Prime Medicine (PRME) Research & Development (2021 - 2026)

Prime Medicine's (PRME) quarterly Research & Development came in at $34.1 million in Q1 2026, down 15.92% YoY from $40.6 million in Q1 2025, and down 1.74% on a QoQ basis from $34.7 million in Q4 2025.

Prime Medicine (PRME) Research & Development (2021 - 2026) Analysis & Trends

Prime Medicine (PRME) has 6 years of Research & Development data on file, last reported at $34.1 million in Q1 2026.

  • Quarterly Research & Development fell 15.92% year-over-year to $34.1 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $154.2 million (down 2.47% YoY) and the FY2025 annual result came in at $160.6 million, up 3.44% from the prior year.
  • Research & Development slipped to $34.1 million in Q1 2026, from $34.7 million in the prior quarter.
  • In the past five years, Research & Development ranged from a high of $44.0 million in Q3 2025 to a low of $13.7 million in Q1 2022.
  • A 5-year average of $34.4 million and a median of $34.7 million in 2025 frame the typical range for Research & Development.
  • The widest YoY moves for Research & Development: up 238.47% in 2022, down 45.05% in 2022.
  • Tracing PRME's Research & Development over 5 years: stood at $29.1 million in 2022, then jumped by 42.66% to $41.5 million in 2023, then dropped by 17.74% to $34.1 million in 2024, then increased by 1.77% to $34.7 million in 2025, then dropped by 1.74% to $34.1 million in 2026.
  • The last three Research & Development figures came in at $34.1 million (Q1 2026), $34.7 million (Q4 2025), and $44.0 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) R&D (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 993.80 Mn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 1.63 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 1.37 Bn
4 Revolution Medicines 43.64 Bn 43.64 Bn - 394.92 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 612.28 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 1,146.05
7 Royalty Pharma 33.72 Bn 35.84 Bn - 97.90 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 413.13 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn 210.03 Mn
10 Prime Medicine 558.48 Mn 558.48 Mn - 33.40 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 33.40 Mn
Mar 31, 2026 34.11 Mn
Dec 31, 2025 34.71 Mn
Sep 30, 2025 43.99 Mn
Jun 30, 2025 41.38 Mn
Mar 31, 2025 40.56 Mn
Dec 31, 2024 34.10 Mn
Sep 30, 2024 40.34 Mn
Jun 30, 2024 43.07 Mn
Mar 31, 2024 37.77 Mn
Dec 31, 2023 41.46 Mn
Sep 30, 2023 40.97 Mn
Jun 30, 2023 34.60 Mn
Mar 31, 2023 30.88 Mn
Dec 31, 2022 29.06 Mn
Sep 30, 2022 25.05 Mn
Jun 30, 2022 18.94 Mn
Mar 31, 2022 13.68 Mn
Dec 31, 2021 52.89 Mn
Sep 30, 2021 7.40 Mn