Spero Therapeutics (SPRO) Total Debt (2019 - 2026)

Spero Therapeutics' (SPRO) quarterly Total Debt came in at $91000.0 in Q1 2026, little changed on a QoQ basis from $91000.0 in Q4 2025.

Spero Therapeutics (SPRO) Total Debt (2019 - 2026) Analysis & Trends

Spero Therapeutics (SPRO) has 8 years of Total Debt data on file, last reported at $91000.0 in Q1 2026.

Quarterly Total Debt changed N/A year-over-year to $91000.0 in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $91000.0 (changed N/A YoY) and the FY2025 annual result came in at $91000.0, changed N/A from the prior year.
Total Debt held at $91000.0 in Q1 2026, from $91000.0 in the prior quarter.
In the past five years, Total Debt ranged from a high of $128000.0 in Q1 2022 to a low of $13000.0 in Q3 2024.
A 5-year average of $77846.2 and a median of $87000.0 in 2023 frame the typical range for Total Debt.
Annual changes were most pronounced in 2023 — Total Debt fell 9.38% — and 2024, when it tumbled 79.03%.
Tracing SPRO's Total Debt over 5 years: stood at $96000.0 in 2022, then slipped by 9.38% to $87000.0 in 2023, then plunged by 85.06% to $13000.0 in 2024, then surged by 600.0% to $91000.0 in 2025, then changed by 0.0% to $91000.0 in 2026.
The last three Total Debt figures came in at $91000.0 (Q1 2026), $91000.0 (Q4 2025), and $13000.0 (Q3 2024), per Business Quant data.

#	Company	Market Cap	Enterprise Value	Gross Profit (Qtr)	Total Debt (Qtr)
1	Vertex Pharmaceuticals	137.11 Bn	129.26 Bn	2.84 Bn	-
2	Regeneron Pharmaceuticals	84.98 Bn	76.99 Bn	3.93 Bn	1.99 Bn
3	Argenx Se	64.52 Bn	59.33 Bn	1.37 Bn	-
4	Moderna	53.23 Bn	48.09 Bn	52.00 Mn	591.00 Mn
5	BeOne Medicines	41.23 Bn	36.14 Bn	1.53 Bn	1.07 Bn
6	Alnylam Pharmaceuticals	30.65 Bn	27.34 Bn	992.69 Mn	-
7	Insmed	27.15 Bn	25.99 Bn	358.27 Mn	546.77 Mn
8	Royalty Pharma	26.98 Bn	26.14 Bn	-	9.34 Bn
9	BioNTech SE	26.78 Bn	8.39 Bn	668.28 Mn	770.36 Mn
10	Spero Therapeutics	70.14 Mn	19.37 Mn	-	91,000.00

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