Prime Medicine (PRME) EBT Margin (2024 - 2026)
Prime Medicine posted quarterly EBT Margin of 5798.25% for Q1 2026, down 222947.0% year-on-year from N/an in Q1 2025, and down 2.24% on a QoQ basis from 5671.24% in Q4 2025.
Prime Medicine (PRME) has 3 years of EBT Margin data on file, last reported at 5798.25% in Q1 2026.
- For the quarter ending Q1 2026, EBT Margin fell 222947.0% year-over-year to 5798.25%; the trailing twelve-month figure through Mar 2026 stood at 5021.84% (up 23414.0% YoY), and the FY2025 full-year result was 4408.48%, up 215813.0% from the prior year.
- EBT Margin for Q1 2026 stood at 5798.25%, down from 5671.24% in the prior quarter.
- Across five years, EBT Margin topped out at 1936.6% in Q4 2024 and bottomed at 25128.23% in Q3 2024.
- The 3-year median for EBT Margin is 5193.96% (2025), against an average of 7356.61%.
- Peak annual rise in EBT Margin reached 2081541 bps in 2025, while the deepest fall reached 373464 bps in 2025.
- A 3-year view of EBT Margin shows it stood at 1936.6% in 2024, then slumped by 193 bps to 5671.24% in 2025, then slipped by 2 bps to 5798.25% in 2026.
- The last three EBT Margin figures came in at 5798.25% (Q1 2026), 5671.24% (Q4 2025), and 4312.82% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBT Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | - |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | -6.40% |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | - |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 41.95% |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 23.05% |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 18.99% |
| 10 | Prime Medicine | 601.24 Mn | 601.24 Mn | - | -5,798.25% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -5,798.25% |
| Dec 31, 2025 | -5,671.24% |
| Sep 30, 2025 | -4,312.82% |
| Jun 30, 2025 | -4,716.68% |
| Mar 31, 2025 | -3,568.78% |
| Dec 31, 2024 | -1,936.60% |
| Sep 30, 2024 | -25,128.23% |
| Mar 31, 2024 | -7,720.30% |