Prime Medicine (PRME) Net Cash Flow (2021 - 2026)
Prime Medicine (PRME) posted Net Cash Flow of $1.1 million for Q1 2026, up 112.84% on a QoQ basis from -$8.4 million in Q4 2025, and up 101.19% year-over-year from $533835.8 in Q1 2025.
Prime Medicine (PRME) Net Cash Flow (2021 - 2026) Analysis & Trends
Prime Medicine's Net Cash Flow history runs 6 years deep, the most recent figure standing at $1.1 million for Q1 2026.
- Quarterly Net Cash Flow rose 101.19% year-over-year to $1.1 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$28.1 million (down 1537.11% YoY) and the FY2025 annual result came in at -$119.8 million, down 184.69% from the prior year.
- Net Cash Flow was $1.1 million for Q1 2026 at Prime Medicine, up from -$8.4 million in the prior quarter.
- Across five years, Net Cash Flow topped out at $139.7 million in Q4 2022 and bottomed at -$90.6 million in Q1 2025.
- A 5-year average of -$7.1 million and a median of -$12.9 million in 2023 frame the typical range for Net Cash Flow.
- Annual changes were most pronounced in 2022 — Net Cash Flow soared 6691.46% — and 2025, when it plunged 272.28%.
- Prime Medicine's Net Cash Flow stood at $139.7 million in 2022, then tumbled by 101.71% to -$2.4 million in 2023, then soared by 2804.36% to $64.5 million in 2024, then slumped by 112.97% to -$8.4 million in 2025, then surged by 112.84% to $1.1 million in 2026.
- Business Quant data shows PRME's Net Cash Flow at $1.1 million in Q1 2026, -$8.4 million in Q4 2025, and $17.6 million in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Cash Flow (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | 10.56 Mn |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 224.46 Mn |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | -1.34 Mn |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 457.40 Mn |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | -152.20 Mn |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | - |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | 57.19 Mn |
| 10 | Prime Medicine | 525.98 Mn | 525.98 Mn | - | 1.07 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 1.07 Mn |
| Mar 31, 2026 | 1.07 Mn |
| Dec 31, 2025 | -8.36 Mn |
| Dec 31, 2025 | -8.36 Mn |
| Sep 30, 2025 | 17.59 Mn |
| Sep 30, 2025 | 17.59 Mn |
| Jun 30, 2025 | -38.44 Mn |
| Jun 30, 2025 | -38.44 Mn |
| Mar 31, 2025 | -90.60 Mn |
| Mar 31, 2025 | -90.60 Mn |
| Dec 31, 2024 | 64.50 Mn |
| Dec 31, 2024 | 64.50 Mn |
| Sep 30, 2024 | 62.94 Mn |
| Sep 30, 2024 | 62.94 Mn |
| Jun 30, 2024 | -38.56 Mn |
| Jun 30, 2024 | -38.56 Mn |
| Mar 31, 2024 | 52.59 Mn |
| Mar 31, 2024 | 52.59 Mn |
| Dec 31, 2023 | -2.39 Mn |
| Dec 31, 2023 | -2.39 Mn |