Prime Medicine (PRME) FCF Margin (2024 - 2026)
Prime Medicine (PRME) reported FCF Margin of 5014.49% for Q1 2026, down 148773.0% on a YoY basis from N/an in Q1 2025, and down 26.84% quarter-over-quarter from 3953.34% in Q4 2025.
Prime Medicine (PRME) FCF Margin (2024 - 2026) Analysis & Trends
Prime Medicine has reported FCF Margin for 3 years, with the latest figure at 5014.49% in Q1 2026.
- For the quarter ending Q1 2026, FCF Margin fell 148773.0% year-over-year to 5014.49%; the trailing twelve-month figure through Mar 2026 stood at 3825.56% (down 108851.0% YoY), and the FY2025 full-year result was 3512.05%, up 64548.0% from the prior year.
- FCF Margin for Q1 2026 stood at 5014.49%, down from 3953.34% in the prior quarter.
- The five-year high for FCF Margin was 696.38% in Q4 2024, with the low at 12281.34% in Q3 2024.
- Historically, FCF Margin has averaged 5329.21% across 3 years, with a median of 3740.05% in 2025.
- The largest YoY upside for FCF Margin was 908689 bps in 2025 against a maximum downside of 464972 bps in 2025.
- Prime Medicine's FCF Margin stood at 696.38% in 2024, then tumbled by 668 bps to 3953.34% in 2025, then slipped by 27 bps to 5014.49% in 2026.
- The last three FCF Margin figures came in at 5014.49% (Q1 2026), 3953.34% (Q4 2025), and 3194.45% (Q3 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | FCF Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -3.98% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 43.35% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Prime Medicine | 572.02 Mn | 572.02 Mn | - | -5,014.49% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -5,014.49% |
| Dec 31, 2025 | -3,953.34% |
| Sep 30, 2025 | -3,194.45% |
| Jun 30, 2025 | -3,510.13% |
| Mar 31, 2025 | -3,526.75% |
| Dec 31, 2024 | 696.38% |
| Sep 30, 2024 | -12,281.34% |
| Mar 31, 2024 | -11,849.58% |