Spero Therapeutics (SPRO) Invested Capital (2016 - 2026)
Spero Therapeutics posted quarterly Invested Capital of $52.9 million for Q1 2026, up 56.54% year-on-year from $33.8 million in Q1 2025, and down 10.31% on a QoQ basis from $59.0 million in Q4 2025.
Spero Therapeutics (SPRO) has 11 years of Invested Capital data on file, last reported at $52.9 million in Q1 2026.
- For the quarter ending Q1 2026, Invested Capital rose 56.54% year-over-year to $52.9 million; the trailing twelve-month figure through Mar 2026 stood at $52.9 million (up 56.54% YoY), and the FY2025 full-year result was $59.0 million, up 27.96% from the prior year.
- Invested Capital for Q1 2026 stood at $52.9 million, down from $59.0 million in the prior quarter.
- Across five years, Invested Capital topped out at $106.9 million in Q4 2023 and bottomed at $26.5 million in Q3 2025.
- The 5-year median for Invested Capital is $54.8 million (2023), against an average of $57.8 million.
- The widest annual swing landed in 2022, when Invested Capital sank 70.84%; it then soared 64.61% in 2023.
- A 5-year view of Invested Capital shows it stood at $75.9 million in 2022, then jumped by 40.77% to $106.9 million in 2023, then slumped by 56.85% to $46.1 million in 2024, then gained by 27.96% to $59.0 million in 2025, then declined by 10.31% to $52.9 million in 2026.
- The last three Invested Capital figures came in at $52.9 million (Q1 2026), $59.0 million (Q4 2025), and $26.5 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Invested Cap. (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | 595,226.00 |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | - |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | 110.96 Mn |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | 14.38 Mn |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 19.36 Bn |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 31.42 Bn |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 1.08 Bn |
| 10 | Spero Therapeutics | 162.39 Mn | 106.26 Mn | - | 52.93 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 52.93 Mn |
| Dec 31, 2025 | 59.02 Mn |
| Sep 30, 2025 | 26.49 Mn |
| Jun 30, 2025 | 32.83 Mn |
| Mar 31, 2025 | 33.81 Mn |
| Dec 31, 2024 | 46.12 Mn |
| Sep 30, 2024 | 65.51 Mn |
| Jun 30, 2024 | 80.50 Mn |
| Mar 31, 2024 | 96.25 Mn |
| Dec 31, 2023 | 106.89 Mn |
| Sep 30, 2023 | 53.71 Mn |
| Jun 30, 2023 | 54.78 Mn |
| Mar 31, 2023 | 64.84 Mn |
| Dec 31, 2022 | 75.93 Mn |
| Sep 30, 2022 | 32.63 Mn |
| Jun 30, 2022 | 36.04 Mn |
| Mar 31, 2022 | 63.47 Mn |
| Dec 31, 2021 | 88.29 Mn |
| Sep 30, 2021 | 111.90 Mn |
| Jun 30, 2021 | 90.25 Mn |
| Mar 31, 2021 | 118.85 Mn |
| Dec 31, 2020 | 132.04 Mn |
| Sep 30, 2020 | 132.79 Mn |
| Jun 30, 2020 | 73.71 Mn |
| Mar 31, 2020 | 82.43 Mn |
| Dec 31, 2019 | 74.57 Mn |
| Sep 30, 2019 | 93.26 Mn |
| Jun 30, 2019 | 109.89 Mn |
| Mar 31, 2019 | 113.55 Mn |
| Dec 31, 2018 | 116.08 Mn |
| Sep 30, 2018 | 125.78 Mn |
| Jun 30, 2018 | 65.89 Mn |
| Mar 31, 2018 | 75.12 Mn |
| Dec 31, 2017 | 85.18 Mn |
| Sep 30, 2017 | -81.62 Mn |
| Dec 31, 2016 | -46.54 Mn |