Prime Medicine PRME
NASDAQ PRME
$3.70 -0.01 (-0.27%)
As of: Sep 4, 2026 · 3:59 PM EDT

Prime Medicine (PRME) FCF Margin (2024 - 2026)

Prime Medicine's (PRME) quarterly FCF Margin came in at 4989.49% in Q1 2026, down 146273.0% YoY from N/an in Q1 2025, and down 11.36% on a QoQ basis from 4480.43% in Q4 2025.

Analysis

Prime Medicine (PRME) FCF Margin (2024 - 2026) Analysis & Trends

Prime Medicine (PRME) has 3 years of FCF Margin data on file, last reported at 4989.49% in Q1 2026.

  • Quarterly FCF Margin fell 146273.0% year-over-year to 4989.49% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 3929.75% (down 115393.0% YoY) and the FY2025 annual result came in at 3607.41%, up 55012.0% from the prior year.
  • FCF Margin slipped to 4989.49% in Q1 2026, from 4480.43% in the prior quarter.
  • In the past five years, FCF Margin ranged from a high of 696.38% in Q4 2024 to a low of 11597.29% in Q1 2024.
  • A 3-year average of 5128.92% and a median of 4003.59% in 2025 frame the typical range for FCF Margin.
  • The widest YoY moves for FCF Margin: up 807054 bps in 2025, down 517681 bps in 2025.
  • Tracing PRME's FCF Margin over 3 years: stood at 696.38% in 2024, then tumbled by 743 bps to 4480.43% in 2025, then dropped by 11 bps to 4989.49% in 2026.
  • The last three FCF Margin figures came in at 4989.49% (Q1 2026), 4480.43% (Q4 2025), and 3194.45% (Q3 2025), per Business Quant data.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) FCF Margin (Qtr)
1 Vertex Pharmaceuticals 138.47 Bn 130.62 Bn 2.84 Bn 30.39%
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn 13.35%
3 Argenx Se 63.38 Bn 58.19 Bn 1.37 Bn -
4 Moderna 58.09 Bn 52.95 Bn 52.00 Mn -388.28%
5 Revolution Medicines 44.33 Bn 44.33 Bn - -
6 BeOne Medicines 40.02 Bn 34.92 Bn 1.53 Bn 25.68%
7 Alnylam Pharmaceuticals 35.57 Bn 32.27 Bn 992.69 Mn 22.62%
8 Royalty Pharma 28.45 Bn 27.61 Bn - 70.82%
9 Insmed 27.48 Bn 26.32 Bn 358.27 Mn -22.35%
10 Prime Medicine 653.96 Mn 653.96 Mn - -3,560.83%
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -3,560.83%
Mar 31, 2026 -5,014.49%
Dec 31, 2025 -4,480.43%
Sep 30, 2025 -2,880.49%
Jun 30, 2025 -3,855.07%
Mar 31, 2025 -3,526.75%
Dec 31, 2024 662.12%
Sep 30, 2024 -13,009.09%
Mar 31, 2024 -11,849.58%