Prime Medicine (PRME) Operating Income (2021 - 2026)
Prime Medicine (PRME) reported Operating Income of -$43.29 million for Q2 2026, compared with -$53.38 million a year earlier.
Prime Medicine (PRME) Operating Income (2021 - 2026) Analysis & Trends
Over the twelve months ended Jun 30, 2026, Prime Medicine's Operating Income came in at -$196.52 million; for FY2025, it was -$208.35 million.
- By year, Operating Income came in at -$202.47 million in FY2024, -$204.79 million in FY2023, -$116.54 million in FY2022 and -$84.47 million in FY2021.
- The Q2 2026 figure ranks as the highest quarterly Operating Income since Q1 2023.
- Per Business Quant data, the three quarters before Q2 2026 came in at -$50.65 million (Q1 2026), -$48.61 million (Q4 2025) and -$53.97 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn | 8.41 Bn |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn | 6.18 Bn |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn | 6.27 Bn |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn | 5.56 Bn |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn | 4.39 Bn |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn | 3.71 Bn |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn | 3.46 Bn |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn | 5.47 Bn |
| 10 | Prime Medicine | 704.88 Mn | 469.45 Mn | - | -43.29 Mn |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -43.29 Mn |
| Mar 31, 2026 | -50.65 Mn |
| Sep 30, 2025 | -53.97 Mn |
| Jun 30, 2025 | -53.38 Mn |
| Mar 31, 2025 | -52.39 Mn |
| Dec 31, 2024 | -44.22 Mn |
| Sep 30, 2024 | -54.23 Mn |
| Jun 30, 2024 | -55.67 Mn |
| Mar 31, 2024 | -48.34 Mn |
| Dec 31, 2023 | -68.04 Mn |
| Sep 30, 2023 | -51.46 Mn |
| Jun 30, 2023 | -45.26 Mn |
| Mar 31, 2023 | -40.03 Mn |
| Dec 31, 2022 | -38.69 Mn |
| Sep 30, 2022 | -31.66 Mn |
| Jun 30, 2022 | -26.31 Mn |
| Mar 31, 2022 | -19.90 Mn |
| Dec 31, 2021 | -60.08 Mn |
| Sep 30, 2021 | -10.43 Mn |
Prime Medicine Operating Income API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-income&ticker=PRME&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-income", "ticker": "PRME", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=operating-income&ticker=PRME&period=max&api_key=YOUR_API_KEY");
const data = await res.json();