Growth Metrics

Spero Therapeutics (SPRO) Other Gross PP&E Adjustments (2016 - 2026)

Spero Therapeutics posted quarterly Other Gross PP&E Adjustments of -$2.2 million for Q1 2026, up 41.5% year-on-year from -$1.5 million in Q1 2025, and down 1.41% on a QoQ basis from -$2.1 million in Q4 2025.

Spero Therapeutics (SPRO) has 11 years of Other Gross PP&E Adjustments data on file, last reported at -$2.2 million in Q1 2026.

  • For the quarter ending Q1 2026, Other Gross PP&E Adjustments rose 41.5% year-over-year to -$2.2 million; the trailing twelve-month figure through Mar 2026 stood at -$2.2 million (up 41.5% YoY), and the FY2025 full-year result was -$2.1 million, down 25.46% from the prior year.
  • Other Gross PP&E Adjustments for Q1 2026 stood at -$2.2 million, down from -$2.1 million in the prior quarter.
  • Across five years, Other Gross PP&E Adjustments topped out at -$1.2 million in Q4 2023 and bottomed at -$7.8 million in Q1 2022.
  • The 5-year median for Other Gross PP&E Adjustments is -$4.0 million (2024), against an average of -$4.1 million.
  • The widest annual swing landed in 2024, when Other Gross PP&E Adjustments slumped 36.2%; it then soared 47.48% in 2025.
  • A 5-year view of Other Gross PP&E Adjustments shows it stood at -$2.2 million in 2022, then soared by 43.5% to -$1.2 million in 2023, then slumped by 36.2% to -$1.7 million in 2024, then slipped by 25.46% to -$2.1 million in 2025, then decreased by 1.41% to -$2.2 million in 2026.
  • The last three Other Gross PP&E Adjustments figures came in at -$2.2 million (Q1 2026), -$2.1 million (Q4 2025), and -$2.1 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Other Gross PP&E Adjustments (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -83,048.00
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -60,691.22
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -285.20 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -892,000.00
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn -1.69 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn -
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn -189.30 Mn
10 Spero Therapeutics 162.39 Mn 106.26 Mn - -2.15 Mn

Historic Data

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DateValue
Mar 31, 2026 -2.15 Mn
Mar 31, 2026 -2.15 Mn
Dec 31, 2025 -2.12 Mn
Dec 31, 2025 -2.12 Mn
Sep 30, 2025 -2.10 Mn
Sep 30, 2025 -2.10 Mn
Jun 30, 2025 -3.49 Mn
Jun 30, 2025 -3.49 Mn
Mar 31, 2025 -3.68 Mn
Mar 31, 2025 -3.68 Mn
Dec 31, 2024 -1.69 Mn
Dec 31, 2024 -1.69 Mn
Sep 30, 2024 -4.00 Mn
Sep 30, 2024 -4.00 Mn
Jun 30, 2024 -4.46 Mn
Jun 30, 2024 -4.46 Mn
Mar 31, 2024 -4.78 Mn
Mar 31, 2024 -4.78 Mn
Dec 31, 2023 -1.24 Mn
Dec 31, 2023 -1.24 Mn
Sep 30, 2023 -5.50 Mn
Sep 30, 2023 -5.50 Mn
Jun 30, 2023 -5.71 Mn
Jun 30, 2023 -5.71 Mn
Mar 31, 2023 -6.06 Mn
Mar 31, 2023 -6.06 Mn
Dec 31, 2022 -2.20 Mn
Dec 31, 2022 -2.20 Mn
Sep 30, 2022 -6.19 Mn
Sep 30, 2022 -6.19 Mn
Jun 30, 2022 -6.75 Mn
Jun 30, 2022 -6.75 Mn
Mar 31, 2022 -7.76 Mn
Mar 31, 2022 -7.76 Mn
Dec 31, 2021 -3.53 Mn
Dec 31, 2021 -3.53 Mn
Sep 30, 2021 -8.11 Mn
Sep 30, 2021 -8.11 Mn
Jun 30, 2021 -8.27 Mn
Jun 30, 2021 -8.27 Mn
Mar 31, 2021 -8.47 Mn
Mar 31, 2021 -8.47 Mn
Dec 31, 2020 -4.24 Mn
Dec 31, 2020 -4.24 Mn
Sep 30, 2020 -8.60 Mn
Sep 30, 2020 -8.60 Mn
Jun 30, 2020 -5.78 Mn
Jun 30, 2020 -5.78 Mn
Mar 31, 2020 -5.44 Mn
Mar 31, 2020 -5.44 Mn
Dec 31, 2019 -1.89 Mn
Dec 31, 2019 -1.89 Mn
Sep 30, 2019 -4.58 Mn
Sep 30, 2019 -4.58 Mn
Jun 30, 2019 -4.82 Mn
Jun 30, 2019 -4.82 Mn
Mar 31, 2019 -4.84 Mn
Mar 31, 2019 -4.84 Mn
Dec 31, 2018 2.80 Mn
Dec 31, 2018 2.80 Mn
Sep 30, 2018 -727,000.00
Sep 30, 2018 -727,000.00
Jun 30, 2018 -869,000.00
Jun 30, 2018 -869,000.00
Mar 31, 2018 -824,000.00
Mar 31, 2018 -824,000.00
Dec 31, 2017 929,000.00
Dec 31, 2017 929,000.00
Sep 30, 2017 -1.64 Mn
Sep 30, 2017 -1.64 Mn
Dec 31, 2016 728,000.00
Dec 31, 2016 728,000.00