Prime Medicine (PRME) Enterprise Value (2021 - 2026)

Prime Medicine (PRME) reported Enterprise Value of -$135.5 million for Q1 2026, up 3.45% on a YoY basis from -$131.0 million in Q1 2025, and up 23.74% quarter-over-quarter from -$177.7 million in Q4 2025.

Prime Medicine (PRME) Enterprise Value (2021 - 2026) Analysis & Trends

Prime Medicine has reported Enterprise Value for 6 years, with the latest figure at -$135.5 million in Q1 2026.

  • For the quarter ending Q1 2026, Enterprise Value rose 3.45% year-over-year to -$135.5 million; the trailing twelve-month figure through Mar 2026 stood at -$135.5 million (up 3.45% YoY), and the FY2025 full-year result was -$177.7 million, up 4.2% from the prior year.
  • Enterprise Value for Q1 2026 stood at -$135.5 million, up from -$177.7 million in the prior quarter.
  • The five-year high for Enterprise Value was -$48.8 million in Q3 2023, with the low at -$286.1 million in Q4 2022.
  • Historically, Enterprise Value has averaged -$151.8 million across 5 years, with a median of -$140.3 million in 2025.
  • The largest YoY upside for Enterprise Value was 70.04% in 2024 against a maximum downside of 151.94% in 2024.
  • Prime Medicine's Enterprise Value stood at -$286.1 million in 2022, then surged by 59.38% to -$116.2 million in 2023, then sank by 59.6% to -$185.5 million in 2024, then climbed by 4.2% to -$177.7 million in 2025, then climbed by 23.74% to -$135.5 million in 2026.
  • The last three Enterprise Value figures came in at -$135.5 million (Q1 2026), -$177.7 million (Q4 2025), and -$208.4 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -32.30 Mn
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -4.14 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -286.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -18.44 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -2.77 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -7.20 Mn
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn -7.25 Bn
9 Abivax 91.96 Bn 91.96 Bn - -584.73 Mn
10 Prime Medicine 572.02 Mn 572.02 Mn - -135.50 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -135.50 Mn
Dec 31, 2025 -177.68 Mn
Sep 30, 2025 -208.43 Mn
Jun 30, 2025 -57.21 Mn
Mar 31, 2025 -140.34 Mn
Dec 31, 2024 -185.47 Mn
Sep 30, 2024 -122.89 Mn
Jun 30, 2024 -60.29 Mn
Mar 31, 2024 -204.11 Mn
Dec 31, 2023 -116.21 Mn
Sep 30, 2023 -48.78 Mn
Jun 30, 2023 -201.22 Mn
Mar 31, 2023 -243.39 Mn
Dec 31, 2022 -286.09 Mn
Sep 30, 2022 -137.12 Mn
Jun 30, 2022 -92.24 Mn
Mar 31, 2022 -164.25 Mn
Dec 31, 2021 -117.74 Mn
Sep 30, 2021 -200.66 Mn