Prime Medicine (PRME) FCF Margin (2024 - 2026)
Prime Medicine (PRME) posted FCF Margin of 4989.49% for Q1 2026, down 11.36% on a QoQ basis from 4480.43% in Q4 2025, and down 146273.0% year-over-year from N/an in Q1 2025.
Prime Medicine (PRME) FCF Margin (2024 - 2026) Analysis & Trends
Prime Medicine's FCF Margin history runs 3 years deep, the most recent figure standing at 4989.49% for Q1 2026.
- Quarterly FCF Margin fell 146273.0% year-over-year to 4989.49% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 3929.75% (down 115393.0% YoY) and the FY2025 annual result came in at 3607.41%, up 55012.0% from the prior year.
- FCF Margin was 4989.49% for Q1 2026 at Prime Medicine, down from 4480.43% in the prior quarter.
- Across five years, FCF Margin topped out at 696.38% in Q4 2024 and bottomed at 11597.29% in Q1 2024.
- A 3-year average of 5128.92% and a median of 4003.59% in 2025 frame the typical range for FCF Margin.
- Peak annual rise in FCF Margin reached 807054 bps in 2025, while the deepest fall reached 517681 bps in 2025.
- Prime Medicine's FCF Margin stood at 696.38% in 2024, then sank by 743 bps to 4480.43% in 2025, then fell by 11 bps to 4989.49% in 2026.
- Business Quant data shows PRME's FCF Margin at 4989.49% in Q1 2026, 4480.43% in Q4 2025, and 3194.45% in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | FCF Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | - |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 10.45% |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | - |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 43.35% |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 23.53% |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | - |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | - |
| 10 | Prime Medicine | 525.98 Mn | 525.98 Mn | - | -4,989.49% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -4,989.49% |
| Dec 31, 2025 | -4,480.43% |
| Sep 30, 2025 | -3,194.45% |
| Jun 30, 2025 | -3,510.13% |
| Mar 31, 2025 | -3,526.75% |
| Dec 31, 2024 | 696.38% |
| Sep 30, 2024 | -10,429.19% |
| Mar 31, 2024 | -11,597.29% |