Prime Medicine (PRME) Profit After Tax (2021 - 2026)

Prime Medicine posted quarterly Profit After Tax of -$49.1 million for Q1 2026, up 5.33% year-on-year from -$46.6 million in Q1 2025, and down 6.6% on a QoQ basis from -$46.1 million in Q4 2025.

Prime Medicine (PRME) has 6 years of Profit After Tax data on file, last reported at -$49.1 million in Q1 2026.

  • For the quarter ending Q1 2026, Profit After Tax rose 5.33% year-over-year to -$49.1 million; the trailing twelve-month figure through Mar 2026 stood at -$198.4 million (up 1.8% YoY), and the FY2025 full-year result was -$201.1 million, down 2.69% from the prior year.
  • Profit After Tax for Q1 2026 stood at -$49.1 million, down from -$46.1 million in the prior quarter.
  • Across five years, Profit After Tax topped out at -$23.8 million in Q1 2022 and bottomed at -$65.6 million in Q4 2023.
  • The 5-year median for Profit After Tax is -$46.1 million (2025), against an average of -$45.1 million.
  • Peak annual rise in Profit After Tax reached 37.56% in 2022, while the deepest fall reached 78.83% in 2022.
  • A 5-year view of Profit After Tax shows it stood at -$39.3 million in 2022, then sank by 67.1% to -$65.6 million in 2023, then jumped by 35.6% to -$42.3 million in 2024, then slipped by 9.0% to -$46.1 million in 2025, then dropped by 6.6% to -$49.1 million in 2026.
  • The last three Profit After Tax figures came in at -$49.1 million (Q1 2026), -$46.1 million (Q4 2025), and -$50.6 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) PAT (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -2.99 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 30.90 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -14.46 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.03 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.63 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 727.20 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 205.99 Mn
10 Prime Medicine 601.24 Mn 601.24 Mn - -49.12 Mn

Historic Data

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DateValue
Mar 31, 2026 -49.12 Mn
Dec 31, 2025 -46.08 Mn
Sep 30, 2025 -50.58 Mn
Jun 30, 2025 -52.59 Mn
Mar 31, 2025 -51.89 Mn
Dec 31, 2024 -42.28 Mn
Sep 30, 2024 -52.52 Mn
Jun 30, 2024 -55.33 Mn
Mar 31, 2024 -45.76 Mn
Dec 31, 2023 -65.64 Mn
Sep 30, 2023 -50.71 Mn
Jun 30, 2023 -42.39 Mn
Mar 31, 2023 -39.40 Mn
Dec 31, 2022 -39.28 Mn
Sep 30, 2022 -29.35 Mn
Jun 30, 2022 -29.35 Mn
Mar 31, 2022 -23.84 Mn
Dec 31, 2021 -62.91 Mn
Sep 30, 2021 -16.41 Mn