Prime Medicine (PRME) Share-based Compensation (2021 - 2026)

Prime Medicine (PRME) posted Share-based Compensation of $4.6 million for Q1 2026, up 108.52% on a QoQ basis from -$54.5 million in Q4 2025, and down 18.25% year-over-year from $5.7 million in Q1 2025.

Prime Medicine (PRME) Share-based Compensation (2021 - 2026) Analysis & Trends

Prime Medicine's Share-based Compensation history runs 6 years deep, the most recent figure standing at $4.6 million for Q1 2026.

  • Quarterly Share-based Compensation fell 18.25% year-over-year to $4.6 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $28.2 million (up 396.94% YoY) and the FY2025 annual result came in at $29.3 million, down 34.87% from the prior year.
  • Share-based Compensation was $4.6 million for Q1 2026 at Prime Medicine, up from -$54.5 million in the prior quarter.
  • Across five years, Share-based Compensation topped out at $78.1 million in Q2 2025 and bottomed at -$54.5 million in Q4 2025.
  • A 5-year average of $7.9 million and a median of $5.0 million in 2023 frame the typical range for Share-based Compensation.
  • Peak annual rise in Share-based Compensation reached 650.18% in 2024, while the deepest fall reached 700.97% in 2024.
  • Prime Medicine's Share-based Compensation stood at $24.7 million in 2022, then plunged by 125.16% to -$6.2 million in 2023, then jumped by 608.93% to $31.6 million in 2024, then tumbled by 272.24% to -$54.5 million in 2025, then jumped by 108.52% to $4.6 million in 2026.
  • Business Quant data shows PRME's Share-based Compensation at $4.6 million in Q1 2026, -$54.5 million in Q4 2025, and $78.1 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Share-based Compensation (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - 6.39 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 9.26 Mn
4 NuCana 279.75 Bn 279.75 Bn - 1.18 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 166.40 Mn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 257.40 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - 87.30 Mn
10 Prime Medicine 525.98 Mn 525.98 Mn - 4.64 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 4.64 Mn
Mar 31, 2026 4.64 Mn
Dec 31, 2025 -54.49 Mn
Dec 31, 2025 -54.49 Mn
Jun 30, 2025 78.08 Mn
Jun 30, 2025 78.08 Mn
Mar 31, 2025 5.68 Mn
Mar 31, 2025 5.68 Mn
Sep 30, 2024 31.64 Mn
Sep 30, 2024 31.64 Mn
Jun 30, 2024 -31.64 Mn
Jun 30, 2024 -31.64 Mn
Mar 31, 2024 44.94 Mn
Mar 31, 2024 44.94 Mn
Dec 31, 2023 -6.22 Mn
Dec 31, 2023 -6.22 Mn
Sep 30, 2023 4.22 Mn
Sep 30, 2023 4.22 Mn
Jun 30, 2023 5.26 Mn
Jun 30, 2023 5.26 Mn