Prime Medicine (PRME) Leases (2021 - 2026)

Prime Medicine posted quarterly Leases of $123.3 million for Q1 2026, up 1661.91% year-on-year from $7.0 million in Q1 2025, and down 2.25% on a QoQ basis from $126.2 million in Q4 2025.

Prime Medicine (PRME) has 6 years of Leases data on file, last reported at $123.3 million in Q1 2026.

  • For the quarter ending Q1 2026, Leases rose 1661.91% year-over-year to $123.3 million; the trailing twelve-month figure through Mar 2026 stood at $123.3 million (up 1661.91% YoY), and the FY2025 full-year result was $126.2 million, up 167.57% from the prior year.
  • Leases for Q1 2026 stood at $123.3 million, down from $126.2 million in the prior quarter.
  • Across five years, Leases topped out at $126.2 million in Q4 2025 and bottomed at $7.0 million in Q1 2025.
  • The 5-year median for Leases is $32.3 million (2022), against an average of $52.9 million.
  • The widest annual swing landed in 2025, when Leases slumped 84.41%; it then jumped 1661.91% in 2026.
  • A 5-year view of Leases shows it stood at $29.5 million in 2022, then sank by 52.81% to $13.9 million in 2023, then soared by 238.25% to $47.2 million in 2024, then soared by 167.57% to $126.2 million in 2025, then decreased by 2.25% to $123.3 million in 2026.
  • The last three Leases figures came in at $123.3 million (Q1 2026), $126.2 million (Q4 2025), and $117.9 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Leases (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - 83,048.00
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - 61,822.50
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 285.20 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.69 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn -
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 189.30 Mn
10 Prime Medicine 601.24 Mn 601.24 Mn - 123.33 Mn

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 123.33 Mn
Dec 31, 2025 126.18 Mn
Sep 30, 2025 117.87 Mn
Jun 30, 2025 120.20 Mn
Mar 31, 2025 7.00 Mn
Dec 31, 2024 47.16 Mn
Sep 30, 2024 49.36 Mn
Jun 30, 2024 11.30 Mn
Mar 31, 2024 44.90 Mn
Dec 31, 2023 13.94 Mn
Sep 30, 2023 17.27 Mn
Jun 30, 2023 26.51 Mn
Mar 31, 2023 26.71 Mn
Dec 31, 2022 29.55 Mn
Sep 30, 2022 32.34 Mn
Dec 31, 2021 10.75 Mn