Prime Medicine (PRME) EBT Margin (2024 - 2026)
Prime Medicine (PRME) reported EBT Margin of 5798.25% for Q1 2026, down 222947.0% on a YoY basis from N/an in Q1 2025, and down 2.24% quarter-over-quarter from 5671.24% in Q4 2025.
Prime Medicine (PRME) EBT Margin (2024 - 2026) Analysis & Trends
Prime Medicine has reported EBT Margin for 3 years, with the latest figure at 5798.25% in Q1 2026.
- For the quarter ending Q1 2026, EBT Margin fell 222947.0% year-over-year to 5798.25%; the trailing twelve-month figure through Mar 2026 stood at 5021.84% (up 23414.0% YoY), and the FY2025 full-year result was 4408.48%, up 215813.0% from the prior year.
- EBT Margin for Q1 2026 stood at 5798.25%, down from 5671.24% in the prior quarter.
- The five-year high for EBT Margin was 1936.6% in Q4 2024, with the low at 25128.23% in Q3 2024.
- Historically, EBT Margin has averaged 7356.61% across 3 years, with a median of 5193.96% in 2025.
- The largest YoY upside for EBT Margin was 2081541 bps in 2025 against a maximum downside of 373464 bps in 2025.
- Prime Medicine's EBT Margin stood at 1936.6% in 2024, then tumbled by 193 bps to 5671.24% in 2025, then decreased by 2 bps to 5798.25% in 2026.
- The last three EBT Margin figures came in at 5798.25% (Q1 2026), 5671.24% (Q4 2025), and 4312.82% (Q3 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBT Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 6.40% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 41.95% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Prime Medicine | 572.02 Mn | 572.02 Mn | - | -5,798.25% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -5,798.25% |
| Dec 31, 2025 | -5,671.24% |
| Sep 30, 2025 | -4,312.82% |
| Jun 30, 2025 | -4,716.68% |
| Mar 31, 2025 | -3,568.78% |
| Dec 31, 2024 | -1,936.60% |
| Sep 30, 2024 | -25,128.23% |
| Mar 31, 2024 | -7,720.30% |