Spero Therapeutics (SPRO) EBT (2016 - 2026)
Spero Therapeutics' (SPRO) quarterly EBT came in at -$7.4 million in Q1 2026, up 46.75% YoY from -$5.0 million in Q1 2025, and down 124.96% on a QoQ basis from $29.6 million in Q4 2025.
Spero Therapeutics (SPRO) EBT (2016 - 2026) Analysis & Trends
Spero Therapeutics (SPRO) has 11 years of EBT data on file, last reported at -$7.4 million in Q1 2026.
- Quarterly EBT rose 46.75% year-over-year to -$7.4 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$113.2 million (up 40.71% YoY) and the FY2025 annual result came in at $5.4 million, up 102.84% from the prior year.
- EBT slipped to -$7.4 million in Q1 2026, from $29.6 million in the prior quarter.
- In the past five years, EBT ranged from a high of $29.6 million in Q4 2025 to a low of -$143.0 million in Q4 2024.
- A 5-year average of -$33.3 million and a median of -$16.3 million in 2024 frame the typical range for EBT.
- Annual changes were most pronounced in 2024 — EBT sank 1550.36% — and 2025, when it surged 120.69%.
- Tracing SPRO's EBT over 5 years: stood at -$92.4 million in 2022, then soared by 35.93% to -$59.2 million in 2023, then sank by 141.56% to -$143.0 million in 2024, then surged by 120.69% to $29.6 million in 2025, then tumbled by 124.96% to -$7.4 million in 2026.
- The last three EBT figures came in at -$7.4 million (Q1 2026), $29.6 million (Q4 2025), and -$27.7 million (Q3 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBT (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 137.11 Bn | 129.26 Bn | 2.84 Bn | 1.39 Bn |
| 2 | Regeneron Pharmaceuticals | 84.98 Bn | 76.99 Bn | 3.93 Bn | 1.53 Bn |
| 3 | Argenx Se | 64.52 Bn | 59.33 Bn | 1.37 Bn | 541.00 Mn |
| 4 | Moderna | 53.23 Bn | 48.09 Bn | 52.00 Mn | -767.00 Mn |
| 5 | BeOne Medicines | 41.23 Bn | 36.14 Bn | 1.53 Bn | 312.46 Mn |
| 6 | Alnylam Pharmaceuticals | 30.65 Bn | 27.34 Bn | 992.69 Mn | 177.81 Mn |
| 7 | Insmed | 27.15 Bn | 25.99 Bn | 358.27 Mn | -11.37 Mn |
| 8 | Royalty Pharma | 26.98 Bn | 26.14 Bn | - | 81.49 Mn |
| 9 | BioNTech SE | 26.78 Bn | 8.39 Bn | 668.28 Mn | -264.70 Mn |
| 10 | Spero Therapeutics | 70.14 Mn | 19.37 Mn | - | -9.55 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | -9.61 Mn |
| Mar 31, 2026 | -7.38 Mn |
| Dec 31, 2025 | 29.58 Mn |
| Sep 30, 2025 | -27.73 Mn |
| Jun 30, 2025 | -107.67 Mn |
| Mar 31, 2025 | -13.87 Mn |
| Dec 31, 2024 | -142.95 Mn |
| Sep 30, 2024 | -16.26 Mn |
| Jun 30, 2024 | -17.86 Mn |
| Mar 31, 2024 | -12.66 Mn |
| Dec 31, 2023 | -59.18 Mn |
| Sep 30, 2023 | -985,000.00 |
| Jun 30, 2023 | -11.91 Mn |
| Mar 31, 2023 | -13.27 Mn |
| Dec 31, 2022 | -92.37 Mn |
| Sep 30, 2022 | -11.84 Mn |
| Jun 30, 2022 | -26.07 Mn |
| Mar 31, 2022 | -34.09 Mn |
| Dec 31, 2021 | -129.95 Mn |
| Sep 30, 2021 | -55.73 Mn |