Prime Medicine PRME
NASDAQ PRME
$3.68 -0.03 (-0.81%)
As of: Sep 4, 2026 · 3:14 PM EDT

Prime Medicine (PRME) EBT (2021 - 2026)

Prime Medicine's (PRME) quarterly EBT came in at -$228.7 million in Q1 2026, down 340.77% YoY from $95.0 million in Q1 2025, and down 381.22% on a QoQ basis from -$47.5 million in Q4 2025.

Analysis

Prime Medicine (PRME) EBT (2021 - 2026) Analysis & Trends

Prime Medicine (PRME) has 6 years of EBT data on file, last reported at -$228.7 million in Q1 2026.

  • Quarterly EBT fell 340.77% year-over-year to -$228.7 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$453.2 million (down 124.21% YoY) and the FY2025 annual result came in at -$204.2 million, down 4.25% from the prior year.
  • EBT eased to -$228.7 million in Q1 2026, from -$47.5 million in the prior quarter.
  • In the past five years, EBT ranged from a high of -$24.4 million in Q1 2022 to a low of -$228.7 million in Q1 2026.
  • A 5-year average of -$60.1 million and a median of -$47.5 million in 2025 frame the typical range for EBT.
  • Annual changes were most pronounced in 2022 — EBT soared 35.85% — and 2026, when it tumbled 340.77%.
  • Tracing PRME's EBT over 5 years: stood at -$39.5 million in 2022, then plunged by 66.32% to -$65.6 million in 2023, then soared by 35.6% to -$42.3 million in 2024, then dropped by 12.42% to -$47.5 million in 2025, then slumped by 381.22% to -$228.7 million in 2026.
  • The last three EBT figures came in at -$228.7 million (Q1 2026), -$47.5 million (Q4 2025), and -$124.4 million (Q3 2025), per Business Quant data.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT (Qtr)
1 Vertex Pharmaceuticals 138.51 Bn 130.66 Bn 2.84 Bn 1.39 Bn
2 Regeneron Pharmaceuticals 85.24 Bn 77.25 Bn 3.93 Bn 1.53 Bn
3 Argenx Se 63.46 Bn 58.28 Bn 1.37 Bn 542.00 Mn
4 Moderna 57.89 Bn 52.75 Bn 52.00 Mn -767.00 Mn
5 Revolution Medicines 44.02 Bn 44.02 Bn - -644.37 Mn
6 BeOne Medicines 39.95 Bn 34.85 Bn 1.53 Bn 312.46 Mn
7 Alnylam Pharmaceuticals 35.49 Bn 32.19 Bn 992.69 Mn 177.81 Mn
8 Royalty Pharma 28.43 Bn 27.59 Bn - 81.49 Mn
9 Insmed 27.39 Bn 26.22 Bn 358.27 Mn -11.37 Mn
10 Prime Medicine 653.07 Mn 653.07 Mn - -42.50 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -42.50 Mn
Mar 31, 2026 -49.63 Mn
Dec 31, 2025 -47.53 Mn
Sep 30, 2025 -52.83 Mn
Jun 30, 2025 -52.59 Mn
Mar 31, 2025 -51.89 Mn
Dec 31, 2024 -42.28 Mn
Sep 30, 2024 -52.52 Mn
Jun 30, 2024 -55.46 Mn
Mar 31, 2024 -45.63 Mn
Dec 31, 2023 -65.64 Mn
Sep 30, 2023 -50.82 Mn
Jun 30, 2023 -42.35 Mn
Mar 31, 2023 -39.60 Mn
Dec 31, 2022 -39.47 Mn
Sep 30, 2022 -29.14 Mn
Jun 30, 2022 -29.79 Mn
Mar 31, 2022 -24.37 Mn
Dec 31, 2021 -61.53 Mn
Sep 30, 2021 -18.78 Mn