Prime Medicine PRME
NASDAQ PRME
$3.70 -0.01 (-0.27%)
As of: Sep 4, 2026 · 3:59 PM EDT

Prime Medicine (PRME) Consolidated Net Income (2021 - 2026)

Prime Medicine's (PRME) quarterly Consolidated Net Income came in at -$228.7 million in Q1 2026, down 340.77% YoY from $95.0 million in Q1 2025, and down 381.22% on a QoQ basis from -$47.5 million in Q4 2025.

Analysis

Prime Medicine (PRME) Consolidated Net Income (2021 - 2026) Analysis & Trends

Prime Medicine (PRME) has 6 years of Consolidated Net Income data on file, last reported at -$228.7 million in Q1 2026.

  • Quarterly Consolidated Net Income fell 340.77% year-over-year to -$228.7 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$453.2 million (down 124.36% YoY) and the FY2025 annual result came in at -$204.2 million, down 4.25% from the prior year.
  • Consolidated Net Income eased to -$228.7 million in Q1 2026, from -$47.5 million in the prior quarter.
  • In the past five years, Consolidated Net Income ranged from a high of -$23.8 million in Q1 2022 to a low of -$228.7 million in Q1 2026.
  • A 5-year average of -$60.1 million and a median of -$47.5 million in 2025 frame the typical range for Consolidated Net Income.
  • Annual changes were most pronounced in 2022 — Consolidated Net Income jumped 37.56% — and 2026, when it tumbled 340.77%.
  • Tracing PRME's Consolidated Net Income over 5 years: stood at -$39.3 million in 2022, then slumped by 67.1% to -$65.6 million in 2023, then soared by 35.6% to -$42.3 million in 2024, then dropped by 12.42% to -$47.5 million in 2025, then slumped by 381.22% to -$228.7 million in 2026.
  • The last three Consolidated Net Income figures came in at -$228.7 million (Q1 2026), -$47.5 million (Q4 2025), and -$124.4 million (Q3 2025), per Business Quant data.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Consol Net Inc. (Qtr)
1 Vertex Pharmaceuticals 138.47 Bn 130.62 Bn 2.84 Bn 1.10 Bn
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn 1.30 Bn
3 Argenx Se 63.38 Bn 58.19 Bn 1.37 Bn 601.00 Mn
4 Moderna 58.09 Bn 52.95 Bn 52.00 Mn -782.00 Mn
5 Revolution Medicines 44.33 Bn 44.33 Bn - -644.37 Mn
6 BeOne Medicines 40.02 Bn 34.92 Bn 1.53 Bn 237.01 Mn
7 Alnylam Pharmaceuticals 35.57 Bn 32.27 Bn 992.69 Mn 164.49 Mn
8 Royalty Pharma 28.45 Bn 27.61 Bn - 81.49 Mn
9 Insmed 27.48 Bn 26.32 Bn 358.27 Mn -13.27 Mn
10 Prime Medicine 653.96 Mn 653.96 Mn - -42.50 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -42.50 Mn
Mar 31, 2026 -49.63 Mn
Dec 31, 2025 -47.53 Mn
Sep 30, 2025 -52.83 Mn
Jun 30, 2025 -52.59 Mn
Mar 31, 2025 -51.89 Mn
Dec 31, 2024 -42.28 Mn
Sep 30, 2024 -52.52 Mn
Jun 30, 2024 -55.33 Mn
Mar 31, 2024 -45.76 Mn
Dec 31, 2023 -65.64 Mn
Sep 30, 2023 -50.71 Mn
Jun 30, 2023 -42.39 Mn
Mar 31, 2023 -39.40 Mn
Dec 31, 2022 -39.28 Mn
Sep 30, 2022 -29.35 Mn
Jun 30, 2022 -29.35 Mn
Mar 31, 2022 -23.84 Mn
Dec 31, 2021 -62.90 Mn
Sep 30, 2021 -16.41 Mn