Prime Medicine (PRME) Change in Acquisitions & Divestments (2021 - 2026)
Prime Medicine posted quarterly Change in Acquisitions & Divestments of $50.9 million for Q1 2026, up 1596.27% year-on-year from $3.0 million in Q1 2025, and up 30.15% on a QoQ basis from $39.1 million in Q4 2025.
Prime Medicine (PRME) has 6 years of Change in Acquisitions & Divestments data on file, last reported at $50.9 million in Q1 2026.
- For the quarter ending Q1 2026, Change in Acquisitions & Divestments rose 1596.27% year-over-year to $50.9 million; the trailing twelve-month figure through Mar 2026 stood at $143.7 million (up 6.66% YoY), and the FY2025 full-year result was $95.8 million, down 53.09% from the prior year.
- Change in Acquisitions & Divestments for Q1 2026 stood at $50.9 million, up from $39.1 million in the prior quarter.
- Across five years, Change in Acquisitions & Divestments topped out at $72.5 million in Q1 2024 and bottomed at $3.0 million in Q1 2025.
- The 5-year median for Change in Acquisitions & Divestments is $32.9 million (2024), against an average of $33.9 million.
- The widest annual swing landed in 2025, when Change in Acquisitions & Divestments sank 95.86%; it then jumped 1596.27% in 2026.
- A 5-year view of Change in Acquisitions & Divestments shows it stood at $25.0 million in 2022, then soared by 90.14% to $47.5 million in 2023, then slumped by 30.79% to $32.9 million in 2024, then advanced by 18.84% to $39.1 million in 2025, then soared by 30.15% to $50.9 million in 2026.
- The last three Change in Acquisitions & Divestments figures came in at $50.9 million (Q1 2026), $39.1 million (Q4 2025), and $42.4 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn |
| 10 | Prime Medicine | 601.24 Mn | 601.24 Mn | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 50.89 Mn |
| Mar 31, 2026 | 50.89 Mn |
| Dec 31, 2025 | 39.10 Mn |
| Dec 31, 2025 | 39.10 Mn |
| Sep 30, 2025 | 42.43 Mn |
| Sep 30, 2025 | 42.43 Mn |
| Jun 30, 2025 | 11.25 Mn |
| Jun 30, 2025 | 11.25 Mn |
| Mar 31, 2025 | 3.00 Mn |
| Mar 31, 2025 | 3.00 Mn |
| Dec 31, 2024 | 32.90 Mn |
| Dec 31, 2024 | 32.90 Mn |
| Sep 30, 2024 | 61.30 Mn |
| Sep 30, 2024 | 61.30 Mn |
| Jun 30, 2024 | 37.50 Mn |
| Jun 30, 2024 | 37.50 Mn |
| Mar 31, 2024 | 72.50 Mn |
| Mar 31, 2024 | 72.50 Mn |
| Dec 31, 2023 | 47.54 Mn |
| Dec 31, 2023 | 47.54 Mn |
| Sep 30, 2023 | 20.02 Mn |
| Sep 30, 2023 | 20.02 Mn |
| Jun 30, 2023 | 30.00 Mn |
| Jun 30, 2023 | 30.00 Mn |
| Mar 31, 2023 | 35.00 Mn |
| Mar 31, 2023 | 35.00 Mn |
| Dec 31, 2022 | 25.00 Mn |
| Dec 31, 2022 | 25.00 Mn |
| Sep 30, 2022 | 6.00 Mn |
| Sep 30, 2022 | 6.00 Mn |
| Jun 30, 2022 | 29.50 Mn |
| Jun 30, 2022 | 29.50 Mn |
| Mar 31, 2022 | 32.50 Mn |
| Mar 31, 2022 | 32.50 Mn |
| Dec 31, 2021 | 13.00 Mn |
| Dec 31, 2021 | 13.00 Mn |