Prime Medicine (PRME) FCF Margin (2024 - 2026)
Prime Medicine's (PRME) quarterly FCF Margin came in at 4989.49% in Q1 2026, down 146273.0% YoY from N/an in Q1 2025, and down 11.36% on a QoQ basis from 4480.43% in Q4 2025.
Prime Medicine (PRME) FCF Margin (2024 - 2026) Analysis & Trends
Prime Medicine (PRME) has 3 years of FCF Margin data on file, last reported at 4989.49% in Q1 2026.
- Quarterly FCF Margin fell 146273.0% year-over-year to 4989.49% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 3929.75% (down 115393.0% YoY) and the FY2025 annual result came in at 3607.41%, up 55012.0% from the prior year.
- FCF Margin slipped to 4989.49% in Q1 2026, from 4480.43% in the prior quarter.
- In the past five years, FCF Margin ranged from a high of 696.38% in Q4 2024 to a low of 11597.29% in Q1 2024.
- A 3-year average of 5128.92% and a median of 4003.59% in 2025 frame the typical range for FCF Margin.
- The widest YoY moves for FCF Margin: up 807054 bps in 2025, down 517681 bps in 2025.
- Tracing PRME's FCF Margin over 3 years: stood at 696.38% in 2024, then tumbled by 743 bps to 4480.43% in 2025, then dropped by 11 bps to 4989.49% in 2026.
- The last three FCF Margin figures came in at 4989.49% (Q1 2026), 4480.43% (Q4 2025), and 3194.45% (Q3 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | FCF Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 30.39% |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 13.35% |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | - |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | - |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 25.68% |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | -77,594.17% |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 70.82% |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | 22.62% |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | -22.35% |
| 10 | Prime Medicine | 558.48 Mn | 558.48 Mn | - | -3,560.83% |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | -3,560.83% |
| Mar 31, 2026 | -4,989.49% |
| Dec 31, 2025 | -4,480.43% |
| Sep 30, 2025 | -3,194.45% |
| Jun 30, 2025 | -3,510.13% |
| Mar 31, 2025 | -3,526.75% |
| Dec 31, 2024 | 696.38% |
| Sep 30, 2024 | -10,429.19% |
| Mar 31, 2024 | -11,597.29% |