Prime Medicine (PRME) Depreciation & Amortization (CF) (2021 - 2026)

Prime Medicine posted quarterly Depreciation & Amortization (CF) of $1.9 million for Q1 2026, up 9.18% year-on-year from $1.7 million in Q1 2025, and down 1.07% on a QoQ basis from $1.9 million in Q4 2025.

Prime Medicine (PRME) has 6 years of Depreciation & Amortization (CF) data on file, last reported at $1.9 million in Q1 2026.

  • For the quarter ending Q1 2026, Depreciation & Amortization (CF) rose 9.18% year-over-year to $1.9 million; the trailing twelve-month figure through Mar 2026 stood at $7.5 million (up 14.8% YoY), and the FY2025 full-year result was $7.3 million, up 19.47% from the prior year.
  • Depreciation & Amortization (CF) for Q1 2026 stood at $1.9 million, down from $1.9 million in the prior quarter.
  • Across five years, Depreciation & Amortization (CF) topped out at $1.9 million in Q3 2025 and bottomed at $293000.0 in Q1 2022.
  • The 5-year median for Depreciation & Amortization (CF) is $1.3 million (2024), against an average of $1.3 million.
  • The widest annual swing landed in 2023, when Depreciation & Amortization (CF) soared 259.04%; it then increased 9.18% in 2026.
  • A 5-year view of Depreciation & Amortization (CF) shows it stood at $870000.0 in 2022, then soared by 43.33% to $1.2 million in 2023, then surged by 37.69% to $1.7 million in 2024, then gained by 9.26% to $1.9 million in 2025, then fell by 1.07% to $1.9 million in 2026.
  • The last three Depreciation & Amortization (CF) figures came in at $1.9 million (Q1 2026), $1.9 million (Q4 2025), and $1.9 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Depreciation & Amortization (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - 1,395.22
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 55.90 Mn
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 123.20 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 13.55 Mn
10 Prime Medicine 601.24 Mn 601.24 Mn - 1.86 Mn

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 1.86 Mn
Mar 31, 2026 1.86 Mn
Dec 31, 2025 1.88 Mn
Dec 31, 2025 1.88 Mn
Sep 30, 2025 1.88 Mn
Sep 30, 2025 1.88 Mn
Jun 30, 2025 1.86 Mn
Jun 30, 2025 1.86 Mn
Mar 31, 2025 1.70 Mn
Mar 31, 2025 1.70 Mn
Dec 31, 2024 1.72 Mn
Dec 31, 2024 1.72 Mn
Sep 30, 2024 1.56 Mn
Sep 30, 2024 1.56 Mn
Jun 30, 2024 1.54 Mn
Jun 30, 2024 1.54 Mn
Mar 31, 2024 1.32 Mn
Mar 31, 2024 1.32 Mn
Dec 31, 2023 1.25 Mn
Dec 31, 2023 1.25 Mn
Sep 30, 2023 1.24 Mn
Sep 30, 2023 1.24 Mn
Jun 30, 2023 1.12 Mn
Jun 30, 2023 1.12 Mn
Mar 31, 2023 1.05 Mn
Mar 31, 2023 1.05 Mn
Dec 31, 2022 870,000.00
Dec 31, 2022 870,000.00
Sep 30, 2022 631,000.00
Sep 30, 2022 631,000.00
Jun 30, 2022 430,000.00
Jun 30, 2022 430,000.00
Mar 31, 2022 293,000.00
Mar 31, 2022 293,000.00
Dec 31, 2021 261,000.00
Dec 31, 2021 261,000.00
Sep 30, 2021 200,000.00
Sep 30, 2021 200,000.00