Spero Therapeutics (SPRO) EBIT (2016 - 2026)
Spero Therapeutics (SPRO) reported EBIT of -$7.5 million for Q1 2026, up 48.83% on a YoY basis from -$5.1 million in Q1 2025, and down 124.0% quarter-over-quarter from $31.4 million in Q4 2025.
Spero Therapeutics (SPRO) EBIT (2016 - 2026) Analysis & Trends
Spero Therapeutics has reported EBIT for 11 years, with the latest figure at -$7.5 million in Q1 2026.
- For the quarter ending Q1 2026, EBIT rose 48.83% year-over-year to -$7.5 million; the trailing twelve-month figure through Mar 2026 stood at $13.5 million (up 117.37% YoY), and the FY2025 full-year result was $6.3 million, up 108.61% from the prior year.
- EBIT for Q1 2026 stood at -$7.5 million, down from $31.4 million in the prior quarter.
- The five-year high for EBIT was $54.5 million in Q4 2023, with the low at -$30.2 million in Q1 2022.
- Historically, EBIT has averaged -$5.5 million across 5 years, with a median of -$12.9 million in 2023.
- Annual changes were most pronounced in 2024 — EBIT sank 861.38% — and 2025, when it jumped 223.68%.
- Spero Therapeutics' EBIT stood at $26.8 million in 2022, then jumped by 103.41% to $54.5 million in 2023, then slumped by 146.63% to -$25.4 million in 2024, then jumped by 223.68% to $31.4 million in 2025, then slumped by 124.0% to -$7.5 million in 2026.
- The last three EBIT figures came in at -$7.5 million (Q1 2026), $31.4 million (Q4 2025), and -$7.9 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBIT (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | -32.68 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -2.97 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.82 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -15.76 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | -1.51 Mn |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -65.83 Mn |
| 10 | Spero Therapeutics | 129.74 Mn | 73.61 Mn | - | -7.54 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -7.54 Mn |
| Dec 31, 2025 | 31.41 Mn |
| Sep 30, 2025 | -7.92 Mn |
| Jun 30, 2025 | -2.44 Mn |
| Mar 31, 2025 | -14.73 Mn |
| Dec 31, 2024 | -25.39 Mn |
| Sep 30, 2024 | -18.59 Mn |
| Jun 30, 2024 | -19.06 Mn |
| Mar 31, 2024 | -13.98 Mn |
| Dec 31, 2023 | 54.46 Mn |
| Sep 30, 2023 | -1.93 Mn |
| Jun 30, 2023 | -12.89 Mn |
| Mar 31, 2023 | -14.23 Mn |
| Dec 31, 2022 | 26.77 Mn |
| Sep 30, 2022 | -11.68 Mn |
| Jun 30, 2022 | -26.08 Mn |
| Mar 31, 2022 | -30.21 Mn |
| Dec 31, 2021 | -27.50 Mn |
| Sep 30, 2021 | -22.52 Mn |
| Jun 30, 2021 | -18.54 Mn |