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Prime Medicine (PRME) Profit After Tax (2021 - 2025)

Prime Medicine filings provide 5 years of Profit After Tax readings, the most recent being -$46.1 million for Q4 2025.

  • On a quarterly basis, Profit After Tax fell 9.0% to -$46.1 million in Q4 2025 year-over-year; TTM through Dec 2025 was -$201.1 million, a 2.69% decrease, with the full-year FY2025 number at -$201.1 million, down 2.69% from a year prior.
  • Profit After Tax hit -$46.1 million in Q4 2025 for Prime Medicine, up from -$50.6 million in the prior quarter.
  • In the past five years, Profit After Tax ranged from a high of -$16.4 million in Q3 2021 to a low of -$65.6 million in Q4 2023.
  • Median Profit After Tax over the past 5 years was -$45.9 million (2024), compared with a mean of -$44.2 million.
  • The widest YoY moves for Profit After Tax: up 37.56% in 2022, down 78.83% in 2022.
  • Prime Medicine's Profit After Tax stood at -$62.9 million in 2021, then surged by 37.56% to -$39.3 million in 2022, then tumbled by 67.1% to -$65.6 million in 2023, then surged by 35.6% to -$42.3 million in 2024, then dropped by 9.0% to -$46.1 million in 2025.
  • The last three reported values for Profit After Tax were -$46.1 million (Q4 2025), -$50.6 million (Q3 2025), and -$52.6 million (Q2 2025) per Business Quant data.