Prime Medicine (PRME) Cash from Investing Activities (2021 - 2026)

Prime Medicine posted quarterly Cash from Investing Activities of $43.4 million for Q1 2026, up 190.89% year-on-year from $14.9 million in Q1 2025, and up 53.16% on a QoQ basis from $28.3 million in Q4 2025.

Prime Medicine (PRME) has 6 years of Cash from Investing Activities data on file, last reported at $43.4 million in Q1 2026.

  • For the quarter ending Q1 2026, Cash from Investing Activities rose 190.89% year-over-year to $43.4 million; the trailing twelve-month figure through Mar 2026 stood at -$17.6 million (down 130.53% YoY), and the FY2025 full-year result was -$108.8 million, down 258.88% from the prior year.
  • Cash from Investing Activities for Q1 2026 stood at $43.4 million, up from $28.3 million in the prior quarter.
  • Across five years, Cash from Investing Activities topped out at $50.3 million in Q3 2024 and bottomed at -$92.1 million in Q3 2025.
  • The 5-year median for Cash from Investing Activities is $2.8 million (2025), against an average of -$1.5 million.
  • The widest annual swing landed in 2023, when Cash from Investing Activities jumped 401.64%; it then tumbled 282.99% in 2025.
  • A 5-year view of Cash from Investing Activities shows it stood at -$13.7 million in 2022, then surged by 401.64% to $41.3 million in 2023, then increased by 16.88% to $48.3 million in 2024, then sank by 41.29% to $28.3 million in 2025, then surged by 53.16% to $43.4 million in 2026.
  • The last three Cash from Investing Activities figures came in at $43.4 million (Q1 2026), $28.3 million (Q4 2025), and -$92.1 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cash from Investing Activities (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -2.89 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 638.50 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn -431.90 Mn
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn -428.90 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn -25.54 Mn
10 Prime Medicine 601.24 Mn 601.24 Mn - 43.39 Mn

Historic Data

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DateValue
Mar 31, 2026 43.39 Mn
Mar 31, 2026 43.39 Mn
Dec 31, 2025 28.33 Mn
Dec 31, 2025 28.33 Mn
Sep 30, 2025 -92.12 Mn
Sep 30, 2025 -92.12 Mn
Jun 30, 2025 2.77 Mn
Jun 30, 2025 2.77 Mn
Mar 31, 2025 -47.74 Mn
Mar 31, 2025 -47.74 Mn
Dec 31, 2024 48.25 Mn
Dec 31, 2024 48.25 Mn
Sep 30, 2024 50.34 Mn
Sep 30, 2024 50.34 Mn
Jun 30, 2024 6.89 Mn
Jun 30, 2024 6.89 Mn
Mar 31, 2024 -37.03 Mn
Mar 31, 2024 -37.03 Mn
Dec 31, 2023 41.29 Mn
Dec 31, 2023 41.29 Mn
Sep 30, 2023 -37.77 Mn
Sep 30, 2023 -37.77 Mn
Jun 30, 2023 27.86 Mn
Jun 30, 2023 27.86 Mn
Mar 31, 2023 -12.67 Mn
Mar 31, 2023 -12.67 Mn
Dec 31, 2022 -13.69 Mn
Dec 31, 2022 -13.69 Mn
Sep 30, 2022 -13.51 Mn
Sep 30, 2022 -13.51 Mn
Jun 30, 2022 -50.79 Mn
Jun 30, 2022 -50.79 Mn
Mar 31, 2022 30.89 Mn
Mar 31, 2022 30.89 Mn
Dec 31, 2021 12.15 Mn
Dec 31, 2021 12.15 Mn