Spero Therapeutics (SPRO) EBIT (2016 - 2026)
Spero Therapeutics' (SPRO) quarterly EBIT came in at -$9.9 million in Q2 2026, down 306.14% on a YoY basis from $4.8 million in Q2 2025, and down 31.68% quarter-over-quarter from -$7.5 million in Q1 2026.
Analysis
Spero Therapeutics (SPRO) EBIT (2016 - 2026) Analysis & Trends
Spero Therapeutics (SPRO) has reported EBIT for 11 consecutive years, with -$9.9 million the latest figure, recorded in Q2 2026.
- For the quarter ending Q2 2026, EBIT fell 306.14% year-over-year to -$9.9 million; the trailing twelve-month figure through Jun 2026 stood at $6.0 million (up 110.48% YoY), and the FY2025 full-year result was $6.3 million, up 108.61% from the prior year.
- EBIT declined to -$9.9 million in Q2 2026 per SPRO's latest filing, from -$7.5 million in the prior quarter.
- Across five years, EBIT topped out at $50.5 million in Q4 2023 and bottomed at -$30.2 million in Q1 2022.
- Historically, EBIT has averaged -$5.8 million across 5 years, with a median of -$12.4 million in 2022.
- The sharpest annual moves came in 2024 and 2025: EBIT slumped 861.38% in 2024, then soared 244.56% in 2025.
- Over 5 years, EBIT stood at $25.9 million in 2022, then soared by 94.92% to $50.5 million in 2023, then slumped by 142.99% to -$21.7 million in 2024, then jumped by 244.56% to $31.4 million in 2025, then plunged by 131.61% to -$9.9 million in 2026.
- According to Business Quant data, EBIT over the past three periods registered -$9.9 million, -$7.5 million, and $31.4 million for Q2 2026, Q1 2026, and Q4 2025 respectively.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBIT (Qtr) |
|---|---|---|---|---|---|
| 1 | Amgen | 211.73 Bn | 197.74 Bn | 7.24 Bn | 3.51 Bn |
| 2 | Gilead Sciences | 180.92 Bn | 177.74 Bn | 6.22 Bn | -10.39 Bn |
| 3 | Vertex Pharmaceuticals | 132.16 Bn | 124.30 Bn | 2.84 Bn | 1.25 Bn |
| 4 | Regeneron Pharmaceuticals | 82.89 Bn | 74.90 Bn | 3.93 Bn | 1.29 Bn |
| 5 | Argenx Se | 61.41 Bn | 56.23 Bn | 1.37 Bn | 493.00 Mn |
| 6 | Moderna | 53.99 Bn | 48.85 Bn | 52.00 Mn | -815.00 Mn |
| 7 | Alnylam Pharmaceuticals | 34.48 Bn | 31.18 Bn | 992.69 Mn | 231.44 Mn |
| 8 | Biogen | 31.15 Bn | 29.86 Bn | 1.96 Bn | -644.50 Mn |
| 9 | Roivant Sciences | 30.05 Bn | 30.05 Bn | 1.16 Mn | -365.99 Mn |
| 10 | Spero Therapeutics | 67.82 Mn | 17.05 Mn | - | -9.93 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -9.93 Mn |
| Mar 31, 2026 | -7.54 Mn |
| Dec 31, 2025 | 31.41 Mn |
| Sep 30, 2025 | -7.92 Mn |
| Jun 30, 2025 | -2.44 Mn |
| Mar 31, 2025 | -14.73 Mn |
| Dec 31, 2024 | -21.73 Mn |
| Sep 30, 2024 | -18.59 Mn |
| Jun 30, 2024 | -19.06 Mn |
| Mar 31, 2024 | -13.98 Mn |
| Dec 31, 2023 | 50.53 Mn |
| Sep 30, 2023 | -1.93 Mn |
| Jun 30, 2023 | -12.89 Mn |
| Mar 31, 2023 | -14.23 Mn |
| Dec 31, 2022 | 25.92 Mn |
| Sep 30, 2022 | -11.83 Mn |
| Jun 30, 2022 | -26.08 Mn |
| Mar 31, 2022 | -30.21 Mn |
| Dec 31, 2021 | -27.50 Mn |
| Sep 30, 2021 | -22.52 Mn |