Prime Medicine PRME
NASDAQ PRME
$3.70 -0.01 (-0.27%)
As of: Sep 4, 2026 · 3:59 PM EDT

Prime Medicine (PRME) Net Cash Flow (2021 - 2026)

Prime Medicine's (PRME) quarterly Net Cash Flow came in at $1.1 million in Q1 2026, up 101.19% YoY from $533835.8 in Q1 2025, and up 112.84% on a QoQ basis from -$8.4 million in Q4 2025.

Analysis

Prime Medicine (PRME) Net Cash Flow (2021 - 2026) Analysis & Trends

Prime Medicine (PRME) has 6 years of Net Cash Flow data on file, last reported at $1.1 million in Q1 2026.

  • Quarterly Net Cash Flow rose 101.19% year-over-year to $1.1 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$28.1 million (down 1537.11% YoY) and the FY2025 annual result came in at -$119.8 million, down 184.69% from the prior year.
  • Net Cash Flow grew to $1.1 million in Q1 2026, from -$8.4 million in the prior quarter.
  • In the past five years, Net Cash Flow ranged from a high of $139.7 million in Q4 2022 to a low of -$90.6 million in Q1 2025.
  • A 5-year average of -$7.1 million and a median of -$12.9 million in 2023 frame the typical range for Net Cash Flow.
  • Annual changes were most pronounced in 2022 — Net Cash Flow soared 6691.46% — and 2025, when it sank 272.28%.
  • Tracing PRME's Net Cash Flow over 5 years: stood at $139.7 million in 2022, then sank by 101.71% to -$2.4 million in 2023, then jumped by 2804.36% to $64.5 million in 2024, then plunged by 112.97% to -$8.4 million in 2025, then soared by 112.84% to $1.1 million in 2026.
  • The last three Net Cash Flow figures came in at $1.1 million (Q1 2026), -$8.4 million (Q4 2025), and $17.6 million (Q3 2025), per Business Quant data.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Cash Flow (Qtr)
1 Vertex Pharmaceuticals 138.47 Bn 130.62 Bn 2.84 Bn 652.90 Mn
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn -504.30 Mn
3 Argenx Se 63.38 Bn 58.19 Bn 1.37 Bn -
4 Moderna 58.09 Bn 52.95 Bn 52.00 Mn -183.00 Mn
5 Revolution Medicines 44.33 Bn 44.33 Bn - 374.50 Mn
6 BeOne Medicines 40.02 Bn 34.92 Bn 1.53 Bn 407.41 Mn
7 Alnylam Pharmaceuticals 35.57 Bn 32.27 Bn 992.69 Mn -496,000.00
8 Royalty Pharma 28.45 Bn 27.61 Bn - 225.59 Mn
9 Insmed 27.48 Bn 26.32 Bn 358.27 Mn -37.14 Mn
10 Prime Medicine 653.96 Mn 653.96 Mn - -16.66 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -16.66 Mn
Mar 31, 2026 1.07 Mn
Dec 31, 2025 -8.36 Mn
Sep 30, 2025 17.59 Mn
Jun 30, 2025 -38.44 Mn
Mar 31, 2025 -90.60 Mn
Dec 31, 2024 64.50 Mn
Sep 30, 2024 62.94 Mn
Jun 30, 2024 -38.56 Mn
Mar 31, 2024 52.59 Mn
Dec 31, 2023 -2.39 Mn
Sep 30, 2023 -76.62 Mn
Jun 30, 2023 -12.89 Mn
Mar 31, 2023 -54.16 Mn
Dec 31, 2022 139.67 Mn
Sep 30, 2022 -44.29 Mn
Jun 30, 2022 -71.64 Mn
Mar 31, 2022 -21.17 Mn
Dec 31, 2021 -2.12 Mn