Prime Medicine (PRME) Operating Leases (2021 - 2026)

Prime Medicine's (PRME) quarterly Operating Leases came in at $114.5 million in Q1 2026, up 1982.04% YoY from $5.5 million in Q1 2025, and up 5.75% on a QoQ basis from $108.3 million in Q4 2025.

Prime Medicine (PRME) Operating Leases (2021 - 2026) Analysis & Trends

Prime Medicine (PRME) has 6 years of Operating Leases data on file, last reported at $114.5 million in Q1 2026.

  • Quarterly Operating Leases rose 1982.04% year-over-year to $114.5 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $114.5 million (up 1982.04% YoY) and the FY2025 annual result came in at $108.3 million, up 191.26% from the prior year.
  • Operating Leases improved to $114.5 million in Q1 2026, from $108.3 million in the prior quarter.
  • In the past five years, Operating Leases ranged from a high of $118.1 million in Q3 2025 to a low of $4.4 million in Q4 2023.
  • A 5-year average of $47.5 million and a median of $33.6 million in 2024 frame the typical range for Operating Leases.
  • Annual changes were most pronounced in 2025 — Operating Leases slumped 83.63% — and 2026, when it soared 1982.04%.
  • Tracing PRME's Operating Leases over 5 years: stood at $17.1 million in 2022, then sank by 74.45% to $4.4 million in 2023, then surged by 753.34% to $37.2 million in 2024, then surged by 191.26% to $108.3 million in 2025, then rose by 5.75% to $114.5 million in 2026.
  • The last three Operating Leases figures came in at $114.5 million (Q1 2026), $108.3 million (Q4 2025), and $118.1 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn
4 Revolution Medicines 43.64 Bn 43.64 Bn -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn
7 Royalty Pharma 33.72 Bn 35.84 Bn -
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn
10 Prime Medicine 558.48 Mn 558.48 Mn -

Historic Data

Download Data
DateValue
Jun 30, 2026 112.48 Mn
Mar 31, 2026 114.51 Mn
Dec 31, 2025 108.29 Mn
Sep 30, 2025 118.14 Mn
Jun 30, 2025 112.48 Mn
Mar 31, 2025 5.50 Mn
Dec 31, 2024 37.18 Mn
Sep 30, 2024 41.25 Mn
Jun 30, 2024 33.60 Mn
Mar 31, 2024 33.60 Mn
Dec 31, 2023 4.36 Mn
Sep 30, 2023 17.04 Mn
Jun 30, 2023 11.93 Mn
Mar 31, 2023 25.96 Mn
Dec 31, 2022 17.05 Mn
Sep 30, 2022 31.44 Mn
Dec 31, 2021 3.07 Mn