Prime Medicine (PRME) Research & Development (2021 - 2026)
Prime Medicine's Research & Development came in at $33.4 million for Q2 2026, down 19.3% from $41.38 million a year earlier and down 2.1% from the prior quarter.
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Analysis
Prime Medicine (PRME) Research & Development (2021 - 2026) Analysis & Trends
Over the trailing twelve months to Jun 30, 2026, Prime Medicine reported Research & Development of $146.2 million, down 6.5% year-over-year; for FY2025, it was $160.64 million, up 3.4% from FY2024.
- Research & Development has increased in each of the last four years, with a five-year compound annual growth rate of 122.0% (FY2020 to FY2025).
- Going back by year, Research & Development was $155.29 million in FY2024 (+5.0%), $147.91 million in FY2023 (+70.5%), $86.73 million in FY2022 (+22.9%) and $70.55 million in FY2021.
- The Q2 2026 figure represents the lowest quarterly Research & Development since Q1 2023.
- Year-over-year, Research & Development increased in three of the last eight quarters, with an average decline of 5.0%.
- The fastest year-over-year change in Research & Development over five years came in Q3 2022 (growth of 238.5%), and the weakest in Q4 2022 (a decline of 45.1%).
- Business Quant data shows PRME's Research & Development at $34.11 million (Q1 2026), $34.71 million (Q4 2025) and $43.99 million (Q3 2025) in the three quarters before Q2 2026.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | R&D (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 3.65 Bn |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 2.34 Bn |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | 9.74 Bn |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | -2.85 Bn |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | -4.05 Bn |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 1.87 Bn |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | 1.76 Bn |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 2.81 Bn |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 993.80 Mn |
| 10 | Prime Medicine | 520.52 Mn | 520.52 Mn | - | 33.40 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 33.40 Mn |
| Mar 31, 2026 | 34.11 Mn |
| Dec 31, 2025 | 34.71 Mn |
| Sep 30, 2025 | 43.99 Mn |
| Jun 30, 2025 | 41.38 Mn |
| Mar 31, 2025 | 40.56 Mn |
| Dec 31, 2024 | 34.10 Mn |
| Sep 30, 2024 | 40.34 Mn |
| Jun 30, 2024 | 43.07 Mn |
| Mar 31, 2024 | 37.77 Mn |
| Dec 31, 2023 | 41.46 Mn |
| Sep 30, 2023 | 40.97 Mn |
| Jun 30, 2023 | 34.60 Mn |
| Mar 31, 2023 | 30.88 Mn |
| Dec 31, 2022 | 29.06 Mn |
| Sep 30, 2022 | 25.05 Mn |
| Jun 30, 2022 | 18.94 Mn |
| Mar 31, 2022 | 13.68 Mn |
| Dec 31, 2021 | 52.89 Mn |
| Sep 30, 2021 | 7.40 Mn |
API Access
Prime Medicine Research & Development API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=research-and-development&ticker=PRME&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "research-and-development", "ticker": "PRME", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=research-and-development&ticker=PRME&period=max&api_key=YOUR_API_KEY");
const data = await res.json();