Prime Medicine (PRME) EBT Margin (2024 - 2026)
Prime Medicine (PRME) posted EBT Margin of -3682.58% for Q2 2026, up 1034.10 percentage points from -4716.68% a year earlier and up 2115.67 percentage points from the prior quarter.
Powered by 
Analysis
Prime Medicine (PRME) EBT Margin (2024 - 2026) Analysis & Trends
For the trailing twelve months through Jun 30, 2026, EBT Margin at Prime Medicine was -4725.93%, down 709.10 percentage points year-over-year; for FY2025, it was -4408.48%, up 2158.13 percentage points from FY2024.
- Annual EBT Margin shows a five-year change of -4378.87 percentage points (FY2020 to FY2025).
- In prior years, Prime Medicine's EBT Margin was -6566.61% in FY2024.
- The Q2 2026 figure stands as the highest quarterly EBT Margin since Q1 2025.
- On a year-over-year basis, EBT Margin increased in three of the last five quarters, with an average year-over-year change of +4007.39 percentage points.
- According to Business Quant data, EBT Margin for the three prior quarters was -5798.25% (Q1 2026), -5671.24% (Q4 2025) and -4312.82% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBT Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 645.01 Bn | 563.54 Bn | 17.26 Bn | 26.66% |
| 2 | AbbVie | 465.23 Bn | 438.39 Bn | 12.70 Bn | 25.18% |
| 3 | Merck | 368.40 Bn | 322.83 Bn | 12.21 Bn | -4.11% |
| 4 | Novartis Ag | 278.02 Bn | 233.89 Bn | 11.24 Bn | 29.63% |
| 5 | Astrazeneca | 254.57 Bn | 228.13 Bn | 12.86 Bn | 18.19% |
| 6 | Amgen | 229.02 Bn | 184.42 Bn | 7.24 Bn | 27.53% |
| 7 | Gilead Sciences | 187.74 Bn | 161.85 Bn | 6.22 Bn | -131.41% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | -4.34% |
| 9 | Vertex Pharmaceuticals | 133.45 Bn | 105.45 Bn | 2.84 Bn | 41.75% |
| 10 | Prime Medicine | 558.48 Mn | 558.48 Mn | - | -3,682.58% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -3,682.58% |
| Mar 31, 2026 | -5,798.25% |
| Dec 31, 2025 | -5,671.24% |
| Sep 30, 2025 | -4,312.82% |
| Jun 30, 2025 | -4,716.68% |
| Mar 31, 2025 | -3,568.78% |
| Dec 31, 2024 | -1,936.60% |
| Sep 30, 2024 | -25,128.23% |
| Mar 31, 2024 | -7,720.30% |
API Access
Prime Medicine EBT Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebt-margin&ticker=PRME&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebt-margin", "ticker": "PRME", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=ebt-margin&ticker=PRME&period=max&api_key=YOUR_API_KEY");
const data = await res.json();