Prime Medicine (PRME) Cash from Investing Activities (2021 - 2026)
Prime Medicine's (PRME) quarterly Cash from Investing Activities came in at $43.4 million in Q1 2026, up 190.89% YoY from $14.9 million in Q1 2025, and up 53.16% on a QoQ basis from $28.3 million in Q4 2025.
Analysis
Prime Medicine (PRME) Cash from Investing Activities (2021 - 2026) Analysis & Trends
Prime Medicine (PRME) has 6 years of Cash from Investing Activities data on file, last reported at $43.4 million in Q1 2026.
- Quarterly Cash from Investing Activities rose 190.89% year-over-year to $43.4 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$17.6 million (down 130.53% YoY) and the FY2025 annual result came in at -$108.8 million, down 258.88% from the prior year.
- Cash from Investing Activities improved to $43.4 million in Q1 2026, from $28.3 million in the prior quarter.
- In the past five years, Cash from Investing Activities ranged from a high of $50.3 million in Q3 2024 to a low of -$92.1 million in Q3 2025.
- A 5-year average of -$1.5 million and a median of $2.8 million in 2025 frame the typical range for Cash from Investing Activities.
- Annual changes were most pronounced in 2023 — Cash from Investing Activities jumped 401.64% — and 2025, when it sank 282.99%.
- Tracing PRME's Cash from Investing Activities over 5 years: stood at -$13.7 million in 2022, then jumped by 401.64% to $41.3 million in 2023, then grew by 16.88% to $48.3 million in 2024, then slumped by 41.29% to $28.3 million in 2025, then jumped by 53.16% to $43.4 million in 2026.
- The last three Cash from Investing Activities figures came in at $43.4 million (Q1 2026), $28.3 million (Q4 2025), and -$92.1 million (Q3 2025), per Business Quant data.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Cash from Investing Activities (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.47 Bn | 130.62 Bn | 2.84 Bn | -45.80 Mn |
| 2 | Regeneron Pharmaceuticals | 85.18 Bn | 77.19 Bn | 3.93 Bn | -92.70 Mn |
| 3 | Argenx Se | 63.38 Bn | 58.19 Bn | 1.37 Bn | - |
| 4 | Moderna | 58.09 Bn | 52.95 Bn | 52.00 Mn | 329.00 Mn |
| 5 | Revolution Medicines | 44.33 Bn | 44.33 Bn | - | -1.66 Bn |
| 6 | BeOne Medicines | 40.02 Bn | 34.92 Bn | 1.53 Bn | -49.35 Mn |
| 7 | Alnylam Pharmaceuticals | 35.57 Bn | 32.27 Bn | 992.69 Mn | -363.46 Mn |
| 8 | Royalty Pharma | 28.45 Bn | 27.61 Bn | - | -229.72 Mn |
| 9 | Insmed | 27.48 Bn | 26.32 Bn | 358.27 Mn | 24.51 Mn |
| 10 | Prime Medicine | 653.96 Mn | 653.96 Mn | - | 24.03 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 24.03 Mn |
| Mar 31, 2026 | 43.39 Mn |
| Dec 31, 2025 | 28.33 Mn |
| Sep 30, 2025 | -92.12 Mn |
| Jun 30, 2025 | 2.77 Mn |
| Mar 31, 2025 | -47.74 Mn |
| Dec 31, 2024 | 48.25 Mn |
| Sep 30, 2024 | 50.34 Mn |
| Jun 30, 2024 | 6.89 Mn |
| Mar 31, 2024 | -37.03 Mn |
| Dec 31, 2023 | 41.29 Mn |
| Sep 30, 2023 | -37.77 Mn |
| Jun 30, 2023 | 27.86 Mn |
| Mar 31, 2023 | -12.67 Mn |
| Dec 31, 2022 | -13.69 Mn |
| Sep 30, 2022 | -13.51 Mn |
| Jun 30, 2022 | -50.79 Mn |
| Mar 31, 2022 | 30.89 Mn |
| Dec 31, 2021 | 12.15 Mn |