Spero Therapeutics SPRO
NASDAQ SPRO
$1.17 -0.02 (-1.68%)
At close: Sep 9, 2026 · 4:00 PM EDT

Spero Therapeutics (SPRO) EBT (2016 - 2026)

Spero Therapeutics' (SPRO) quarterly EBT came in at -$9.5 million in Q2 2026, down 460.39% on a YoY basis from $2.6 million in Q2 2025, and down 32.59% quarter-over-quarter from -$7.2 million in Q1 2026.

Analysis

Spero Therapeutics (SPRO) EBT (2016 - 2026) Analysis & Trends

Spero Therapeutics (SPRO) has reported EBT for 11 consecutive years, with -$9.5 million the latest figure, recorded in Q2 2026.

  • For the quarter ending Q2 2026, EBT fell 460.39% year-over-year to -$9.5 million; the trailing twelve-month figure through Jun 2026 stood at $7.6 million (up 114.27% YoY), and the FY2025 full-year result was $8.8 million, up 112.88% from the prior year.
  • EBT slipped to -$9.5 million in Q2 2026 per SPRO's latest filing, from -$7.2 million in the prior quarter.
  • Across five years, EBT topped out at $51.6 million in Q4 2023 and bottomed at -$30.1 million in Q1 2022.
  • Historically, EBT has averaged -$5.1 million across 5 years, with a median of -$11.8 million in 2022.
  • The sharpest annual moves came in 2024 and 2025: EBT tumbled 1654.23% in 2024, then soared 254.29% in 2025.
  • Over 5 years, EBT stood at $26.8 million in 2022, then soared by 92.66% to $51.6 million in 2023, then plunged by 139.94% to -$20.6 million in 2024, then jumped by 254.29% to $31.8 million in 2025, then slumped by 130.05% to -$9.5 million in 2026.
  • According to Business Quant data, EBT over the past three periods registered -$9.5 million, -$7.2 million, and $31.8 million for Q2 2026, Q1 2026, and Q4 2025 respectively.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT (Qtr)
1 Amgen 211.73 Bn 197.74 Bn 7.24 Bn 2.77 Bn
2 Gilead Sciences 180.92 Bn 177.74 Bn 6.22 Bn -10.25 Bn
3 Vertex Pharmaceuticals 132.16 Bn 124.30 Bn 2.84 Bn 1.39 Bn
4 Regeneron Pharmaceuticals 82.89 Bn 74.90 Bn 3.93 Bn 1.53 Bn
5 Argenx Se 61.41 Bn 56.23 Bn 1.37 Bn 542.00 Mn
6 Moderna 53.99 Bn 48.85 Bn 52.00 Mn -767.00 Mn
7 Alnylam Pharmaceuticals 34.48 Bn 31.18 Bn 992.69 Mn 177.81 Mn
8 Biogen 31.15 Bn 29.86 Bn 1.96 Bn 132.40 Mn
9 Roivant Sciences 30.05 Bn 30.05 Bn 1.16 Mn -294.56 Mn
10 Spero Therapeutics 67.82 Mn 17.05 Mn - -9.55 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -9.55 Mn
Mar 31, 2026 -7.20 Mn
Dec 31, 2025 31.78 Mn
Sep 30, 2025 -7.38 Mn
Jun 30, 2025 -1.70 Mn
Mar 31, 2025 -13.87 Mn
Dec 31, 2024 -20.60 Mn
Sep 30, 2024 -17.44 Mn
Jun 30, 2024 -17.86 Mn
Mar 31, 2024 -12.66 Mn
Dec 31, 2023 51.58 Mn
Sep 30, 2023 -994,000.00
Jun 30, 2023 -11.91 Mn
Mar 31, 2023 -13.26 Mn
Dec 31, 2022 26.77 Mn
Sep 30, 2022 -11.68 Mn
Jun 30, 2022 -25.97 Mn
Mar 31, 2022 -30.14 Mn
Dec 31, 2021 -27.43 Mn
Sep 30, 2021 -22.43 Mn