Prime Medicine (PRME) Consolidated Net Income (2021 - 2026)

Prime Medicine posted quarterly Consolidated Net Income of -$49.6 million for Q1 2026, up 4.35% year-on-year from -$47.6 million in Q1 2025, and down 4.44% on a QoQ basis from -$47.5 million in Q4 2025.

Prime Medicine (PRME) has 6 years of Consolidated Net Income data on file, last reported at -$49.6 million in Q1 2026.

  • For the quarter ending Q1 2026, Consolidated Net Income rose 4.35% year-over-year to -$49.6 million; the trailing twelve-month figure through Mar 2026 stood at -$202.6 million (changed 0.28% YoY), and the FY2025 full-year result was -$204.2 million, down 4.25% from the prior year.
  • Consolidated Net Income for Q1 2026 stood at -$49.6 million, down from -$47.5 million in the prior quarter.
  • Across five years, Consolidated Net Income topped out at -$23.8 million in Q1 2022 and bottomed at -$65.6 million in Q4 2023.
  • The 5-year median for Consolidated Net Income is -$47.5 million (2025), against an average of -$45.3 million.
  • Peak annual rise in Consolidated Net Income reached 37.54% in 2022, while the deepest fall reached 78.83% in 2022.
  • A 5-year view of Consolidated Net Income shows it stood at -$39.3 million in 2022, then sank by 67.1% to -$65.6 million in 2023, then jumped by 35.6% to -$42.3 million in 2024, then dropped by 12.42% to -$47.5 million in 2025, then retreated by 4.44% to -$49.6 million in 2026.
  • The last three Consolidated Net Income figures came in at -$49.6 million (Q1 2026), -$47.5 million (Q4 2025), and -$52.8 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Consol Net Inc. (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -2.99 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -8.40 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -14.46 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.03 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.40 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 727.20 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 205.99 Mn
10 Prime Medicine 601.24 Mn 601.24 Mn - -49.63 Mn

Historic Data

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DateValue
Mar 31, 2026 -49.63 Mn
Dec 31, 2025 -47.53 Mn
Sep 30, 2025 -52.83 Mn
Jun 30, 2025 -52.59 Mn
Mar 31, 2025 -51.89 Mn
Dec 31, 2024 -42.28 Mn
Sep 30, 2024 -52.52 Mn
Jun 30, 2024 -55.33 Mn
Mar 31, 2024 -45.76 Mn
Dec 31, 2023 -65.64 Mn
Sep 30, 2023 -50.71 Mn
Jun 30, 2023 -42.39 Mn
Mar 31, 2023 -39.40 Mn
Dec 31, 2022 -39.28 Mn
Sep 30, 2022 -29.35 Mn
Jun 30, 2022 -29.35 Mn
Mar 31, 2022 -23.84 Mn
Dec 31, 2021 -62.90 Mn
Sep 30, 2021 -16.41 Mn