Prime Medicine (PRME) Equity Average (2021 - 2026)

Prime Medicine posted quarterly Equity Average of $98.8 million for Q1 2026, down 24.03% year-on-year from $130.0 million in Q1 2025, and down 30.11% on a QoQ basis from $141.3 million in Q4 2025.

Prime Medicine (PRME) has 6 years of Equity Average data on file, last reported at $98.8 million in Q1 2026.

  • For the quarter ending Q1 2026, Equity Average fell 24.03% year-over-year to $98.8 million; the trailing twelve-month figure through Mar 2026 stood at $98.8 million (down 24.03% YoY), and the FY2025 full-year result was $137.0 million, down 4.26% from the prior year.
  • Equity Average for Q1 2026 stood at $98.8 million, down from $141.3 million in the prior quarter.
  • Across five years, Equity Average topped out at $297.5 million in Q1 2023 and bottomed at -$209.1 million in Q3 2022.
  • The 5-year median for Equity Average is $141.3 million (2025), against an average of $104.2 million.
  • The widest annual swing landed in 2023, when Equity Average soared 284.13%; it then plunged 61.9% in 2025.
  • A 5-year view of Equity Average shows it stood at $46.6 million in 2022, then jumped by 250.99% to $163.5 million in 2023, then rose by 4.78% to $171.3 million in 2024, then retreated by 17.5% to $141.3 million in 2025, then plunged by 30.11% to $98.8 million in 2026.
  • The last three Equity Average figures came in at $98.8 million (Q1 2026), $141.3 million (Q4 2025), and $111.3 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Equity Avg. (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - 3.76 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - 21.35 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 19.01 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 31.34 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 932.28 Mn
10 Prime Medicine 601.24 Mn 601.24 Mn - 98.78 Mn

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 98.78 Mn
Dec 31, 2025 141.34 Mn
Sep 30, 2025 111.34 Mn
Jun 30, 2025 83.89 Mn
Mar 31, 2025 130.04 Mn
Dec 31, 2024 171.33 Mn
Sep 30, 2024 193.05 Mn
Jun 30, 2024 220.18 Mn
Mar 31, 2024 188.42 Mn
Dec 31, 2023 163.51 Mn
Sep 30, 2023 217.03 Mn
Jun 30, 2023 259.45 Mn
Mar 31, 2023 297.54 Mn
Dec 31, 2022 46.59 Mn
Sep 30, 2022 -209.08 Mn
Jun 30, 2022 -181.00 Mn
Mar 31, 2022 -161.59 Mn
Dec 31, 2021 -125.33 Mn