Prime Medicine (PRME) Enterprise Value (2021 - 2025)

Prime Medicine filings provide 5 years of Enterprise Value readings, the most recent being -$177.7 million for Q4 2025.

  • On a quarterly basis, Enterprise Value rose 5.21% to -$177.7 million in Q4 2025 year-over-year; TTM through Dec 2025 was -$177.7 million, a 5.21% increase, with the full-year FY2025 number at -$177.7 million, up 5.21% from a year prior.
  • Enterprise Value hit -$177.7 million in Q4 2025 for Prime Medicine, up from -$208.4 million in the prior quarter.
  • In the past five years, Enterprise Value ranged from a high of -$48.8 million in Q3 2023 to a low of -$286.1 million in Q4 2022.
  • Median Enterprise Value over the past 5 years was -$167.4 million (2022), compared with a mean of -$156.1 million.
  • The widest YoY moves for Enterprise Value: up 70.04% in 2024, down 249.8% in 2024.
  • Prime Medicine's Enterprise Value stood at -$117.7 million in 2021, then plummeted by 142.99% to -$286.1 million in 2022, then skyrocketed by 59.38% to -$116.2 million in 2023, then plummeted by 61.29% to -$187.4 million in 2024, then rose by 5.21% to -$177.7 million in 2025.
  • The last three reported values for Enterprise Value were -$177.7 million (Q4 2025), -$208.4 million (Q3 2025), and -$98.3 million (Q2 2025) per Business Quant data.