Prime Medicine (PRME) FCF Margin (2024 - 2026)
Prime Medicine posted quarterly FCF Margin of 5014.49% for Q1 2026, down 148773.0% year-on-year from N/an in Q1 2025, and down 26.84% on a QoQ basis from 3953.34% in Q4 2025.
Prime Medicine (PRME) has 3 years of FCF Margin data on file, last reported at 5014.49% in Q1 2026.
- For the quarter ending Q1 2026, FCF Margin fell 148773.0% year-over-year to 5014.49%; the trailing twelve-month figure through Mar 2026 stood at 3825.56% (down 108851.0% YoY), and the FY2025 full-year result was 3512.05%, up 64548.0% from the prior year.
- FCF Margin for Q1 2026 stood at 5014.49%, down from 3953.34% in the prior quarter.
- Across five years, FCF Margin topped out at 696.38% in Q4 2024 and bottomed at 12281.34% in Q3 2024.
- The 3-year median for FCF Margin is 3740.05% (2025), against an average of 5329.21%.
- Peak annual rise in FCF Margin reached 908689 bps in 2025, while the deepest fall reached 464972 bps in 2025.
- A 3-year view of FCF Margin shows it stood at 696.38% in 2024, then slumped by 668 bps to 3953.34% in 2025, then dropped by 27 bps to 5014.49% in 2026.
- The last three FCF Margin figures came in at 5014.49% (Q1 2026), 3953.34% (Q4 2025), and 3194.45% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | FCF Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | - |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | -3.98% |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | - |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 43.35% |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 23.53% |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 4.17% |
| 10 | Prime Medicine | 601.24 Mn | 601.24 Mn | - | -5,014.49% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -5,014.49% |
| Dec 31, 2025 | -3,953.34% |
| Sep 30, 2025 | -3,194.45% |
| Jun 30, 2025 | -3,510.13% |
| Mar 31, 2025 | -3,526.75% |
| Dec 31, 2024 | 696.38% |
| Sep 30, 2024 | -12,281.34% |
| Mar 31, 2024 | -11,849.58% |