Spero Therapeutics SPRO
NASDAQ SPRO
$1.17 -0.02 (-1.68%)
At close: Sep 9, 2026 · 4:00 PM EDT

Spero Therapeutics (SPRO) EBIT (2016 - 2026)

Spero Therapeutics' (SPRO) quarterly EBIT came in at -$9.9 million in Q2 2026, down 306.14% on a YoY basis from $4.8 million in Q2 2025, and down 31.68% quarter-over-quarter from -$7.5 million in Q1 2026.

Analysis

Spero Therapeutics (SPRO) EBIT (2016 - 2026) Analysis & Trends

Spero Therapeutics (SPRO) has reported EBIT for 11 consecutive years, with -$9.9 million the latest figure, recorded in Q2 2026.

  • For the quarter ending Q2 2026, EBIT fell 306.14% year-over-year to -$9.9 million; the trailing twelve-month figure through Jun 2026 stood at $6.0 million (up 110.48% YoY), and the FY2025 full-year result was $6.3 million, up 108.61% from the prior year.
  • EBIT declined to -$9.9 million in Q2 2026 per SPRO's latest filing, from -$7.5 million in the prior quarter.
  • Across five years, EBIT topped out at $50.5 million in Q4 2023 and bottomed at -$30.2 million in Q1 2022.
  • Historically, EBIT has averaged -$5.8 million across 5 years, with a median of -$12.4 million in 2022.
  • The sharpest annual moves came in 2024 and 2025: EBIT slumped 861.38% in 2024, then soared 244.56% in 2025.
  • Over 5 years, EBIT stood at $25.9 million in 2022, then soared by 94.92% to $50.5 million in 2023, then slumped by 142.99% to -$21.7 million in 2024, then jumped by 244.56% to $31.4 million in 2025, then plunged by 131.61% to -$9.9 million in 2026.
  • According to Business Quant data, EBIT over the past three periods registered -$9.9 million, -$7.5 million, and $31.4 million for Q2 2026, Q1 2026, and Q4 2025 respectively.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIT (Qtr)
1 Amgen 211.73 Bn 197.74 Bn 7.24 Bn 3.51 Bn
2 Gilead Sciences 180.92 Bn 177.74 Bn 6.22 Bn -10.39 Bn
3 Vertex Pharmaceuticals 132.16 Bn 124.30 Bn 2.84 Bn 1.25 Bn
4 Regeneron Pharmaceuticals 82.89 Bn 74.90 Bn 3.93 Bn 1.29 Bn
5 Argenx Se 61.41 Bn 56.23 Bn 1.37 Bn 493.00 Mn
6 Moderna 53.99 Bn 48.85 Bn 52.00 Mn -815.00 Mn
7 Alnylam Pharmaceuticals 34.48 Bn 31.18 Bn 992.69 Mn 231.44 Mn
8 Biogen 31.15 Bn 29.86 Bn 1.96 Bn -644.50 Mn
9 Roivant Sciences 30.05 Bn 30.05 Bn 1.16 Mn -365.99 Mn
10 Spero Therapeutics 67.82 Mn 17.05 Mn - -9.93 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -9.93 Mn
Mar 31, 2026 -7.54 Mn
Dec 31, 2025 31.41 Mn
Sep 30, 2025 -7.92 Mn
Jun 30, 2025 -2.44 Mn
Mar 31, 2025 -14.73 Mn
Dec 31, 2024 -21.73 Mn
Sep 30, 2024 -18.59 Mn
Jun 30, 2024 -19.06 Mn
Mar 31, 2024 -13.98 Mn
Dec 31, 2023 50.53 Mn
Sep 30, 2023 -1.93 Mn
Jun 30, 2023 -12.89 Mn
Mar 31, 2023 -14.23 Mn
Dec 31, 2022 25.92 Mn
Sep 30, 2022 -11.83 Mn
Jun 30, 2022 -26.08 Mn
Mar 31, 2022 -30.21 Mn
Dec 31, 2021 -27.50 Mn
Sep 30, 2021 -22.52 Mn