Prime Medicine (PRME) Change in Acquisitions & Divestments (2021 - 2026)

Prime Medicine (PRME) posted Change in Acquisitions & Divestments of $50.9 million for Q1 2026, up 30.15% on a QoQ basis from $39.1 million in Q4 2025, and up 1596.27% year-over-year from $3.0 million in Q1 2025.

Prime Medicine (PRME) Change in Acquisitions & Divestments (2021 - 2026) Analysis & Trends

Prime Medicine's Change in Acquisitions & Divestments history runs 6 years deep, the most recent figure standing at $50.9 million for Q1 2026.

  • Quarterly Change in Acquisitions & Divestments rose 1596.27% year-over-year to $50.9 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $143.7 million (up 306.72% YoY) and the FY2025 annual result came in at $95.8 million, changed N/A from the prior year.
  • Change in Acquisitions & Divestments was $50.9 million for Q1 2026 at Prime Medicine, up from $39.1 million in the prior quarter.
  • Across five years, Change in Acquisitions & Divestments topped out at $72.5 million in Q1 2024 and bottomed at -$171.3 million in Q4 2024.
  • A 5-year average of $21.9 million and a median of $32.5 million in 2022 frame the typical range for Change in Acquisitions & Divestments.
  • Annual changes were most pronounced in 2024 — Change in Acquisitions & Divestments tumbled 460.37% — and 2026, when it jumped 1596.27%.
  • Prime Medicine's Change in Acquisitions & Divestments stood at $25.0 million in 2022, then jumped by 90.14% to $47.5 million in 2023, then tumbled by 460.37% to -$171.3 million in 2024, then soared by 122.83% to $39.1 million in 2025, then jumped by 30.15% to $50.9 million in 2026.
  • Business Quant data shows PRME's Change in Acquisitions & Divestments at $50.9 million in Q1 2026, $39.1 million in Q4 2025, and $42.4 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Oculis Holding AG 67,042.03 Bn 67,041.74 Bn -
2 Nanobiotix 1,908.00 Bn 1,907.94 Bn -
3 Akari Therapeutics 959.56 Bn 959.56 Bn -
4 BeOne Medicines 471.84 Bn 467.05 Bn 1.35 Bn
5 Vertex Pharmaceuticals 122.13 Bn 114.88 Bn 2.59 Bn
6 Regeneron Pharmaceuticals 70.01 Bn 61.26 Bn 3.31 Bn
7 Belite Bio 62.34 Bn 62.34 Bn -
8 Argenx Se 55.93 Bn 50.74 Bn 1.41 Bn
9 Alnylam Pharmaceuticals 37.49 Bn 34.48 Bn 959.66 Mn
10 Prime Medicine 542.80 Mn 542.80 Mn -

Historic Data

Download Data
DateValue
Mar 31, 2026 50.89 Mn
Mar 31, 2026 50.89 Mn
Dec 31, 2025 39.10 Mn
Dec 31, 2025 39.10 Mn
Sep 30, 2025 42.43 Mn
Sep 30, 2025 42.43 Mn
Jun 30, 2025 11.25 Mn
Jun 30, 2025 11.25 Mn
Mar 31, 2025 3.00 Mn
Mar 31, 2025 3.00 Mn
Dec 31, 2024 -171.30 Mn
Dec 31, 2024 -171.30 Mn
Sep 30, 2024 61.30 Mn
Sep 30, 2024 61.30 Mn
Jun 30, 2024 37.50 Mn
Jun 30, 2024 37.50 Mn
Mar 31, 2024 72.50 Mn
Mar 31, 2024 72.50 Mn
Dec 31, 2023 47.54 Mn
Dec 31, 2023 47.54 Mn