Spero Therapeutics (SPRO) EV to EBIT (2017 - 2026)
Spero Therapeutics' (SPRO) quarterly EV to EBIT came in at 7.83 in Q2 2026, up 85.47% on a YoY basis from 4.22 in Q2 2025, and up 25.6% quarter-over-quarter from 10.52 in Q1 2026.
Analysis
Spero Therapeutics (SPRO) EV to EBIT (2017 - 2026) Analysis & Trends
Spero Therapeutics (SPRO) has reported EV to EBIT for 10 consecutive years, with 7.83 the latest figure, recorded in Q2 2026.
- For the quarter ending Q2 2026, EV to EBIT rose 85.47% year-over-year to 7.83; the trailing twelve-month figure through Jun 2026 stood at 12.9 (up 662.99% YoY), and the FY2025 full-year result was 14.44, up 31796.86% from the prior year.
- EV to EBIT climbed to 7.83 in Q2 2026 per SPRO's latest filing, from 10.52 in the prior quarter.
- Across five years, EV to EBIT topped out at 15.35 in Q3 2023 and bottomed at 53.91 in Q2 2025.
- Historically, EV to EBIT has averaged 3.86 across 5 years, with a median of 0.25 in 2024.
- The widest YoY moves for EV to EBIT: up 1987.19% in 2025, down 15270.89% in 2025.
- Over 5 years, EV to EBIT stood at 1.7 in 2022, then soared by 101.83% to 0.03 in 2023, then tumbled by 593.12% to 0.15 in 2024, then surged by 1987.19% to 2.9 in 2025, then tumbled by 369.72% to 7.83 in 2026.
- According to Business Quant data, EV to EBIT over the past three periods registered 7.83, 10.52, and 2.9 for Q2 2026, Q1 2026, and Q4 2025 respectively.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Amgen | 211.73 Bn | 197.74 Bn | 7.24 Bn |
| 2 | Gilead Sciences | 180.92 Bn | 177.74 Bn | 6.22 Bn |
| 3 | Vertex Pharmaceuticals | 132.16 Bn | 124.30 Bn | 2.84 Bn |
| 4 | Regeneron Pharmaceuticals | 82.89 Bn | 74.90 Bn | 3.93 Bn |
| 5 | Argenx Se | 61.41 Bn | 56.23 Bn | 1.37 Bn |
| 6 | Moderna | 53.99 Bn | 48.85 Bn | 52.00 Mn |
| 7 | Alnylam Pharmaceuticals | 34.48 Bn | 31.18 Bn | 992.69 Mn |
| 8 | Biogen | 31.15 Bn | 29.86 Bn | 1.96 Bn |
| 9 | Roivant Sciences | 30.05 Bn | 30.05 Bn | 1.16 Mn |
| 10 | Spero Therapeutics | 67.82 Mn | 17.05 Mn | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -7.83 |
| Mar 31, 2026 | -10.52 |
| Dec 31, 2025 | 2.90 |
| Sep 30, 2025 | -7.23 |
| Jun 30, 2025 | -53.91 |
| Mar 31, 2025 | 0.59 |
| Dec 31, 2024 | -0.15 |
| Sep 30, 2024 | 0.19 |
| Jun 30, 2024 | -0.35 |
| Mar 31, 2024 | -0.74 |
| Dec 31, 2023 | 0.03 |
| Sep 30, 2023 | 15.35 |
| Jun 30, 2023 | 0.11 |
| Mar 31, 2023 | 1.41 |
| Dec 31, 2022 | -1.70 |
| Sep 30, 2022 | -2.98 |
| Jun 30, 2022 | 0.74 |
| Mar 31, 2022 | -5.40 |
| Dec 31, 2021 | -13.53 |
| Sep 30, 2021 | -20.86 |