Prime Medicine PRME
NASDAQ PRME
$3.70 -0.01 (-0.27%)
As of: Sep 4, 2026 · 3:59 PM EDT

Prime Medicine (PRME) Profit After Tax (2021 - 2026)

Prime Medicine's (PRME) quarterly Profit After Tax came in at -$49.2 million in Q1 2026, up 5.2% YoY from -$46.8 million in Q1 2025, and down 6.97% on a QoQ basis from -$46.0 million in Q4 2025.

Analysis

Prime Medicine (PRME) Profit After Tax (2021 - 2026) Analysis & Trends

Prime Medicine (PRME) has 6 years of Profit After Tax data on file, last reported at -$49.2 million in Q1 2026.

  • Quarterly Profit After Tax rose 5.2% year-over-year to -$49.2 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$198.4 million (up 1.81% YoY) and the FY2025 annual result came in at -$201.1 million, down 2.64% from the prior year.
  • Profit After Tax declined to -$49.2 million in Q1 2026, from -$46.0 million in the prior quarter.
  • In the past five years, Profit After Tax ranged from a high of -$23.8 million in Q1 2022 to a low of -$65.5 million in Q4 2023.
  • A 5-year average of -$46.2 million and a median of -$49.2 million in 2026 frame the typical range for Profit After Tax.
  • Annual changes were most pronounced in 2022 — Profit After Tax sank 78.83% — and 2024, when it soared 35.47%.
  • Tracing PRME's Profit After Tax over 5 years: stood at -$59.5 million in 2022, then fell by 10.14% to -$65.5 million in 2023, then jumped by 35.47% to -$42.3 million in 2024, then decreased by 8.8% to -$46.0 million in 2025, then decreased by 6.97% to -$49.2 million in 2026.
  • The last three Profit After Tax figures came in at -$49.2 million (Q1 2026), -$46.0 million (Q4 2025), and -$50.6 million (Q3 2025), per Business Quant data.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) PAT (Qtr)
1 Vertex Pharmaceuticals 138.47 Bn 130.62 Bn 2.84 Bn 1.10 Bn
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn 1.30 Bn
3 Argenx Se 63.38 Bn 58.19 Bn 1.37 Bn 472.00 Mn
4 Moderna 58.09 Bn 52.95 Bn 52.00 Mn -782.00 Mn
5 Revolution Medicines 44.33 Bn 44.33 Bn - -644.37 Mn
6 BeOne Medicines 40.02 Bn 34.92 Bn 1.53 Bn 237.01 Mn
7 Alnylam Pharmaceuticals 35.57 Bn 32.27 Bn 992.69 Mn 164.49 Mn
8 Royalty Pharma 28.45 Bn 27.61 Bn - 81.49 Mn
9 Insmed 27.48 Bn 26.32 Bn 358.27 Mn -16.62 Mn
10 Prime Medicine 653.96 Mn 653.96 Mn - -42.12 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -42.12 Mn
Mar 31, 2026 -49.12 Mn
Dec 31, 2025 -46.08 Mn
Sep 30, 2025 -50.58 Mn
Jun 30, 2025 -52.59 Mn
Mar 31, 2025 -51.89 Mn
Dec 31, 2024 -42.28 Mn
Sep 30, 2024 -52.52 Mn
Jun 30, 2024 -55.33 Mn
Mar 31, 2024 -45.76 Mn
Dec 31, 2023 -65.64 Mn
Sep 30, 2023 -50.71 Mn
Jun 30, 2023 -42.39 Mn
Mar 31, 2023 -39.40 Mn
Dec 31, 2022 -40.60 Mn
Sep 30, 2022 -35.71 Mn
Jun 30, 2022 -29.35 Mn
Mar 31, 2022 -23.84 Mn
Dec 31, 2021 -69.27 Mn
Sep 30, 2021 -22.78 Mn