Prime Medicine (PRME) Return on Capital Employed (2022 - 2025)

Prime Medicine (PRME) has disclosed Return on Capital Employed for 4 consecutive years, with 0.64% as the latest value for Q4 2025.

  • For the quarter ending Q4 2025, Return on Capital Employed rose 9.0% year-over-year to 0.64%, compared with a TTM value of 0.64% through Dec 2025, up 9.0%, and an annual FY2025 reading of 0.74%, up 24.0% over the prior year.
  • Return on Capital Employed was 0.64% for Q4 2025 at Prime Medicine, up from 0.69% in the prior quarter.
  • Across five years, Return on Capital Employed topped out at 0.45% in Q4 2022 and bottomed at 1.28% in Q4 2023.
  • Average Return on Capital Employed over 4 years is 0.79%, with a median of 0.75% recorded in 2025.
  • The sharpest move saw Return on Capital Employed tumbled -83bps in 2023, then surged 55bps in 2024.
  • Year by year, Return on Capital Employed stood at 0.45% in 2022, then tumbled by -187bps to 1.28% in 2023, then soared by 43bps to 0.73% in 2024, then grew by 13bps to 0.64% in 2025.
  • Business Quant data shows Return on Capital Employed for PRME at 0.64% in Q4 2025, 0.69% in Q3 2025, and 0.76% in Q2 2025.