Prime Medicine PRME
NASDAQ PRME
$3.09 +0.21 (+7.48%)
At close: Sep 29, 2026 · 4:00 PM EDT

Prime Medicine (PRME) FCF Margin (2024 - 2026)

Updated

Prime Medicine (PRME) reported FCF Margin of -3560.83% for Q2 2026, up 294.24 percentage points from -3855.07% a year earlier and up 1453.65 percentage points from the prior quarter.

Analysis

Prime Medicine (PRME) FCF Margin (2024 - 2026) Analysis & Trends

Over the twelve months ended Jun 30, 2026, Prime Medicine's FCF Margin came in at -3850.92%, down 1694.14 percentage points year-over-year; for FY2025, it was -3607.41%, up 755.95 percentage points from FY2024.

  • FCF Margin has a five-year change of -3488.73 percentage points (FY2020 to FY2025).
  • By year, FCF Margin came in at -4363.36% in FY2024.
  • Five-year quarterly FCF Margin spans a low of -13009.09% in Q3 2024 and a high of 662.12% in Q4 2024.
  • Year over year, FCF Margin gained in three of the last five quarters, with an average year-over-year change of +2423.08 percentage points.
  • Per Business Quant data, the three quarters before Q2 2026 came in at -5014.49% (Q1 2026), -4480.43% (Q4 2025) and -2880.49% (Q3 2025).
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) FCF Margin (Qtr)
1 Johnson & Johnson 655.56 Bn 574.09 Bn 17.26 Bn 28.82%
2 AbbVie 470.94 Bn 444.10 Bn 12.70 Bn 18.33%
3 Merck 367.14 Bn 321.57 Bn 12.21 Bn 26.96%
4 Novartis Ag 280.33 Bn 236.20 Bn 11.24 Bn 43.05%
5 Astrazeneca 257.78 Bn 231.34 Bn 12.86 Bn 34.72%
6 Amgen 226.04 Bn 181.44 Bn 7.24 Bn 34.70%
7 Gilead Sciences 188.89 Bn 163.01 Bn 6.22 Bn 44.00%
8 Pfizer 163.75 Bn 110.70 Bn 10.94 Bn 2.01%
9 Vertex Pharmaceuticals 133.68 Bn 105.69 Bn 2.84 Bn 30.39%
10 Prime Medicine 520.52 Mn 520.52 Mn - -3,560.83%
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -3,560.83%
Mar 31, 2026 -5,014.49%
Dec 31, 2025 -4,480.43%
Sep 30, 2025 -2,880.49%
Jun 30, 2025 -3,855.07%
Mar 31, 2025 -3,526.75%
Dec 31, 2024 662.12%
Sep 30, 2024 -13,009.09%
Mar 31, 2024 -11,849.58%
API Access

Prime Medicine FCF Margin API

Pull this series into your own models, spreadsheets and apps with the Business Quant Historical Metrics API. The request below matches the chart above — change the frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.

https://data.businessquant.com/historic?slug=fcf-margin&ticker=PRME&period=max&api_key=YOUR_API_KEY