Prime Medicine (PRME) Operating Income (2021 - 2026)

Prime Medicine has reported Operating Income for 6 years, with the latest figure at -$50.7 million in Q1 2026.

• For the quarter ending Q1 2026, Operating Income rose 3.32% year-over-year to -$50.7 million; the trailing twelve-month figure through Mar 2026 stood at -$206.6 million (changed 0.05% YoY), and the FY2025 full-year result was -$208.4 million, down 2.91% from the prior year.
• Operating Income for Q1 2026 stood at -$50.7 million, down from -$48.6 million in the prior quarter.
• The five-year high for Operating Income was -$19.9 million in Q1 2022, with the low at -$68.0 million in Q4 2023.
• Historically, Operating Income has averaged -$46.0 million across 5 years, with a median of -$48.6 million in 2025.
• The largest YoY upside for Operating Income was 35.6% in 2022 against a maximum downside of 203.59% in 2022.
• Prime Medicine's Operating Income stood at -$38.7 million in 2022, then plunged by 75.89% to -$68.0 million in 2023, then soared by 35.01% to -$44.2 million in 2024, then decreased by 9.92% to -$48.6 million in 2025, then dropped by 4.21% to -$50.7 million in 2026.
• The last three Operating Income figures came in at -$50.7 million (Q1 2026), -$48.6 million (Q4 2025), and -$54.0 million (Q3 2025), per Business Quant data.