Prime Medicine (PRME) Share-based Compensation (2021 - 2026)

Prime Medicine posted quarterly Share-based Compensation of $4.6 million for Q1 2026, down 18.25% year-on-year from $5.7 million in Q1 2025, and up 2.86% on a QoQ basis from $4.5 million in Q4 2025.

Prime Medicine (PRME) has 6 years of Share-based Compensation data on file, last reported at $4.6 million in Q1 2026.

  • For the quarter ending Q1 2026, Share-based Compensation fell 18.25% year-over-year to $4.6 million; the trailing twelve-month figure through Mar 2026 stood at $28.2 million (up 6.37% YoY), and the FY2025 full-year result was $29.3 million, up 12.28% from the prior year.
  • Share-based Compensation for Q1 2026 stood at $4.6 million, up from $4.5 million in the prior quarter.
  • Across five years, Share-based Compensation topped out at $12.7 million in Q3 2025 and bottomed at $1.1 million in Q1 2022.
  • The 5-year median for Share-based Compensation is $4.5 million (2025), against an average of $4.7 million.
  • The widest annual swing landed in 2024, when Share-based Compensation surged 209.88%; it then declined 24.0% in 2025.
  • A 5-year view of Share-based Compensation shows it stood at $2.6 million in 2022, then jumped by 72.07% to $4.4 million in 2023, then soared by 34.14% to $5.9 million in 2024, then declined by 24.0% to $4.5 million in 2025, then increased by 2.86% to $4.6 million in 2026.
  • The last three Share-based Compensation figures came in at $4.6 million (Q1 2026), $4.5 million (Q4 2025), and $12.7 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Share-based Compensation (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - 892,057.00
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - 305,000.00
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 166.40 Mn
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 257.40 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 70.15 Mn
10 Prime Medicine 601.24 Mn 601.24 Mn - 4.64 Mn

Historic Data

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DateValue
Mar 31, 2026 4.64 Mn
Mar 31, 2026 4.64 Mn
Dec 31, 2025 4.52 Mn
Dec 31, 2025 4.52 Mn
Sep 30, 2025 12.75 Mn
Sep 30, 2025 12.75 Mn
Jun 30, 2025 6.33 Mn
Jun 30, 2025 6.33 Mn
Mar 31, 2025 5.68 Mn
Mar 31, 2025 5.68 Mn
Dec 31, 2024 5.94 Mn
Dec 31, 2024 5.94 Mn
Sep 30, 2024 6.83 Mn
Sep 30, 2024 6.83 Mn
Jun 30, 2024 8.09 Mn
Jun 30, 2024 8.09 Mn
Mar 31, 2024 5.21 Mn
Mar 31, 2024 5.21 Mn
Dec 31, 2023 4.43 Mn
Dec 31, 2023 4.43 Mn
Sep 30, 2023 4.22 Mn
Sep 30, 2023 4.22 Mn
Jun 30, 2023 3.58 Mn
Jun 30, 2023 3.58 Mn
Mar 31, 2023 1.68 Mn
Mar 31, 2023 1.68 Mn
Dec 31, 2022 2.57 Mn
Dec 31, 2022 2.57 Mn
Sep 30, 2022 1.42 Mn
Sep 30, 2022 1.42 Mn
Jun 30, 2022 1.35 Mn
Jun 30, 2022 1.35 Mn
Mar 31, 2022 1.12 Mn
Mar 31, 2022 1.12 Mn
Dec 31, 2021 1.11 Mn
Dec 31, 2021 1.11 Mn