Prime Medicine (PRME) Operating Leases (2021 - 2026)

Prime Medicine posted quarterly Operating Leases of $114.5 million for Q1 2026, up 45.69% year-on-year from $78.6 million in Q1 2025, and up 5.75% on a QoQ basis from $108.3 million in Q4 2025.

Prime Medicine (PRME) has 6 years of Operating Leases data on file, last reported at $114.5 million in Q1 2026.

  • For the quarter ending Q1 2026, Operating Leases rose 45.69% year-over-year to $114.5 million; the trailing twelve-month figure through Mar 2026 stood at $114.5 million (up 45.69% YoY), and the FY2025 full-year result was $108.3 million, up 191.26% from the prior year.
  • Operating Leases for Q1 2026 stood at $114.5 million, up from $108.3 million in the prior quarter.
  • Across five years, Operating Leases topped out at $114.5 million in Q1 2026 and bottomed at $4.4 million in Q4 2023.
  • The 5-year median for Operating Leases is $33.6 million (2024), against an average of $50.8 million.
  • The widest annual swing landed in 2023, when Operating Leases slumped 74.45%; it then surged 753.34% in 2024.
  • A 5-year view of Operating Leases shows it stood at $17.1 million in 2022, then plunged by 74.45% to $4.4 million in 2023, then soared by 753.34% to $37.2 million in 2024, then soared by 191.26% to $108.3 million in 2025, then gained by 5.75% to $114.5 million in 2026.
  • The last three Operating Leases figures came in at $114.5 million (Q1 2026), $108.3 million (Q4 2025), and $110.4 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn -
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn -
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn
7 Evaxion A 62.56 Bn 62.54 Bn -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn
10 Prime Medicine 601.24 Mn 601.24 Mn -

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 114.51 Mn
Dec 31, 2025 108.29 Mn
Sep 30, 2025 110.42 Mn
Jun 30, 2025 112.48 Mn
Mar 31, 2025 78.60 Mn
Dec 31, 2024 37.18 Mn
Sep 30, 2024 36.76 Mn
Jun 30, 2024 33.60 Mn
Mar 31, 2024 33.60 Mn
Dec 31, 2023 4.36 Mn
Sep 30, 2023 17.04 Mn
Jun 30, 2023 11.93 Mn
Mar 31, 2023 25.96 Mn
Dec 31, 2022 17.05 Mn
Sep 30, 2022 19.86 Mn
Dec 31, 2021 3.07 Mn