Prime Medicine (PRME) Enterprise Value (2022 - 2026)
Prime Medicine's (PRME) quarterly Enterprise Value came in at -$135.5 million in Q1 2026, down 41.45% YoY from -$231.4 million in Q1 2025, and up 23.74% on a QoQ basis from -$177.7 million in Q4 2025.
Analysis
Prime Medicine (PRME) Enterprise Value (2022 - 2026) Analysis & Trends
Prime Medicine (PRME) has 6 years of Enterprise Value data on file, last reported at -$135.5 million in Q1 2026.
- Quarterly Enterprise Value fell 41.45% year-over-year to -$135.5 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$135.5 million (down 41.45% YoY) and the FY2025 annual result came in at -$177.7 million, up 4.2% from the prior year.
- Enterprise Value advanced to -$135.5 million in Q1 2026, from -$177.7 million in the prior quarter.
- In the past five years, Enterprise Value ranged from a high of -$47.0 million in Q4 2023 to a low of -$286.1 million in Q4 2022.
- A 5-year average of -$132.7 million and a median of -$127.0 million in 2023 frame the typical range for Enterprise Value.
- Annual changes were most pronounced in 2023 — Enterprise Value surged 83.56% — and 2024, when it plunged 294.41%.
- Tracing PRME's Enterprise Value over 5 years: stood at -$286.1 million in 2022, then soared by 83.56% to -$47.0 million in 2023, then sank by 294.41% to -$185.5 million in 2024, then climbed by 4.2% to -$177.7 million in 2025, then climbed by 23.74% to -$135.5 million in 2026.
- The last three Enterprise Value figures came in at -$135.5 million (Q1 2026), -$177.7 million (Q4 2025), and -$76.3 million (Q3 2025), per Business Quant data.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.47 Bn | 130.62 Bn | 2.84 Bn |
| 2 | Regeneron Pharmaceuticals | 85.18 Bn | 77.19 Bn | 3.93 Bn |
| 3 | Argenx Se | 63.38 Bn | 58.19 Bn | 1.37 Bn |
| 4 | Moderna | 58.09 Bn | 52.95 Bn | 52.00 Mn |
| 5 | Revolution Medicines | 44.33 Bn | 44.33 Bn | - |
| 6 | BeOne Medicines | 40.02 Bn | 34.92 Bn | 1.53 Bn |
| 7 | Alnylam Pharmaceuticals | 35.57 Bn | 32.27 Bn | 992.69 Mn |
| 8 | Royalty Pharma | 28.45 Bn | 27.61 Bn | - |
| 9 | Insmed | 27.48 Bn | 26.32 Bn | 358.27 Mn |
| 10 | Prime Medicine | 653.96 Mn | 653.96 Mn | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 571.85 Mn |
| Mar 31, 2026 | 493.04 Mn |
| Dec 31, 2025 | 338.51 Mn |
| Sep 30, 2025 | 790.49 Mn |
| Jun 30, 2025 | 233.86 Mn |
| Mar 31, 2025 | 120.67 Mn |
| Dec 31, 2024 | 195.55 Mn |
| Sep 30, 2024 | 336.97 Mn |
| Jun 30, 2024 | 458.78 Mn |
| Mar 31, 2024 | 636.04 Mn |
| Dec 31, 2023 | 746.55 Mn |
| Sep 30, 2023 | 767.97 Mn |
| Jun 30, 2023 | 1.22 Bn |
| Mar 31, 2023 | 952.52 Mn |
| Dec 31, 2022 | 343.61 Mn |