Prime Medicine (PRME) Operating Expenses (2021 - 2026)
Prime Medicine's (PRME) quarterly Operating Expenses came in at $51.5 million in Q1 2026, down 4.34% YoY from $53.8 million in Q1 2025, and up 4.17% on a QoQ basis from $49.4 million in Q4 2025.
Prime Medicine (PRME) Operating Expenses (2021 - 2026) Analysis & Trends
Prime Medicine (PRME) has 6 years of Operating Expenses data on file, last reported at $51.5 million in Q1 2026.
- Quarterly Operating Expenses fell 4.34% year-over-year to $51.5 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $210.6 million (changed 0.13% YoY) and the FY2025 annual result came in at $213.0 million, up 3.67% from the prior year.
- Operating Expenses climbed to $51.5 million in Q1 2026, from $49.4 million in the prior quarter.
- In the past five years, Operating Expenses ranged from a high of $68.0 million in Q4 2023 to a low of $19.9 million in Q1 2022.
- A 5-year average of $46.5 million and a median of $49.4 million in 2025 frame the typical range for Operating Expenses.
- The widest YoY moves for Operating Expenses: up 203.59% in 2022, down 35.6% in 2022.
- Tracing PRME's Operating Expenses over 5 years: stood at $38.7 million in 2022, then surged by 75.89% to $68.0 million in 2023, then slumped by 31.8% to $46.4 million in 2024, then gained by 6.55% to $49.4 million in 2025, then climbed by 4.17% to $51.5 million in 2026.
- The last three Operating Expenses figures came in at $51.5 million (Q1 2026), $49.4 million (Q4 2025), and $55.2 million (Q3 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 2.09 Bn |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 3.00 Bn |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | 2.89 Bn |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | 505.13 Mn |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 1.21 Bn |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | 4,978.15 |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 541.02 Mn |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | 1.06 Bn |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | 427.03 Mn |
| 10 | Prime Medicine | 558.48 Mn | 558.48 Mn | - | 44.44 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | 44.44 Mn |
| Mar 31, 2026 | 51.51 Mn |
| Dec 31, 2025 | 49.45 Mn |
| Sep 30, 2025 | 55.20 Mn |
| Jun 30, 2025 | 54.49 Mn |
| Mar 31, 2025 | 53.85 Mn |
| Dec 31, 2024 | 46.41 Mn |
| Sep 30, 2024 | 54.44 Mn |
| Jun 30, 2024 | 55.67 Mn |
| Mar 31, 2024 | 48.93 Mn |
| Dec 31, 2023 | 68.04 Mn |
| Sep 30, 2023 | 51.46 Mn |
| Jun 30, 2023 | 45.26 Mn |
| Mar 31, 2023 | 40.03 Mn |
| Dec 31, 2022 | 38.69 Mn |
| Sep 30, 2022 | 31.66 Mn |
| Jun 30, 2022 | 26.31 Mn |
| Mar 31, 2022 | 19.90 Mn |
| Dec 31, 2021 | 60.08 Mn |
| Sep 30, 2021 | 10.43 Mn |