Prime Medicine (PRME) Cash from Investing Activities (2021 - 2026)

Prime Medicine (PRME) posted Cash from Investing Activities of $43.4 million for Q1 2026, up 53.16% on a QoQ basis from $28.3 million in Q4 2025, and up 190.89% year-over-year from $14.9 million in Q1 2025.

Prime Medicine (PRME) Cash from Investing Activities (2021 - 2026) Analysis & Trends

Prime Medicine's Cash from Investing Activities history runs 6 years deep, the most recent figure standing at $43.4 million for Q1 2026.

  • Quarterly Cash from Investing Activities rose 190.89% year-over-year to $43.4 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$17.6 million (down 130.53% YoY) and the FY2025 annual result came in at -$108.8 million, down 258.88% from the prior year.
  • Cash from Investing Activities was $43.4 million for Q1 2026 at Prime Medicine, up from $28.3 million in the prior quarter.
  • Across five years, Cash from Investing Activities topped out at $50.3 million in Q3 2024 and bottomed at -$92.1 million in Q3 2025.
  • A 5-year average of -$1.5 million and a median of $2.8 million in 2025 frame the typical range for Cash from Investing Activities.
  • Annual changes were most pronounced in 2023 — Cash from Investing Activities jumped 401.64% — and 2025, when it plunged 282.99%.
  • Prime Medicine's Cash from Investing Activities stood at -$13.7 million in 2022, then soared by 401.64% to $41.3 million in 2023, then rose by 16.88% to $48.3 million in 2024, then plunged by 41.29% to $28.3 million in 2025, then soared by 53.16% to $43.4 million in 2026.
  • Business Quant data shows PRME's Cash from Investing Activities at $43.4 million in Q1 2026, $28.3 million in Q4 2025, and -$92.1 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cash from Investing Activities (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn -45.51 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn -431.90 Mn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn -428.90 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -
9 Revolution Medicines 37.37 Bn 37.37 Bn - 172.62 Mn
10 Prime Medicine 524.20 Mn 524.20 Mn - 43.39 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 43.39 Mn
Mar 31, 2026 43.39 Mn
Dec 31, 2025 28.33 Mn
Dec 31, 2025 28.33 Mn
Sep 30, 2025 -92.12 Mn
Sep 30, 2025 -92.12 Mn
Jun 30, 2025 2.77 Mn
Jun 30, 2025 2.77 Mn
Mar 31, 2025 -47.74 Mn
Mar 31, 2025 -47.74 Mn
Dec 31, 2024 48.25 Mn
Dec 31, 2024 48.25 Mn
Sep 30, 2024 50.34 Mn
Sep 30, 2024 50.34 Mn
Jun 30, 2024 6.89 Mn
Jun 30, 2024 6.89 Mn
Mar 31, 2024 -37.03 Mn
Mar 31, 2024 -37.03 Mn
Dec 31, 2023 41.29 Mn
Dec 31, 2023 41.29 Mn