Prime Medicine PRME
NASDAQ PRME
$3.70 -0.01 (-0.27%)
As of: Sep 4, 2026 · 3:59 PM EDT

Prime Medicine (PRME) Enterprise Value (2022 - 2026)

Prime Medicine's (PRME) quarterly Enterprise Value came in at -$135.5 million in Q1 2026, down 41.45% YoY from -$231.4 million in Q1 2025, and up 23.74% on a QoQ basis from -$177.7 million in Q4 2025.

Analysis

Prime Medicine (PRME) Enterprise Value (2022 - 2026) Analysis & Trends

Prime Medicine (PRME) has 6 years of Enterprise Value data on file, last reported at -$135.5 million in Q1 2026.

  • Quarterly Enterprise Value fell 41.45% year-over-year to -$135.5 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$135.5 million (down 41.45% YoY) and the FY2025 annual result came in at -$177.7 million, up 4.2% from the prior year.
  • Enterprise Value advanced to -$135.5 million in Q1 2026, from -$177.7 million in the prior quarter.
  • In the past five years, Enterprise Value ranged from a high of -$47.0 million in Q4 2023 to a low of -$286.1 million in Q4 2022.
  • A 5-year average of -$132.7 million and a median of -$127.0 million in 2023 frame the typical range for Enterprise Value.
  • Annual changes were most pronounced in 2023 — Enterprise Value surged 83.56% — and 2024, when it plunged 294.41%.
  • Tracing PRME's Enterprise Value over 5 years: stood at -$286.1 million in 2022, then soared by 83.56% to -$47.0 million in 2023, then sank by 294.41% to -$185.5 million in 2024, then climbed by 4.2% to -$177.7 million in 2025, then climbed by 23.74% to -$135.5 million in 2026.
  • The last three Enterprise Value figures came in at -$135.5 million (Q1 2026), -$177.7 million (Q4 2025), and -$76.3 million (Q3 2025), per Business Quant data.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Vertex Pharmaceuticals 138.47 Bn 130.62 Bn 2.84 Bn
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn
3 Argenx Se 63.38 Bn 58.19 Bn 1.37 Bn
4 Moderna 58.09 Bn 52.95 Bn 52.00 Mn
5 Revolution Medicines 44.33 Bn 44.33 Bn -
6 BeOne Medicines 40.02 Bn 34.92 Bn 1.53 Bn
7 Alnylam Pharmaceuticals 35.57 Bn 32.27 Bn 992.69 Mn
8 Royalty Pharma 28.45 Bn 27.61 Bn -
9 Insmed 27.48 Bn 26.32 Bn 358.27 Mn
10 Prime Medicine 653.96 Mn 653.96 Mn -
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 571.85 Mn
Mar 31, 2026 493.04 Mn
Dec 31, 2025 338.51 Mn
Sep 30, 2025 790.49 Mn
Jun 30, 2025 233.86 Mn
Mar 31, 2025 120.67 Mn
Dec 31, 2024 195.55 Mn
Sep 30, 2024 336.97 Mn
Jun 30, 2024 458.78 Mn
Mar 31, 2024 636.04 Mn
Dec 31, 2023 746.55 Mn
Sep 30, 2023 767.97 Mn
Jun 30, 2023 1.22 Bn
Mar 31, 2023 952.52 Mn
Dec 31, 2022 343.61 Mn