Prime Medicine (PRME) Research & Development (2021 - 2026)
Prime Medicine posted quarterly Research & Development of $34.1 million for Q1 2026, down 15.92% year-on-year from $40.6 million in Q1 2025, and down 1.74% on a QoQ basis from $34.7 million in Q4 2025.
Prime Medicine (PRME) has 6 years of Research & Development data on file, last reported at $34.1 million in Q1 2026.
- For the quarter ending Q1 2026, Research & Development fell 15.92% year-over-year to $34.1 million; the trailing twelve-month figure through Mar 2026 stood at $154.2 million (down 2.47% YoY), and the FY2025 full-year result was $160.6 million, up 3.44% from the prior year.
- Research & Development for Q1 2026 stood at $34.1 million, down from $34.7 million in the prior quarter.
- Across five years, Research & Development topped out at $44.0 million in Q3 2025 and bottomed at $13.7 million in Q1 2022.
- The 5-year median for Research & Development is $34.7 million (2025), against an average of $34.4 million.
- Peak annual rise in Research & Development reached 238.47% in 2022, while the deepest fall reached 45.05% in 2022.
- A 5-year view of Research & Development shows it stood at $29.1 million in 2022, then surged by 42.66% to $41.5 million in 2023, then declined by 17.74% to $34.1 million in 2024, then rose by 1.77% to $34.7 million in 2025, then declined by 1.74% to $34.1 million in 2026.
- The last three Research & Development figures came in at $34.1 million (Q1 2026), $34.7 million (Q4 2025), and $44.0 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | R&D (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | 626,092.00 |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | 4.32 Mn |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | -101.30 Mn |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | 1.46 Mn |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 961.60 Mn |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | -2.30 Mn |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 1.54 Bn |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 364.87 Mn |
| 10 | Prime Medicine | 601.24 Mn | 601.24 Mn | - | 34.11 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 34.11 Mn |
| Dec 31, 2025 | 34.71 Mn |
| Sep 30, 2025 | 43.99 Mn |
| Jun 30, 2025 | 41.38 Mn |
| Mar 31, 2025 | 40.56 Mn |
| Dec 31, 2024 | 34.10 Mn |
| Sep 30, 2024 | 40.34 Mn |
| Jun 30, 2024 | 43.07 Mn |
| Mar 31, 2024 | 37.77 Mn |
| Dec 31, 2023 | 41.46 Mn |
| Sep 30, 2023 | 40.97 Mn |
| Jun 30, 2023 | 34.60 Mn |
| Mar 31, 2023 | 30.88 Mn |
| Dec 31, 2022 | 29.06 Mn |
| Sep 30, 2022 | 25.05 Mn |
| Jun 30, 2022 | 18.94 Mn |
| Mar 31, 2022 | 13.68 Mn |
| Dec 31, 2021 | 52.89 Mn |
| Sep 30, 2021 | 7.40 Mn |