Prime Medicine (PRME) Change in Acquisitions & Divestments (2021 - 2026)

Prime Medicine posted quarterly Change in Acquisitions & Divestments of $50.9 million for Q1 2026, up 1596.27% year-on-year from $3.0 million in Q1 2025, and up 30.15% on a QoQ basis from $39.1 million in Q4 2025.

Prime Medicine (PRME) has 6 years of Change in Acquisitions & Divestments data on file, last reported at $50.9 million in Q1 2026.

  • For the quarter ending Q1 2026, Change in Acquisitions & Divestments rose 1596.27% year-over-year to $50.9 million; the trailing twelve-month figure through Mar 2026 stood at $143.7 million (up 6.66% YoY), and the FY2025 full-year result was $95.8 million, down 53.09% from the prior year.
  • Change in Acquisitions & Divestments for Q1 2026 stood at $50.9 million, up from $39.1 million in the prior quarter.
  • Across five years, Change in Acquisitions & Divestments topped out at $72.5 million in Q1 2024 and bottomed at $3.0 million in Q1 2025.
  • The 5-year median for Change in Acquisitions & Divestments is $32.9 million (2024), against an average of $33.9 million.
  • The widest annual swing landed in 2025, when Change in Acquisitions & Divestments sank 95.86%; it then jumped 1596.27% in 2026.
  • A 5-year view of Change in Acquisitions & Divestments shows it stood at $25.0 million in 2022, then soared by 90.14% to $47.5 million in 2023, then slumped by 30.79% to $32.9 million in 2024, then advanced by 18.84% to $39.1 million in 2025, then soared by 30.15% to $50.9 million in 2026.
  • The last three Change in Acquisitions & Divestments figures came in at $50.9 million (Q1 2026), $39.1 million (Q4 2025), and $42.4 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn -
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn -
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn
7 Evaxion A 62.56 Bn 62.54 Bn -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn
10 Prime Medicine 601.24 Mn 601.24 Mn -

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 50.89 Mn
Mar 31, 2026 50.89 Mn
Dec 31, 2025 39.10 Mn
Dec 31, 2025 39.10 Mn
Sep 30, 2025 42.43 Mn
Sep 30, 2025 42.43 Mn
Jun 30, 2025 11.25 Mn
Jun 30, 2025 11.25 Mn
Mar 31, 2025 3.00 Mn
Mar 31, 2025 3.00 Mn
Dec 31, 2024 32.90 Mn
Dec 31, 2024 32.90 Mn
Sep 30, 2024 61.30 Mn
Sep 30, 2024 61.30 Mn
Jun 30, 2024 37.50 Mn
Jun 30, 2024 37.50 Mn
Mar 31, 2024 72.50 Mn
Mar 31, 2024 72.50 Mn
Dec 31, 2023 47.54 Mn
Dec 31, 2023 47.54 Mn
Sep 30, 2023 20.02 Mn
Sep 30, 2023 20.02 Mn
Jun 30, 2023 30.00 Mn
Jun 30, 2023 30.00 Mn
Mar 31, 2023 35.00 Mn
Mar 31, 2023 35.00 Mn
Dec 31, 2022 25.00 Mn
Dec 31, 2022 25.00 Mn
Sep 30, 2022 6.00 Mn
Sep 30, 2022 6.00 Mn
Jun 30, 2022 29.50 Mn
Jun 30, 2022 29.50 Mn
Mar 31, 2022 32.50 Mn
Mar 31, 2022 32.50 Mn
Dec 31, 2021 13.00 Mn
Dec 31, 2021 13.00 Mn