Prime Medicine (PRME) Equity Average (2021 - 2026)
Prime Medicine posted quarterly Equity Average of $98.8 million for Q1 2026, down 24.03% year-on-year from $130.0 million in Q1 2025, and down 30.11% on a QoQ basis from $141.3 million in Q4 2025.
Prime Medicine (PRME) has 6 years of Equity Average data on file, last reported at $98.8 million in Q1 2026.
- For the quarter ending Q1 2026, Equity Average fell 24.03% year-over-year to $98.8 million; the trailing twelve-month figure through Mar 2026 stood at $98.8 million (down 24.03% YoY), and the FY2025 full-year result was $137.0 million, down 4.26% from the prior year.
- Equity Average for Q1 2026 stood at $98.8 million, down from $141.3 million in the prior quarter.
- Across five years, Equity Average topped out at $297.5 million in Q1 2023 and bottomed at -$209.1 million in Q3 2022.
- The 5-year median for Equity Average is $141.3 million (2025), against an average of $104.2 million.
- The widest annual swing landed in 2023, when Equity Average soared 284.13%; it then plunged 61.9% in 2025.
- A 5-year view of Equity Average shows it stood at $46.6 million in 2022, then jumped by 250.99% to $163.5 million in 2023, then rose by 4.78% to $171.3 million in 2024, then retreated by 17.5% to $141.3 million in 2025, then plunged by 30.11% to $98.8 million in 2026.
- The last three Equity Average figures came in at $98.8 million (Q1 2026), $141.3 million (Q4 2025), and $111.3 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Equity Avg. (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | 3.76 Mn |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | - |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | 21.35 Mn |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 19.01 Bn |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 31.34 Bn |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 932.28 Mn |
| 10 | Prime Medicine | 601.24 Mn | 601.24 Mn | - | 98.78 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 98.78 Mn |
| Dec 31, 2025 | 141.34 Mn |
| Sep 30, 2025 | 111.34 Mn |
| Jun 30, 2025 | 83.89 Mn |
| Mar 31, 2025 | 130.04 Mn |
| Dec 31, 2024 | 171.33 Mn |
| Sep 30, 2024 | 193.05 Mn |
| Jun 30, 2024 | 220.18 Mn |
| Mar 31, 2024 | 188.42 Mn |
| Dec 31, 2023 | 163.51 Mn |
| Sep 30, 2023 | 217.03 Mn |
| Jun 30, 2023 | 259.45 Mn |
| Mar 31, 2023 | 297.54 Mn |
| Dec 31, 2022 | 46.59 Mn |
| Sep 30, 2022 | -209.08 Mn |
| Jun 30, 2022 | -181.00 Mn |
| Mar 31, 2022 | -161.59 Mn |
| Dec 31, 2021 | -125.33 Mn |