Prime Medicine (PRME) Research & Development (2021 - 2026)

Prime Medicine posted quarterly Research & Development of $34.1 million for Q1 2026, down 15.92% year-on-year from $40.6 million in Q1 2025, and down 1.74% on a QoQ basis from $34.7 million in Q4 2025.

Prime Medicine (PRME) has 6 years of Research & Development data on file, last reported at $34.1 million in Q1 2026.

  • For the quarter ending Q1 2026, Research & Development fell 15.92% year-over-year to $34.1 million; the trailing twelve-month figure through Mar 2026 stood at $154.2 million (down 2.47% YoY), and the FY2025 full-year result was $160.6 million, up 3.44% from the prior year.
  • Research & Development for Q1 2026 stood at $34.1 million, down from $34.7 million in the prior quarter.
  • Across five years, Research & Development topped out at $44.0 million in Q3 2025 and bottomed at $13.7 million in Q1 2022.
  • The 5-year median for Research & Development is $34.7 million (2025), against an average of $34.4 million.
  • Peak annual rise in Research & Development reached 238.47% in 2022, while the deepest fall reached 45.05% in 2022.
  • A 5-year view of Research & Development shows it stood at $29.1 million in 2022, then surged by 42.66% to $41.5 million in 2023, then declined by 17.74% to $34.1 million in 2024, then rose by 1.77% to $34.7 million in 2025, then declined by 1.74% to $34.1 million in 2026.
  • The last three Research & Development figures came in at $34.1 million (Q1 2026), $34.7 million (Q4 2025), and $44.0 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) R&D (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - 626,092.00
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - 4.32 Mn
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -101.30 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - 1.46 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 961.60 Mn
7 Evaxion A 62.56 Bn 62.54 Bn - -2.30 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 1.54 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 364.87 Mn
10 Prime Medicine 601.24 Mn 601.24 Mn - 34.11 Mn

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 34.11 Mn
Dec 31, 2025 34.71 Mn
Sep 30, 2025 43.99 Mn
Jun 30, 2025 41.38 Mn
Mar 31, 2025 40.56 Mn
Dec 31, 2024 34.10 Mn
Sep 30, 2024 40.34 Mn
Jun 30, 2024 43.07 Mn
Mar 31, 2024 37.77 Mn
Dec 31, 2023 41.46 Mn
Sep 30, 2023 40.97 Mn
Jun 30, 2023 34.60 Mn
Mar 31, 2023 30.88 Mn
Dec 31, 2022 29.06 Mn
Sep 30, 2022 25.05 Mn
Jun 30, 2022 18.94 Mn
Mar 31, 2022 13.68 Mn
Dec 31, 2021 52.89 Mn
Sep 30, 2021 7.40 Mn