Prime Medicine (PRME) FCF Margin (2024 - 2026)
Prime Medicine's (PRME) quarterly FCF Margin came in at 4989.49% in Q1 2026, down 146273.0% YoY from N/an in Q1 2025, and down 11.36% on a QoQ basis from 4480.43% in Q4 2025.
Analysis
Prime Medicine (PRME) FCF Margin (2024 - 2026) Analysis & Trends
Prime Medicine (PRME) has 3 years of FCF Margin data on file, last reported at 4989.49% in Q1 2026.
- Quarterly FCF Margin fell 146273.0% year-over-year to 4989.49% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 3929.75% (down 115393.0% YoY) and the FY2025 annual result came in at 3607.41%, up 55012.0% from the prior year.
- FCF Margin slipped to 4989.49% in Q1 2026, from 4480.43% in the prior quarter.
- In the past five years, FCF Margin ranged from a high of 696.38% in Q4 2024 to a low of 11597.29% in Q1 2024.
- A 3-year average of 5128.92% and a median of 4003.59% in 2025 frame the typical range for FCF Margin.
- The widest YoY moves for FCF Margin: up 807054 bps in 2025, down 517681 bps in 2025.
- Tracing PRME's FCF Margin over 3 years: stood at 696.38% in 2024, then tumbled by 743 bps to 4480.43% in 2025, then dropped by 11 bps to 4989.49% in 2026.
- The last three FCF Margin figures came in at 4989.49% (Q1 2026), 4480.43% (Q4 2025), and 3194.45% (Q3 2025), per Business Quant data.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | FCF Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.47 Bn | 130.62 Bn | 2.84 Bn | 30.39% |
| 2 | Regeneron Pharmaceuticals | 85.18 Bn | 77.19 Bn | 3.93 Bn | 13.35% |
| 3 | Argenx Se | 63.38 Bn | 58.19 Bn | 1.37 Bn | - |
| 4 | Moderna | 58.09 Bn | 52.95 Bn | 52.00 Mn | -388.28% |
| 5 | Revolution Medicines | 44.33 Bn | 44.33 Bn | - | - |
| 6 | BeOne Medicines | 40.02 Bn | 34.92 Bn | 1.53 Bn | 25.68% |
| 7 | Alnylam Pharmaceuticals | 35.57 Bn | 32.27 Bn | 992.69 Mn | 22.62% |
| 8 | Royalty Pharma | 28.45 Bn | 27.61 Bn | - | 70.82% |
| 9 | Insmed | 27.48 Bn | 26.32 Bn | 358.27 Mn | -22.35% |
| 10 | Prime Medicine | 653.96 Mn | 653.96 Mn | - | -3,560.83% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -3,560.83% |
| Mar 31, 2026 | -5,014.49% |
| Dec 31, 2025 | -4,480.43% |
| Sep 30, 2025 | -2,880.49% |
| Jun 30, 2025 | -3,855.07% |
| Mar 31, 2025 | -3,526.75% |
| Dec 31, 2024 | 662.12% |
| Sep 30, 2024 | -13,009.09% |
| Mar 31, 2024 | -11,849.58% |