Spero Therapeutics (SPRO) EBT (2016 - 2026)
Spero Therapeutics (SPRO) reported EBT of -$7.2 million for Q1 2026, up 48.06% on a YoY basis from -$4.9 million in Q1 2025, and down 122.66% quarter-over-quarter from $31.8 million in Q4 2025.
Spero Therapeutics (SPRO) EBT (2016 - 2026) Analysis & Trends
Spero Therapeutics has reported EBT for 11 years, with the latest figure at -$7.2 million in Q1 2026.
- For the quarter ending Q1 2026, EBT rose 48.06% year-over-year to -$7.2 million; the trailing twelve-month figure through Mar 2026 stood at $15.5 million (up 121.07% YoY), and the FY2025 full-year result was $8.8 million, up 112.86% from the prior year.
- EBT for Q1 2026 stood at -$7.2 million, down from $31.8 million in the prior quarter.
- The five-year high for EBT was $55.5 million in Q4 2023, with the low at -$30.1 million in Q1 2022.
- Historically, EBT has averaged -$4.8 million across 5 years, with a median of -$11.9 million in 2023.
- Annual changes were most pronounced in 2024 — EBT sank 1669.41% — and 2025, when it soared 230.44%.
- Spero Therapeutics' EBT stood at $27.5 million in 2022, then soared by 101.91% to $55.5 million in 2023, then plunged by 143.9% to -$24.4 million in 2024, then soared by 230.44% to $31.8 million in 2025, then slumped by 122.66% to -$7.2 million in 2026.
- The last three EBT figures came in at -$7.2 million (Q1 2026), $31.8 million (Q4 2025), and -$7.4 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBT (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | -26.94 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -2.97 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 19.60 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.18 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -15.31 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | -1.50 Mn |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.25 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -56.48 Mn |
| 10 | Spero Therapeutics | 129.74 Mn | 73.61 Mn | - | -7.20 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -7.20 Mn |
| Dec 31, 2025 | 31.78 Mn |
| Sep 30, 2025 | -7.38 Mn |
| Jun 30, 2025 | -1.70 Mn |
| Mar 31, 2025 | -13.87 Mn |
| Dec 31, 2024 | -24.37 Mn |
| Sep 30, 2024 | -17.41 Mn |
| Jun 30, 2024 | -17.86 Mn |
| Mar 31, 2024 | -12.66 Mn |
| Dec 31, 2023 | 55.50 Mn |
| Sep 30, 2023 | -984,000.00 |
| Jun 30, 2023 | -11.91 Mn |
| Mar 31, 2023 | -13.26 Mn |
| Dec 31, 2022 | 27.49 Mn |
| Sep 30, 2022 | -11.47 Mn |
| Jun 30, 2022 | -25.97 Mn |
| Mar 31, 2022 | -30.14 Mn |
| Dec 31, 2021 | -27.43 Mn |
| Sep 30, 2021 | -22.43 Mn |
| Jun 30, 2021 | -18.46 Mn |