021 -171.38 Mn