Spero Therapeutics SPRO
NASDAQ SPRO
$1.21 -0.02 (-1.63%)
At close: Aug 20, 2026 · 4:00 PM EDT

Spero Therapeutics (SPRO) EPS (Basic) (2016 - 2026)

Spero Therapeutics' (SPRO) quarterly EPS (Basic) came in at -$0.13 in Q1 2026, up 48.52% YoY from -$0.09 in Q1 2025, and down 124.63% on a QoQ basis from $0.52 in Q4 2025.

Spero Therapeutics (SPRO) EPS (Basic) (2016 - 2026) Analysis & Trends

Spero Therapeutics (SPRO) has 11 years of EPS (Basic) data on file, last reported at -$0.13 in Q1 2026.

  • Quarterly EPS (Basic) rose 48.52% year-over-year to -$0.13 in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$1.98 (up 42.55% YoY) and the FY2025 annual result came in at $0.09, up 102.61% from the prior year.
  • EPS (Basic) fell to -$0.13 in Q1 2026, from $0.52 in the prior quarter.
  • In the past five years, EPS (Basic) ranged from a high of $0.52 in Q4 2025 to a low of -$2.64 in Q4 2024.
  • A 5-year average of -$0.71 and a median of -$0.33 in 2022 frame the typical range for EPS (Basic).
  • The widest YoY moves for EPS (Basic): up 119.82% in 2025, down 480.46% in 2025.
  • Tracing SPRO's EPS (Basic) over 5 years: stood at -$2.46 in 2022, then soared by 54.01% to -$1.13 in 2023, then plunged by 133.59% to -$2.64 in 2024, then jumped by 119.82% to $0.52 in 2025, then plunged by 124.63% to -$0.13 in 2026.
  • The last three EPS (Basic) figures came in at -$0.13 (Q1 2026), $0.52 (Q4 2025), and -$0.49 (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EPS (Basic) (Qtr)
1 Vertex Pharmaceuticals 137.11 Bn 129.26 Bn 2.84 Bn 4.34
2 Regeneron Pharmaceuticals 84.98 Bn 76.99 Bn 3.93 Bn 12.62
3 Argenx Se 64.52 Bn 59.33 Bn 1.37 Bn 7.59
4 Moderna 53.23 Bn 48.09 Bn 52.00 Mn -1.96
5 BeOne Medicines 41.23 Bn 36.14 Bn 1.53 Bn 2.12
6 Alnylam Pharmaceuticals 30.65 Bn 27.34 Bn 992.69 Mn 1.23
7 Insmed 27.15 Bn 25.99 Bn 358.27 Mn -0.06
8 Royalty Pharma 26.98 Bn 26.14 Bn - 0.18
9 BioNTech SE 26.78 Bn 8.39 Bn 668.28 Mn -0.72
10 Spero Therapeutics 70.14 Mn 19.37 Mn - -0.16

Historic Data

Download Data
DateValue
Jun 30, 2026 -0.17
Mar 31, 2026 -0.13
Dec 31, 2025 0.52
Sep 30, 2025 -0.49
Jun 30, 2025 -1.92
Mar 31, 2025 -0.25
Dec 31, 2024 -2.64
Sep 30, 2024 -0.31
Jun 30, 2024 -0.33
Mar 31, 2024 -0.24
Dec 31, 2023 -1.13
Sep 30, 2023 -0.06
Jun 30, 2023 -0.23
Mar 31, 2023 -0.25
Dec 31, 2022 -2.46
Sep 30, 2022 -0.33
Jun 30, 2022 -0.79
Mar 31, 2022 -1.05
Dec 31, 2021 -4.21
Sep 30, 2021 -1.73