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Prime Medicine (PRME) Free Cash Flow (2021 - 2025)

Prime Medicine filings provide 5 years of Free Cash Flow readings, the most recent being -$33.1 million for Q4 2025.

  • On a quarterly basis, Free Cash Flow fell 260.87% to -$33.1 million in Q4 2025 year-over-year; TTM through Dec 2025 was -$162.7 million, a 31.17% decrease, with the full-year FY2025 number at -$162.7 million, down 31.17% from a year prior.
  • Free Cash Flow hit -$33.1 million in Q4 2025 for Prime Medicine, up from -$35.3 million in the prior quarter.
  • In the past five years, Free Cash Flow ranged from a high of $20.6 million in Q4 2024 to a low of -$68.5 million in Q1 2024.
  • Median Free Cash Flow over the past 5 years was -$35.7 million (2023), compared with a mean of -$35.5 million.
  • Biggest five-year swings in Free Cash Flow: soared 139.55% in 2024 and later crashed 260.87% in 2025.
  • Prime Medicine's Free Cash Flow stood at -$10.2 million in 2021, then tumbled by 202.88% to -$30.8 million in 2022, then crashed by 69.01% to -$52.1 million in 2023, then surged by 139.55% to $20.6 million in 2024, then crashed by 260.87% to -$33.1 million in 2025.
  • The last three reported values for Free Cash Flow were -$33.1 million (Q4 2025), -$35.3 million (Q3 2025), and -$43.0 million (Q2 2025) per Business Quant data.