Prime Medicine (PRME) Net Cash Flow (2021 - 2025)

Prime Medicine filings provide 5 years of Net Cash Flow readings, the most recent being -$8.4 million for Q4 2025.

  • On a quarterly basis, Net Cash Flow fell 112.97% to -$8.4 million in Q4 2025 year-over-year; TTM through Dec 2025 was -$119.8 million, a 184.69% decrease, with the full-year FY2025 number at -$119.8 million, down 184.69% from a year prior.
  • Net Cash Flow hit -$8.4 million in Q4 2025 for Prime Medicine, down from $17.6 million in the prior quarter.
  • In the past five years, Net Cash Flow ranged from a high of $139.7 million in Q4 2022 to a low of -$90.6 million in Q1 2025.
  • Median Net Cash Flow over the past 5 years was -$12.9 million (2023), compared with a mean of -$7.3 million.
  • Biggest five-year swings in Net Cash Flow: surged 6691.46% in 2022 and later tumbled 272.28% in 2025.
  • Prime Medicine's Net Cash Flow stood at -$2.1 million in 2021, then surged by 6691.46% to $139.7 million in 2022, then plummeted by 101.71% to -$2.4 million in 2023, then soared by 2804.36% to $64.5 million in 2024, then crashed by 112.97% to -$8.4 million in 2025.
  • The last three reported values for Net Cash Flow were -$8.4 million (Q4 2025), $17.6 million (Q3 2025), and -$38.4 million (Q2 2025) per Business Quant data.