Prime Medicine (PRME) Operating Leases (2021 - 2026)

Prime Medicine (PRME) posted Operating Leases of $114.5 million for Q1 2026, up 5.75% on a QoQ basis from $108.3 million in Q4 2025, and up 1982.04% year-over-year from $5.5 million in Q1 2025.

Prime Medicine (PRME) Operating Leases (2021 - 2026) Analysis & Trends

Prime Medicine's Operating Leases history runs 6 years deep, the most recent figure standing at $114.5 million for Q1 2026.

  • Quarterly Operating Leases rose 1982.04% year-over-year to $114.5 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $114.5 million (up 1982.04% YoY) and the FY2025 annual result came in at $108.3 million, up 191.26% from the prior year.
  • Operating Leases was $114.5 million for Q1 2026 at Prime Medicine, up from $108.3 million in the prior quarter.
  • Across five years, Operating Leases topped out at $118.1 million in Q3 2025 and bottomed at $4.4 million in Q4 2023.
  • A 5-year average of $47.5 million and a median of $33.6 million in 2024 frame the typical range for Operating Leases.
  • Annual changes were most pronounced in 2025 — Operating Leases sank 83.63% — and 2026, when it soared 1982.04%.
  • Prime Medicine's Operating Leases stood at $17.1 million in 2022, then tumbled by 74.45% to $4.4 million in 2023, then jumped by 753.34% to $37.2 million in 2024, then jumped by 191.26% to $108.3 million in 2025, then advanced by 5.75% to $114.5 million in 2026.
  • Business Quant data shows PRME's Operating Leases at $114.5 million in Q1 2026, $108.3 million in Q4 2025, and $118.1 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn
4 NuCana 279.75 Bn 279.75 Bn -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn
7 Belite Bio 62.51 Bn 62.51 Bn -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn
9 Revolution Medicines 37.78 Bn 37.78 Bn -
10 Prime Medicine 525.98 Mn 525.98 Mn -

Historic Data

Download Data
DateValue
Mar 31, 2026 114.51 Mn
Dec 31, 2025 108.29 Mn
Sep 30, 2025 118.14 Mn
Jun 30, 2025 112.48 Mn
Mar 31, 2025 5.50 Mn
Dec 31, 2024 37.18 Mn
Sep 30, 2024 41.25 Mn
Jun 30, 2024 33.60 Mn
Mar 31, 2024 33.60 Mn
Dec 31, 2023 4.36 Mn
Sep 30, 2023 17.04 Mn
Jun 30, 2023 11.93 Mn
Mar 31, 2023 25.96 Mn
Dec 31, 2022 17.05 Mn
Sep 30, 2022 31.44 Mn
Dec 31, 2021 3.07 Mn