Prime Medicine (PRME) Net Margin (2024 - 2026)
Prime Medicine (PRME) reported Net Margin of 5738.55% for Q1 2026, down 216978.0% on a YoY basis from N/an in Q1 2025, and down 4.36% quarter-over-quarter from 5498.69% in Q4 2025.
Prime Medicine (PRME) Net Margin (2024 - 2026) Analysis & Trends
Prime Medicine has reported Net Margin for 3 years, with the latest figure at 5738.55% in Q1 2026.
- For the quarter ending Q1 2026, Net Margin fell 216978.0% year-over-year to 5738.55%; the trailing twelve-month figure through Mar 2026 stood at 4917.55% (up 33495.0% YoY), and the FY2025 full-year result was 4342.44%, up 222417.0% from the prior year.
- Net Margin for Q1 2026 stood at 5738.55%, down from 5498.69% in the prior quarter.
- The five-year high for Net Margin was 1936.6% in Q4 2024, with the low at 25128.23% in Q3 2024.
- Historically, Net Margin has averaged 7307.46% across 3 years, with a median of 5107.68% in 2025.
- The largest YoY upside for Net Margin was 2099909 bps in 2025 against a maximum downside of 356209 bps in 2025.
- Prime Medicine's Net Margin stood at 1936.6% in 2024, then sank by 184 bps to 5498.69% in 2025, then dropped by 4 bps to 5738.55% in 2026.
- The last three Net Margin figures came in at 5738.55% (Q1 2026), 5498.69% (Q4 2025), and 4129.14% (Q3 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 0.82% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 34.53% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Prime Medicine | 572.02 Mn | 572.02 Mn | - | -5,738.55% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -5,738.55% |
| Dec 31, 2025 | -5,498.69% |
| Sep 30, 2025 | -4,129.14% |
| Jun 30, 2025 | -4,716.68% |
| Mar 31, 2025 | -3,568.78% |
| Dec 31, 2024 | -1,936.60% |
| Sep 30, 2024 | -25,128.23% |
| Mar 31, 2024 | -7,742.98% |