Growth Metrics

Spero Therapeutics (SPRO) FCF Margin (2016 - 2025)

Historic FCF Margin for Spero Therapeutics (SPRO) over the last 10 years, with Q3 2025 value amounting to 320.14%.

  • Spero Therapeutics' FCF Margin rose 2253800.0% to 320.14% in Q3 2025 from the same period last year, while for Sep 2025 it was 68.25%, marking a year-over-year decrease of 517800.0%. This contributed to the annual value of 48.87% for FY2024, which is 170700.0% down from last year.
  • Per Spero Therapeutics' latest filing, its FCF Margin stood at 320.14% for Q3 2025, which was up 2253800.0% from 124.7% recorded in Q2 2025.
  • In the past 5 years, Spero Therapeutics' FCF Margin registered a high of 343.97% during Q4 2022, and its lowest value of 1364.09% during Q1 2022.
  • Moreover, its 5-year median value for FCF Margin was 155.55% (2024), whereas its average is 275.45%.
  • Within the past 5 years, the most significant YoY rise in Spero Therapeutics' FCF Margin was 13392300bps (2022), while the steepest drop was -11520500bps (2022).
  • Over the past 5 years, Spero Therapeutics' FCF Margin (Quarter) stood at 995.26% in 2021, then surged by 135bps to 343.97% in 2022, then tumbled by -107bps to 23.79% in 2023, then tumbled by -554bps to 155.55% in 2024, then surged by 306bps to 320.14% in 2025.
  • Its FCF Margin was 320.14% in Q3 2025, compared to 124.7% in Q2 2025 and 68.13% in Q1 2025.