Prime Medicine (PRME) Operating Expenses (2021 - 2026)

Prime Medicine (PRME) has 6 years of Operating Expenses data on file, last reported at $51.5 million in Q1 2026.

• For the quarter ending Q1 2026, Operating Expenses fell 4.34% year-over-year to $51.5 million; the trailing twelve-month figure through Mar 2026 stood at $210.6 million (changed 0.13% YoY), and the FY2025 full-year result was $213.0 million, up 3.67% from the prior year.
• Operating Expenses for Q1 2026 stood at $51.5 million, up from $49.4 million in the prior quarter.
• Across five years, Operating Expenses topped out at $68.0 million in Q4 2023 and bottomed at $19.9 million in Q1 2022.
• The 5-year median for Operating Expenses is $49.4 million (2025), against an average of $46.5 million.
• Peak annual rise in Operating Expenses reached 203.59% in 2022, while the deepest fall reached 35.6% in 2022.
• A 5-year view of Operating Expenses shows it stood at $38.7 million in 2022, then soared by 75.89% to $68.0 million in 2023, then sank by 31.8% to $46.4 million in 2024, then advanced by 6.55% to $49.4 million in 2025, then grew by 4.17% to $51.5 million in 2026.
• The last three Operating Expenses figures came in at $51.5 million (Q1 2026), $49.4 million (Q4 2025), and $55.2 million (Q3 2025), per Business Quant data.

Peer Comparison