Prime Medicine (PRME) Profit After Tax (2021 - 2026)
Prime Medicine's (PRME) quarterly Profit After Tax came in at -$49.2 million in Q1 2026, up 5.2% YoY from -$46.8 million in Q1 2025, and down 6.97% on a QoQ basis from -$46.0 million in Q4 2025.
Analysis
Prime Medicine (PRME) Profit After Tax (2021 - 2026) Analysis & Trends
Prime Medicine (PRME) has 6 years of Profit After Tax data on file, last reported at -$49.2 million in Q1 2026.
- Quarterly Profit After Tax rose 5.2% year-over-year to -$49.2 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$198.4 million (up 1.81% YoY) and the FY2025 annual result came in at -$201.1 million, down 2.64% from the prior year.
- Profit After Tax declined to -$49.2 million in Q1 2026, from -$46.0 million in the prior quarter.
- In the past five years, Profit After Tax ranged from a high of -$23.8 million in Q1 2022 to a low of -$65.5 million in Q4 2023.
- A 5-year average of -$46.2 million and a median of -$49.2 million in 2026 frame the typical range for Profit After Tax.
- Annual changes were most pronounced in 2022 — Profit After Tax sank 78.83% — and 2024, when it soared 35.47%.
- Tracing PRME's Profit After Tax over 5 years: stood at -$59.5 million in 2022, then fell by 10.14% to -$65.5 million in 2023, then jumped by 35.47% to -$42.3 million in 2024, then decreased by 8.8% to -$46.0 million in 2025, then decreased by 6.97% to -$49.2 million in 2026.
- The last three Profit After Tax figures came in at -$49.2 million (Q1 2026), -$46.0 million (Q4 2025), and -$50.6 million (Q3 2025), per Business Quant data.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | PAT (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.47 Bn | 130.62 Bn | 2.84 Bn | 1.10 Bn |
| 2 | Regeneron Pharmaceuticals | 85.18 Bn | 77.19 Bn | 3.93 Bn | 1.30 Bn |
| 3 | Argenx Se | 63.38 Bn | 58.19 Bn | 1.37 Bn | 472.00 Mn |
| 4 | Moderna | 58.09 Bn | 52.95 Bn | 52.00 Mn | -782.00 Mn |
| 5 | Revolution Medicines | 44.33 Bn | 44.33 Bn | - | -644.37 Mn |
| 6 | BeOne Medicines | 40.02 Bn | 34.92 Bn | 1.53 Bn | 237.01 Mn |
| 7 | Alnylam Pharmaceuticals | 35.57 Bn | 32.27 Bn | 992.69 Mn | 164.49 Mn |
| 8 | Royalty Pharma | 28.45 Bn | 27.61 Bn | - | 81.49 Mn |
| 9 | Insmed | 27.48 Bn | 26.32 Bn | 358.27 Mn | -16.62 Mn |
| 10 | Prime Medicine | 653.96 Mn | 653.96 Mn | - | -42.12 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -42.12 Mn |
| Mar 31, 2026 | -49.12 Mn |
| Dec 31, 2025 | -46.08 Mn |
| Sep 30, 2025 | -50.58 Mn |
| Jun 30, 2025 | -52.59 Mn |
| Mar 31, 2025 | -51.89 Mn |
| Dec 31, 2024 | -42.28 Mn |
| Sep 30, 2024 | -52.52 Mn |
| Jun 30, 2024 | -55.33 Mn |
| Mar 31, 2024 | -45.76 Mn |
| Dec 31, 2023 | -65.64 Mn |
| Sep 30, 2023 | -50.71 Mn |
| Jun 30, 2023 | -42.39 Mn |
| Mar 31, 2023 | -39.40 Mn |
| Dec 31, 2022 | -40.60 Mn |
| Sep 30, 2022 | -35.71 Mn |
| Jun 30, 2022 | -29.35 Mn |
| Mar 31, 2022 | -23.84 Mn |
| Dec 31, 2021 | -69.27 Mn |
| Sep 30, 2021 | -22.78 Mn |